List of Papers Published in 2007

List of Researchers in 2007

  1. Breast Surgery
  2. Diagnostic Radiology
  3. Digestive Endoscopy & Gastrointestinal Oncology
  4. Head and Neck Surgery
  5. Hematology & Oncology
  6. Gastric, Hepatobiliary & Pancreatic Surgery
  7. Hepatobiliary & Pancreatic Oncology
  8. Colorectal (Pelvic) and Urological Surgery
  9. Plastic & Reconstructive Surgery
  10. Thoracic Oncology and Surgery
  11. Pathology Division
  12. Investigative Treatment Division
  13. Cancer Physiology Project
  14. Cancer Immunotherapy Project
  15. Functional Imaging division
  16. Psycho-Oncology Division
  17. Particle Therapy and Radiation Oncology Division

1. Breast Surgery

1. Imoto S, Wada N, Hasebe T, Ochiai A, Kitoh T. Serum c-erbB-2 protein is a useful marker for monitoring tumor recurrence of the breast. Int J Cancer 2007; 120: 357-361.

2. Wada N, Sakemura N, Imoto S, Hasebe T, Ochiai A, Moriyama N. Sentinel node biopsy in primary breast cancer: radioactive detection and metastatic disease. Eur J Surg Oncol 2007; 33:691-695.

2. Diagnostic Radiology

3. Sugiura S, Oda T, Aoyagi Y, Matsuo R, Enomoto T, Matsumoto K, Nakamura T, Satake M, Ochiai A, Ohkohchi N, Nakajima M. Microfabricated airflow nozzle for microencapsulation of living cells into 150 micrometer microcapsules. Biomed Microdevices 2007; 9: 91-99.

3. Digestive Endoscopy & Gastrointestinal Oncology

4. Horimatsu T, Fu KI, Sano Y, Yano T, Saito Y, Matsuda T, Fujimori T, Yoshida S. Acute appendicitis as a rare complication after endoscopic mucosal resection. Dig Dis Sci 2007; 52:1741-1744.

5. Katada C, Muto M, Momma K, Arima M, Tajiri H, Kanamaru C, Ooyanagi H, Endo H, Michida T, Hasuike N, Oda I, Fujii T, Saito D. Clinical outcome after endoscopic mucosal resection for esophageal squamous cell carcinoma invading the muscularis mucosae--a multicenter retrospective cohort study. Endoscopy 2007;39:779-783.

6. Fujishiro M, Takubo K, Sato Y, Kaise M, Niwa Y, Kato M, Muto M. Potential and present limitation of endocytoscopy in the diagnosis of esophageal squamous-cell carcinoma: a multicenter ex vivo pilot study. Gastrointest Endosc. 2007;66:551-555.

7. Muto M, Fujishiro M, Sato Y, Niwa Y, Kaise M, Kato M, Takubo K. Multicenter study design of the ex vivo evaluation of endoscopy in esophageal squamous cell carcinoma. Dig Endosc. 2007;19:S153-155.

8. Sano Y, Yoshida S. Optical Chromoeodoscopy using NBI during Screening Colonoscopy: Its usefulness and application. Review, NBI ATLAS. Comprehensive Atlas of High Resolution Endoscopy and Narrowband Imaging Edited by: Jonathan Cohen Blackwell. New York. 2007.

9. Sano Y, Fu KI, Ikematsu H. Review, Current Topics of Endoscopic diagnosis and Treatment for Colorectal Cancer in Japan. Acta Endoscopica 2007; 37:189-205.

10. Sano Y, Saitoh Y. Risk management of therapeutic colonoscopy (hot biopsy, polypectomy, endoscopic mucosal resection and endoscopic submucosal dissection). Digestive Endoscopy 2007;19(S1):S19-S25.

11. Fu KI, Kato S, Sano Y, Fujii T. Magnification with chromoendoscopy is the most reliable method to determine whether colorectal lesions are neoplastic or not. Endoscopy 2007;39:476.

12. Fu KI, Sano Y, Fujii T, Kaji Y, Fujimori T. Magnification or nonmagnification : that is a question. Am J Gastroenterol 2007; 102:1326.

13. Sano Y, Fu KI, Saito Y, Matsuda T, Uraoka T, Yoshino T, Yamaguchi Y, Fujita M, Hattori S, Ishikawa T, Saito D, Fujii T, Kaneko E, Yoshida S. Iatrogenic Perforation Associated with Therapeutic Colonoscopy: A Multicenter Study in Japan. J Gastroenterol Hepatol 2007;22:1409-1414.

14. Kobayashi N, Saito Y, Sano Y, Uragami N, Michita T, Nasu J, Matsuda T, Fu KI, Fujii T, Fujimori T, Ishikawa T, Saito D. Determining the treatment strategy for colorectal neoplastic lesions : endoscopic assessment or the non-lifting sign for diagnosing invasion depth? Endoscopy 2007;39:701-705.

15. Kaltenbach T, Sano Y, Friedland S, Soetikno R; American Gastroenterological Association. American Gastroenterological Association (AGA) Institute Technology Assessment on Image-Enhanced Endosccopy. Gastroenterology 2007;30:327-340.

16. Saito Y, Uraoka T, Matsuda T, Emura F, Ikehara H, Mashimo Y, Kikuchi T, Fu KI, Sano Y, Saito D. Endoscopic treatment of large superficial colorectal tumors: a case series of 200 endoscopic submucosal dissections (with video). Gastrointest Endosc 2007;66:966-973.

17. Kawaura K, Fujii S, Murata Y, Hasebe T, Ishii G, Itoh T, Sano Y, Saito N, Ochiai A. The lymphatic infiltration identified by D2-40 monoclonal antibody predicts lymph node metastasis in submucosal invasive colorectal cancer. Pathobiology 2007;74:328-335.

18. Kaneko K, Katagiri A, Konishi K, Kurahashi T, Ito H, Kumekawa Y, Yamamoto T, Muramoto T, Kubota Y, Nozawa H, Makino R, Kushima M, Imawari M. Study of p53 gene alteration as a biomarker to evaluate the malignant risk of Lugol-unstained lesion with non-dysplasia in the oesophagus. British Journal of Cancer 2007;96(3):492-498

19. Asakage T, Yokoyama A, Haneda T, Yamazaki M, Muto M, Yokoyama T, Kato H, Igaki H, Tsujinaka T, Kumagai Y, Yokoyama M, Omori T, Watanabe H. Genetic Polymorphisms of alcohol and aldehyde dehydrogenases, and drinking, smoking and diet in Japanese men with oral and pharyngeal squamous cell carcinoma. Carcinogenesis 2007;28:865-874.

20. Oyama Y, Isse T, Ogawa M, Muto M, Uchiyama I, Kawamoto T. Susceptibility to inhalation toxicity of acetaldehyde in Aldh2 knockout mice. Front Biosci 2007;12:1927-1934.

21. Boku N, Ohtsu A, Yoshida S, Shirao K, Shimada Y, Hyodo I, Saito H, Miyata Y. Significance of Biological Markers for Predicting Prognosis and Selecting Chemotherapy Regimens of Advanced Gastric Cancer Patients between Continuous Infusion of 5-FU and a Combination of 5-FU and Cisplatin. Jpn J Clin Oncol 2007; 37:275-281.

22. Fuse N, Doi T, Ohtsu A, Takeuchi S, Kojima T, Taku K, Tahara M, Muto M, Asaka M, Yoshida S. Feasibility of Oxaliplatin and Infusional Fluorouracil/Leucovorin (FOLFOX4) for Japanese Patients with Unresectable Metastatic Colorectal Cancer. Jpn J Clin Oncol 2007;37:434-439.

23. Boku N, Ohtsu A, Hyodo I, Shirao K, Miyata Y, Nakagawa K, Tamura T, Hatake K, Tanigawara Y. Phase II Study of Oxaliplatin in Japanese Patients with Metastatic Colorectal Cancer Refractory to Fluoropyrimidines. Jpn J Clin Oncol 2007;37:440-445.

24. Boku N, Ohtsu A, Nagashima F, Shirao K, Koizumi W. Relationship between Expression of Vascular Endothelial Growth Factor in Tumor Tissue from Gastric Cancers and Chemotherapy Effects: Comparison between S-1 alone and the Combination of S-1 plus CDDP. Jpn J Clin Oncol 2007;37:509-514.

25. Kawada K, Murakami K, Sato T, Kojima Y, Ebi H, Mukai H, Tahara M, Shimokata K, Minami H. Prospective Study of Positron Emission Tomography for Evaluation of the Activity of Lapatinib, a Dual Inhibitor of the ErbB1 and ErbB2 Tyrosine Kinases, in Patients with Advanced Tumors. Jpn J Clin Oncol 2007;37:44-48.

26. Hosokawa A, Sugiyama T, Ohtsu A, Doi T, Hattori S, Kojima T, Yano T, Minashi K, Muto M, Yoshida S. Long-term outcomes of patients with metastatic gastric cancer after initial S-1 monotherapy. J Gastroenterol 2007;42:533-538.

27. Maekawa K, Saeki M, Saito Y, Ozawa S, Kurose K, Kaniwa N, Kawamoto M, Kamatani N, Kato K, Hamaguchi T, Yamada Y, Shirao K, Shimada Y, Muto M, Doi T, Ohtsu A, Yoshida T, Matsumura Y, Saijo N, Sawada J. Genetic variations and haplotype structures of the DPYD gene encoding dihydropyrimidine dehydrogenase in Japanese and their ethnic differences. J Hum Genet 2007;52:804-819.

28. Kim SR, Sai K, Tanaka-Kagawa T, Jinno H, Ozawa S, Kaniwa N, Saito Y, Akasawa A, Matsumoto K, Saito H, Kamatani N, Shirao K, Yamamoto N, Yoshida T, Minami H, Ohtsu A, Saijo N, Sawada J. Haplotypes and a Novel Defective Allele of CES2 Found in a Japanese Population. Drug Metab Dispos 2007;35:1865-1872.

29. Minami H, Sai K, Saeki M, Saito Y, Ozawa S, Suzuki K, Kaniwa N, Sawada J, Hamaguchi T, Yamamoto N, Shirao K, Yamada Y, Ohmatsu H, Kubota K, Yoshida T, Ohtsu A, Saijo N. Irinotecan pharmacokinetics/pharmacodynamics and UGT1A genetic polymorphisms in Japanese: roles of UGT1A1*6 and *28. Pharmacogenet Genomics 2007;17:497-504.

30. Kim SR, Saito Y, Sai K, Kurose K, Maekawa K, Kaniwa N, Ozawa S, Kamatani N, Shirao K, Yamamoto N, Hamaguchi T, Kunitoh H, Ohe Y, Yamada Y, Tamura T, Yoshida T, Minami H, Ohtsu A, Saijo N, Sawada J. Genetic variations and frequencies of major haplotypes in SLCOB1B1 encoding the transporter OATP1B1 in Japanese subjects: SLCO1B1(*) 17 is more prevalent than (*) 15. Drug Metab Pharmacokinet 2007;22:456-461.

31. Ohtsu A. Diverse Eastern and Western approaches to the management of gastric cancer. Gastrointest Cancer Res 2007;1:S10-15.

32. Kawashima M, Hayashi R, Tahara M, Yamazaki M, Miyazaki M, Arahira S, Ogino T.  Accelerated Radiotherapy and Larynx Preservation in Favorable-risk Patients with T2 or Worse Hypopharyngeal Cancer. Jpn J Clin Oncol 2007;37:345-352.

33. Takeuchi S, Ohtsu A, Doi T, Kojima T, Minashi K, Mera K, Yano T, Tahara M, Muto M, Nihei K. A retrospective study of definitive chemoradiotherapy for elderly patients with esophageal cancer. Am J Clin Oncol 2007;30: 607-611.

34. Fujita H, Aikou T, Ohtsu A, et al: A new category for cancer in the esophagogastric junction based on lymph node compartments. Esophagus 2007;4:103-110.

4. Head and Neck Surgery

35. Shinozaki T, Hayashi R, Yamazaki M, Miyazaki M, Ugumori T, Sakuraba M, Ebihara S, Sarukawa S, Ichimura K. Palliative total pharyngo-laryngo-esophagectomy. Auris Nasus Larynx 2007; 34: 561-564.

36. Daiko H, Hayashi R, Saikawa M, Sakuraba M, Yamazaki M, Miyazaki M, Ugumori T, Asai M, Oyama W, Ebihara S. Surgical management of carcinoma of the cervical esophagus. J Surg Oncol 2007; 96:166-172.

5. Hematology & Oncology

37. Nakajima M, Komagata S, Fujiki Y, Kanada Y, Ebi H, Itoh K, Mukai H, Yokoi T, Minami H. Genetic polymorphisms of CYP2B6 affect the pharmacokinetics/pharmacodynamics of cyclophosphamide in Japanese cancer patients.Pharmacogenet and Genomics 2007;17:431-445.

38. Sugisaki K, Itoh K, Tamaru J. Acquired C1-esterase inhibitor deficiency and positive lupus anticoagulant accompanied by splenic marginal zone B-cell lymphoma. Clin Exp Rheumatol 2007; 25:627-629.

39. Mizuno T, Katsumata N, Mukai H, Shimizu C, Ando M, Watanabe T. The outpatient management of low-risk febrile patients with neutropenia: riskassessment over the telephone. Support Care Cancer 2007; 15: 287-291.

40. Mukohara T, Mukai H. Management of toxicity associated with chemotherapy for breast cancer. Nippon Rinsho 2007; 65 Suppl 6: 516-522.

41. Mukohara T and Janne PA. HER2 inhibition and clinical achievements. Targeted Therapies in Oncology: Clinical Achievements Taylor & Francis 2007; 45-54.

6. Gastric, Hepatobiliary & Pancreatic Surgery

42. Kobayashi A, Takahashi S, Ishii H, Konishi M, Nakagohri T, Gotohda N, Satake M, Furuse J, Kinoshita T. Factors predicting survival in advanced T-staged hepatocellular carcinoma patients treated with reduction hepatectomy followed by transcatheter arterial chemoembolization. Eur J Surg Oncol 2007; 33:1019-1024.

43. Konishi M, Kinoshita T, Nakagohri T, Takahashi S, Gotohda N, Ryu M. Pancreas-sparing duodenectomy for duodenal neoplasms including malignancies. Hepatogastroenterology 2007; 54:753-757.

44. Nakagohri T, Kinoshita T, Konishi M, Takahashi S, Tanizawa Y. Clinical results of extended lymphadenectomy and intraoperative radiotherapy for pancreatic adenocarcinoma. Hepatogastroenterology 2007; 54:564-569.

45. Nakagohri T, Kinoshita T, Konishi M, Takahashi S, Gotohda N. Surgical outcome of intraductal papillary mucinous neoplasms of the pancreas. Ann Surg Oncol 2007; 14:3174-80.

46. Takahashi S, Nagai K, Saito N, Konishi M, Nakagohri T, Gotohda N, Nishimura M, Yoshida J, Kinoshita T. Multiple resections for hepatic and pulmonary metastases of colorectal carcinoma.Jpn J Clin Oncol Informa 2007; 37:186-192.

47. Mitsunaga S, Hasebe T, Kinoshita T, Konishi K., Takahashi S, Gotohda N, Nakagohri T, Ochiai A. Detail histological analysis of nerve plexus invasion in invasive ductal carcinoma of the pancreas and its prognostic impact. Am J Surg Pathol2007; 31: 1636-1644.

48. Kajiwara M, Fujii S, Takahashi S, Konishi M, Nakagohri T, Gotohda N, Kinoshita T. Adenocarcinoma of the minor duodenal papilla with intraepithelial spread to the pancreatic duct. Virchows Arch 2007;451:1075-1781.

49. Kajiwara M, Gotohda N, Konishi M, Nakagohri T, Takahashi S, Kojima M, Hasebe T, Kinoshita T.Cystic endocrine tumor of the pancreas with an atypical multilocular appearance. J Hepatobiliary Pancreat Surg 2007; 14:586-589.

50. Tsujinaka T, Sasako M, Yamamoto S, Sano T, Kurokawa Y, Nashimoto A, Kurita A, Katai H, Shimizu T, Furukawa H, Inoue S, Hiratsuka M, Kinoshita T, Arai K, Yamamura Y. Influence of overweight on surgical complications for gastric cancer: Results from a randomized control trial comparing D2 and extended para-aortic D3 lymphadenectomy (JCOG9501). Ann Surg Oncol 2007; 14:355-361.

51. Nomura E, Sasako M, Yamamoto S, Sano T, Tsujinaka T, Kinoshita T, Furukawa H, Shimizu T, Hiratsuka M, Kobayashi O, Kurokawa Y, Tanigawa N. Risk factors for para-aortic lymph node metastasis of gastric cancer from a randomized controlled trial of JCOG9501. Jpn J Clin Oncol 2007;37: 429-433.

52. Sakuramoto S, Sasako M, Yamaguchi T, Kinoshita T, Fujii M, Nashimoto A, Furukawa H, Nakajima T, Ohashi Y, Imamura H, Higashino M, Yamamura Y, Kurita A, Arai K. Adjuvant chemotherapy for gastric cancer with s-1, an oral fluoropyrimidine. N Engl J Med 2007; 357: 1810-1820.

7. Hepatobiliary & Pancreatic Oncology

53. Ikeda M, Okusaka T, Ito Y, Ueno H, Morizane C, Furuse J, Ishii H, Kawashima M, Kagami Y, Ikeda H. A phase I trial of S-1 with concurrent radiotherapy for locally advanced pancreatic cancer.Br J Cancer 2007; 96:1650-1655.

54. Nakachi K, Furuse J, Ishii H, Suzuki E, Yoshino M. Prognostic factors in patients with gemcitabine-refractory pancreatic cancer. Jpn J Clin Oncol 2007; 37:114-120.

55. Furuse J, Ishii H, Kawashima M, Nagase M, Nakachi K, Ogino T, Yoshino M. A phase I study of hypofractionated radiotherapy followed by systemic chemotherapy with full-dose gemcitabine in patients with unresectable locally advanced pancreatic cancer. Hepatogastroenterology2007;54: 1575-1578.

56. Furuse J, Ishii H, Nakachi K, Suzuki E, Shimizu S, Yoshino M. Research advances in chemotherapy for pancreatic cancer in Japan. Res Adv in Gastroenterology 2007; 1:11-18.

57. Zytoon AA, Ishii H, Murakami K, El-Kholy MR, Furuse J, El-Dorry A, El-Malah A.Recurrence-free survival after radiofrequency ablation of hepatocellular carcinoma. A registry report of the impact of risk factors on outcome. Jpn J Clin Oncol 2007; 37: 658-672.

58. Yonemoto N, Furuse J, Okusaka T, Yamao K, Funakoshi A, Ohkawa S, Boku N, Tanaka K, Nagase M, Saisho H, Sato T. A multi-center retrospective analysis of survival benefits of chemotherapy for unresectable biliary tract cancer.Jpn J Clin Oncol 2007;37: 843-851.

8. Colorectal (Pelvic) and Urological Surgery

59. Saito N, Suzuki T, Sugito M, Ito M, Kobayashi A, Tanaka T, Kotaka M, Karaki H, Kobatake T, Tsunoda Y, Shiomi A, Yano M, Minagawa N, Nishizawa Y. Bladder-sparing extended resection of locally advanced rectal cancer involving the prostate and seminal vesicles. Surg Today 2007; 37: 845-852.

60. Kobayashi A, Sugito M, Ito M, Saito N. Predictors of successful salvage surgery for local pelvic recurrence of rectosigmoid colon and rectal cancers. Surg Today 2007; 37: 853-859.

61. Seike K, Koda K, Saito N, Oda K, Kosugi C, Shimizu K, Miyazaki M. Laser Doppler assessment of the influence of division at the root of the inferior mesenteric artery on anastomotic blood flow in rectosigmoid cancer surgery. Int J Colorectal Dis 2007;22: 689-697.

62. Fujita S, Saito N, Yamada T, Takii Y, Kondo K, Ohue M, Ikeda E, Moriya Y. Randomized, multicenter trial of antibiotic prophylaxis in elective colorectal surgery: single dose vs 3 doses of a second-generation cephalosporin without metronidazole and oral antibiotics. Arch Surg 2007; 142: 657-661.

9. Plastic & Reconstructive Surgery

63. Sarukawa S, Sakuraba M, Asano T, Yano T, Kimata Y, Hayashi R, Ebihara S. Immediate maxillary reconstruction after malignant tumor extirpation. Eur J Surg Oncol 2007; 33: 518-523.

10. Thoracic Oncology and Surgery

64. Niho S, Fujii H, Murakami K, Nagase S, Yoh K, Goto K, Ohmatsu H, Kubota K, Sekiguchi R, Nawano S, Saijo N, Nishiwaki Y. Detection of unsuspected distant metastases and/or regional nodes by FDG-PET in LD-SCLC scan in apparent limited-disease small-cell lung cancer. Lung Cancer 2007; 57:328-333.

65. Saijo T, Ishii G, Ochiai A, Hasebe T, Yoshida J, Nishimura M, Nagai K Evaluation of extratumoral lymphatic permeation in non-small cell lung cancer as a means of predicting outcome. Lung Cancer 2007; 55:61-66.

66. Nagai K, Sohara Y, Tsuchiya R, Goya T, Miyaoka E; Japan Lung Cancer Registration Committee. Prognosis of resected non-small cell lung cancer patients with intrapulmonary metastases. J Thorac Oncol 2007; 2:282-286.

67. Aokage K, Ishii G, Nagai K, Kawai O, Naito Y, Hasebe T, Nishimura M, Yoshida J, Ochiai A. Intrapulmonary metastasis in resected pathologic stage ⅢB non-small cell lung cancer: Possible contribution of aerogenous metastasis to the favorable outcome. J Thorac Cardiovasc Surg 2007; 134: 386-391.

68. Shiono S, Yoshida J, Nishimura M, Hagiwara M, Hishida T, Nitadori J, Nagai K. Risk factors of postoperative respiratory infections in lung cancer surgery. J Thorac Oncol 2007; 2: 34-38.

69. Nagai K, Yoshida J, Nishimura M. Postoperative mortality in lung cancer patients. Ann Thorac Cardiovasc Surg 2007; 13: 373-7.

70. Nishimura M, Daiko H, Yoshida J, Nagai K. Salvage esophagectomy following definitive Chemoradiotherapy. Gen Thorac Cardiovasc Surg 2007; 55: 461-465.

71. Aokage K, Yoshida J, Nishimura M, Nishiwaki Y, Nagai K. Annual abdominal ultrasonographic examination after curative NSCLC resection.Lung Cancer2007;57:334-338.

72. Ohe Y, Ohashi Y, Kubota K, Tamura T, Nakagawa K, Negoro S, Nishiwaki Y, Saijo N, Ariyoshi Y, Fukuoka M. Randomized phase III study of cisplatin plus irinotecan versus carboplatin plus paclitaxel, cisplatin plus gemcitabine, and cisplatin plus vinorelbine for advanced non-small-cell lung cancer: Four-Arm Cooperative Study in Japan. Ann Oncol 2007; 18: 317-23.

73. Yoh K, Kubota K, Kakinuma R, Ohmatsu H, Goto K, Niho S, Saijo N, Nishiwaki Y. Phase II trial of carboplatin and paclitaxel in non-small cell lung cancer patients previously treated with chemotherapy. Lung Cancer 2007; 58:73-79.

74. Yoh K, Niho S, Goto K, Ohmatsu H, Kubota K, Kakinuma R, Saijo N, Nishiwaki Y. Randomized trial of drip infusion versus bolus injection of vinorelbine for the control of local venous toxicity. Lung Cancer 2007; 55:337-341.

11. Pathology Division

75. Yonou H, Ochiai A, Ashimine S, Maeda H, Horiguchi Y, Yoshioka K, Ogawa Y, Hatano T, Tachibana M. The bisphosphonate YM529 inhibits osteoblastic bone tumor proliferation of prostate cancer.Prostate 2007;67: 999-1009.

76. Sano A, Sangai T, Maeda H, Nakamura M, Hasebe T, Ochiai A. Kallikrein 11 expressed in human breast cancer cell releases insulin-like growth factor through degradation of IGFBP-3. Int J Oncol 2007; 30: 1493-1498.

77. Miyamoto S, Nakamura M, Yano K, Ishii G, Hasebe T, Endoh Y, Sangai T, Maeda H, Shi-Chuang Z, Chiba T, Ochiai A. Matrix metalloproteinase-7 triggers the matricrine action of insulin-like growth factor-II via proteinase activity on insulin-like growth factor binding protein 2 in the extracellular matrix.Cancer Sci 2007;98:685-691.

78. Ito TK, Ishii G, Chiba H, Ochiai A. The VEGF angiogenic switch of fibroblasts is regulated by MMP-7 from cancer cells. Oncogene 2007;26: 7194-203.

79. Ishii G, Ito TK, Aoyagi K, Fujimoto H, Chiba H, Hasebe T, Fujii S, Nagai K, Sasaki H, Ochiai A. Presence of human circulating progenitor cells for cancer stromal fibroblasts in the blood of lung cancer patients.Stem Cells 2007; 25:1469-1477.

80. Yamauchi C, Hasebe T, Iwasaki M, Imoto S, Wada N, Fukuyama M, Ochiai A. Accurate assessment of lymph vessel tumor emboli in invasive ductal carcinoma of the breast according to tumor areas, and their prognostic significance. Hum Pathol 2007; 38: 247-259.

81. Ashida A, Boku N, Aoyagi K, Sato H, Tsubosa Y, Minashi K, Muto M, Ohtsu A, Ochiai A, Yoshida T, Yoshida S, Sasaki H. Expression profiling of esophageal squamous cell carcinoma patients treated with definitive chemoradiotherapy: Clinical implications. Int J Oncol 2006 28:1345-1352.

82. Naito Y, Ishii G, Kawai O, Hasebe T, Nishiwaki Y, Nagai K, Ochiai A. D2-40-positive solitary fibrous tumors of the pleura: Diagnostic pitfall of biopsy specimen. Pathol Int 2007; 59:618-621.

83. Kondo K, Takahashi Y, Hirose Y, Nagao T, Tsuyuguchi M, Hashimoto M, Ochiai A, Monden Y, Tangoku A. The reduced expression and aberrant methylation of p16(INK4a) in chromate workers with lung cancer. Lung Cancer 2006;53: 295-302.

84. Kon-No H, Ishii G, Nagai K, Yoshida J, Nishimura M, Nara M, Fujii T, Murata Y, Miyamoto H, Ochiai A. Carbonic anhydrase IX expression is associated with tumor progression and a poor prognosis of lung adenocarcinoma. Lung Cancer 2006 54:409-418.

85. Tsuruga M, Taki K, Ishii G, Sasaki Y, Furukawa C, Sugihara T, Nomura T, Ochiai A, Magae J. Amelioration of type II diabetes in db/db mice by continuous low-dose-rate gamma irradiation. Radiat Res 2007; 167:592-599.

12. Investigative Treatment Division

86. Matsumura Y. Preclinical and clinical studies of anticancer drug-incorporated polymeric micelles. J Drug Target 2007;15:507-517.

87. Hamaguchi T, Kato K, Yasui H, Morizane C, Ikeda M, Ueno H, Muro K, Yamada Y, Okusaka T, Shirao K, Shimada Y, Nakahama H, Matsumura Y. A phase I and pharmacokinetic study of NK105, a paclitaxel-incorporating micellar nanoparticle formulation. Br J Cancer 2007; 97:170-176.

88. Nakajima T, Yasunaga M, Kano Y, Koizumi F, Kato K, Hamaguchi T, Yamada Y, Shirao K, Shimada Y, Matsumura Y. Synergistic antitumor activity of the novel SN-38 incorporating polymeric micelles, NK012, combined with 5-fluorouracil in a mouse model of colorectal cancer, as compared with that of irinotecan plus 5-fluorouracil. Int J Cancer 2007; 9:2148-2153.

89. Onouchi S, Matsushita H, Nomura S, Minowa T, Matsumura Y. PCR-based assessment of the recovery rate of exfoliated colonocytes or cancer cells from fecal samples depends on the storage conditions after defecation. J Gastrointestin Liver Dis 2007; 16:369-372.

90. Yajima S, Ishii M, Matsushita H, Aoyagi K, Yoshimatsu K, Kaneko H, Yamamoto N, Teramoto T, Yoshida T, Matsumura Y, Sasaki H. Expression profiling of fecal colonocytes for RNA-based screening of colorectal cancer. Int J Oncol 2007; 31:1029-1037.

13. Cancer Physiology Project

91. Sato K, Tsuchihara K, Fujii S, Sugiyama M, Goya T, Atomi Y, Ueno T, Ochiai A, Esumi H. Autophagy is activated in colorectal cancer cells and contributes to the tolerance to nutrient deprivation. Cancer Res 2007;67: 9677-9684.

92. Win NN, Awale S, Esumi H, Tezuka Y, Kadota S. Bioactive secondary metabolites from Boesenbergia pandurata of Myanmar and their preferential cytotoxicity against human pancreatic cancer PANC-1 cell line in nutrient-deprived medium. J Nat Prod 2007;70:1582-1587.

93. Murakami YI, Yatabe Y, Sakaguchi T, Sasaki E, Yamashita Y, Morito N, Yoh K, Fujioka Y, Matsuno F, Hata H, Mitsuya H, Imagawa S, Suzuki A, Esumi H, Sakai M, Takahashi S, Mori N. c-Maf expression in angioimmunoblastic T-cell lymphoma. Am J Surg Pathol 2007;31: 1695-1702.

94. Minegishi Y, Tsukino H, Muto M, Goto K, Gemma A, Tsugane S, Kudoh S, Nishiwaki Y, Esumi H. Susceptibility to lung cancer and genetic polymorphisms in the alcohol metabolite-related enzymes alcohol dehydrogenase 3, aldehyde dehydrogenase 2, and cytochrome P450 2E1 in the Japanese population. Cancer 2007; 110: 353-362.

14. Cancer Immunotherapy Project

95. Yokomine K, Nakatsura T, Senju S, Nakagata N, Minohara M, Kira JI., Motomura Y, Kubo T, Sasaki Y, Nishimura Y. Regression of intestinal adenomas by vaccination with heat shock protein 105-pulsed bone marrow-derived dendritic cells in ApcMin/+ mice. Cancer Sci 2007;98: 1930-1935.

15. Functional Imaging division

96. Nasu K, Kuroki Y, Fujii H, Minami M. Hepatic pseudo-anisotropy: a specific artifact in hepatic diffusion-weighted images obtained with respiratory triggering. MAGMA 2007; 20: 205-211.

97. Tanaka E, Choi HS, Fujii H, Bawendi MG, Frangioni JV. Image-guided oncologic surgery using invisible light: completed pre-clinical development for sentinel lymph node mapping.Ann Surg Oncol 2006; 13:1671-1681.

98. Tanaka C, Fujii H, Ikeda T, Jinno H, Nakahara T, Suzuki T, Kitagawa Y, Kitajima M, Ando Y, Kubo A. Stereoscopic scintigraphic imaging of breast cancer sentinel lymph nodes. Breast Cancer 2007; 14:92-99.

99. Fujii H, Yamagishi H, Ando Y, Tsukamoto N, Kawaguchi O, Kasamatsu T, Kurosaki K, Osada M, Kaneko H, Kubo A. Structuring of free-text diagnostic report. Stud Health Technol Inform 2007; 129: 669-673.

16. Psycho-Oncology Division

100. Akechi T, Taniguchi K, Suzuki S, Okamura M, Minami H, Okuyama T, Furukawa TA, Uchitomi Y. Multifaceted psychosocial intervention program for breast cancer patients after first recurrence: feasibility study. Psychooncology 2007; 16: 517-524.

101. Shimizu K, Akechi T, Shimamoto M, Okamura M, Nakano T, Murakami T, Ito T, Oba A, Fujimori M, Akizuki N, Inagaki M, Uchitomi Y. Can psychiatric intervention improve major depression in very near end-of-life cancer patients? Palliat Support Care 2007;5:3-9.

102. Inagaki M, Yoshikawa E, Kobayakawa M, Matsuoka Y, Sugawara Y, Nakano T, Akizuki N, Fujimori M, Akechi T, Kinoshita T, Furuse J, Murakami K, Uchitomi Y. Regional cerebral glucose metabolism in patients with secondary depressive episodes after fatal pancreatic cancer diagnosis. J Affect Disord 2007;99: 231-236.

103. Fujimori M, Akechi T, Morita T, Inagaki M, Akizuki N, Sakano Y, Uchitomi Y . Preferences of cancer patients regarding the disclosure of bad news. Psychooncology 2007; 16:573-581.

104. Fujimori M, Parker PA, Akechi T, Sakano Y, Baile WF, Uchitomi Y. Japanese cancer patients' communication style preferences when receiving bad news. Psychooncology 2007; 16: 617-625.

105. Miyashita M, Sanjo M, Morita T, Hirai K, Kizawa Y, Shima Y, Shimoyama N, Tsuneto S, Hiraga K, Sato K, Uchitomi Y. Barriers to providing palliative care and priorities for future actions to advance palliative care in Japan: a nationwide expert opinion survey. J Palliat Med 2007;10:390-399.

106. Morita T, Bito S, Koyama H, Uchitomi Y, Adachi I. Development of a national clinical guideline for artificial hydration therapy for terminally ill patients with cancer.J Palliat Med 2007; 10:770-780.

107. Miyashita M, Sanjo M, Morita T, Hirai K, Uchitomi Y. Good death in cancer care: a nationwide quantitative study.Ann Oncol 2007; 18:1090-1097.

108. Asai M, Morita T, Akechi T, Sugawara Y, Fujimori M, Akizuki N, Nakano T, Uchitomi Y. Burnout and psychiatric morbidity among physicians engaged in end-of-life care for cancer patients: a cross-sectional nationwide survey in Japan. Psychooncology 2007;16: 421-428.

109. Nagamine M, Matsuoka Y, Mori E, Fujimori M, Imoto S, Kim Y, Uchitomi Y. Relationship between heart rate and emotional memory in subjects with a past history of post-traumatic stress disorder.Psychiatry Clin Neurosci 2007;61:441-443.

110. Tsuchiya M, Iwasaki M, Otani T, Nitadori J, Goto K, Nishiwaki Y, Uchitomi Y, Tsugane S. Breast Cancer in First-degree Relatives and Risk of Lung Cancer: Assessment of the Existence of Gene Sex Interactions. Jpn J Clin Oncol 2007; 37:419-423.

111. Morita T, Murata H, Hirai K, Tamura K, Kataoka J, Ohnishi H, Akizuki N, Kurihara Y, Akechi T, Uchitomi Y; on Behalf of the Japanese Spiritual Care Task Force. Meaninglessness in terminally ill cancer patients: a validation study and nurse education intervention trial.J Pain Symptom Manage 2007;34: 160-170.

112. Matsuoka Y, Nagamine M, Mori E, Imoto S, Kim Y, Uchitomi Y. Left hippocampal volume inversely correlates with enhanced emotional memory in healthy middle-aged women.J Neuropsychiatry Clin Neurosci2007;19:335-338.

113. Nagamine M, Matsuoka Y, Mori E, Fujimori M, Imoto S, Kim Y, Uchitomi Y. Different emotional memory consolidation in cancer survivors with and those without a history of intrusive recollection. J Trauma Stress 2007;20: 727-736.

114. Sanjo M, Miyashita M, Morita T, Hirai K, Kawa M, Akechi T, Uchitomi Y. Preferences regarding end-of-life cancer care and associations with good-death concepts: a population-based survey in Japan.Ann Oncol 2007;18:1539-1547.

115. Akechi T, Okuyama T, Akizuki N, Shimizu K, Inagaki M, Fujimori M, Shima Y, Furukawa TA, Uchitomi Y. Associated and predictive factors of sleep disturbance in advanced cancer patients. Psychooncology 2007; 16:888-894.

116. Hakamata Y, Matsuoka Y, Inagaki M, Nagamine M, Hara E, Imoto S, Murakami K, Kim Y, Uchitomi Y Structure of orbitofrontal cortex and its longitudinal course in cancer-related post-traumatic stress disorder. Neurosci Res 2007; 59:383-389.

117. Morita T, Akechi T, Ikenaga M, Inoue S, Kohara H, Matsubara T, Matsuo N, Namba M, Shinjo T, Tani K, Uchitomi Y Terminal delirium: recommendations from bereaved families' experiences. J Pain Symptom Manage 2007; 34: 579-589.

118. Shimizu K, Kinoshita H, Akechi T, Uchitomi Y, Andoh M. First panic attack episodes in head and neck cancer patients who have undergone radical neck surgery. J Pain Symptom Manage 2007;34: 575-578.

119. Inagaki M, Yoshikawa E, Matsuoka Y, Sugawara Y, Nakano T, Akechi T, Wada N, Imoto S, Murakami K, Uchitomi Y. Smaller regional volumes of brain gray and white matter demonstrated in breast cancer survivors exposed to adjuvant chemotherapy. Cancer 2007; 109:146-156.

120. Inagaki M, Uchitomi Y, Imoto S. Author reply. Cancer 2007; 110:225.

17. Particle Therapy and Radiation Oncology Division

121. Zenda S, Onozawa Y, Boku N, Iida Y, Ebihara M, Onitsuka T. Single-agent Docetaxel in Patients with Platinum-refractory Metastatic or Recurrent Squamous Cell Carcinoma of the Head and Neck (SCCHN). Jpn J Clin Oncol 2007; 37:477-481.

122. Zenda S, Onozawa Y, Tahara M, Kawashima M, Shikama N, Sasaki S. Feasibility study of single agent cisplatin and concurrent radiotherapy in Japanese patients with squamous cell carcinoma of the head and neck: Preliminary results. Jpn J Clin Oncol 2007; 37:725-729.

123. Kawashima M, Hayashi R, Tahara M, Yamazaki M, Miyazaki M, Arahira S, Ogino T. Accelerated Radiotherapy and Larynx Preservation in Favorable-risk Patients with T2 or Worse Hypopharyngeal Cancer. Jpn J Clin Oncol 2007; 37: 345-352.

124. Isobe K, Kagami Y, Higuchi K, Kodaira T, Hasegawa M, Shikama N, Nakazawa M, Fukuda I, Nihei K, Ito K, Teshima T, Oguchi M. Initial experience with the quality assurance program of radiation therapy on behalf of Japan Radiation Oncology Group (JAROG) Jpn J Clin Oncol 2007; 37:135-139.

125. Matsuo Y, Takayama K, Nagata Y, Kunieda E, Tateoka K, Ishizuka N, Mizowaki T, Norihisa Y, Sakamoto M, Narita Y, Ishikura S, Hiraoka M. Interinstitutional variations in planning for stereotactic body radiation therapy for lung cancer. Int J Radiat Oncol Biol Phys 2007; 68:416-425.

126. Nishimura H, Ogino T, Kawashima M, Nihei K, Arahira S, Onozawa M, Katsuta S, Nishio T. Proton-beam therapy for olfactory neuroblastoma. Int J Radiat Oncol Biol Phys 2007; 68: 758-762.

127. Nishio T, Inaniwa T, Inoue K, Miyatake A, Nakagawa K, Yoda K, Ogino T. Experimental verification of the utility of positron emitter nuclei generated by photonuclear reactions for X-ray beam monitoring in a phantom. Radiat Med 2007; 25:516-522.


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