Anesthesiology and Intensive Care Unit


Introduction
Perioperative care for cancer patients with limited vital organ function is a major challenge for nesthesiologists as, in general, anesthesia and surgery may further deteriorate physiological functions. Perioperative impairment of vital organ function has traditionally been defined as surgical stress determined quantitatively by measuring the physiological parameters representing the corresponding organs. Recent evidence suggests that such a stress response to surgery involves not only vital organs but also the neuroendocrine- immune system and persists for several days after surgery. Thus, the aim of our anesthetic management is to protect patients from surgical stress by blocking the noxious influences of surgical trauma. This is achieved by regarding the anesthetic management as perioperative care.

Routine Activities 
As stated above, our colleagues (four staff anesthesiologists and one to two residents) are working as anesthetists and intensive care physicians.
In 2001, we performed 1972 anesthetic proce-dures. The annual number of patients admitted to the intensive care unit (ICU) amounted to 1127. Our concern in ICU management is not only postoperative cardiorespiratory care but also the critical care of patients who have developed organ failure after medical or surgical cancer treatment. The cumulative number of patients with organ failure treated in the ICU since the establishment of the National Cancer Center Hospital East is 265.
An outpatient clinic system was introduced in 1997 to improve preoperative evaluation of anesthetic risk in surgical patients and to participate in the management of intractable pain. In 2001, we performed analgesic nerve blocks in 4 cases. This system will further improve patient safety and the quality of pain control.
Daily activity starts with ICU rounds and pre-anesthesia case presentation. ICU rounds are also made every evening after the completion of elective surgical procedures. A journal club is held twice a week to maintain up-to-date knowledge of recent advances in anesthesia and critical care medicine.

New Developments
Ongoing clinical studies are as follows;
1) Establishment of perioperative management for abdominal surgery patients with severely limited pulmonary function.
2) Development of new intraoperative respiratory management for adequate ventilation and oxyge-nation.
3) Establishment of airway and respiratory manage-ment for patients with upper airway obstruction.
Future research activities will be directed toward the establishment of new methods of perioperative care in thefield of surgical oncology.

A. KOCHI

Number of Patients Managed Under General or Spinal/Epidural Anesthesia
Year
Total no.
Emergency cases
1995
1524
83 (5.4%)
1996
1584
62 (3.9%)
1997
1624
51 (3.1%)
1998
1642
45 (2.6%)
1999
1563
49 (3.1%)
2000
1742
62(3.6%)
2001
1972
68(3.4%)

Number of Patients Admitted to ICU
Year
No.of Cases
(Cases per month)
1995
671
(55.9)
1996
704
(58.7)
1997
755
(62.9)
1998
887
(73.9)
1999
959
(79.9)
2000
1027
(85.6)
2001
1127
(93.9)

Prognosis of Organ Failure Treated in ICU (1992.7. -2001.12)
Primary malignancy No. of pts Discharge* Death**
  Postoperative patients  
  Stomach
34
23
11
  Pancreas & biliary tract
36
9
27
  Colorectal
21
11
10
  Esophagus
15
9
6
  Head & neck
21
17
4
  Liver
11
5
6
  Panperitonitis
6
2
4
  Lung
13
4
9
  Others
7
3
4
Post-chemo-radiotherapy  
  Head & neck
16
4
12
  GI tract
20
6
14
  Lung
23
8
15
  Others
40
17
23
*Discharge is defined as discharge from the hospital. **Death includes patients who recovered from organ failure but subsequently died from the primary disease during hospitalization

Prognosis in Relation to the Number of Failed Organs
No. of failed organs
No. of pts
Discharge
Death
1
116
74
41
2
82
31
50
>3
67
10
57

Table of Contents