List of Papers Published in 2008

List of Researchers in 2008

  1. Breast Surgery
  2. Diagnostic Radiology
  3. Endoscopy & Gastrointestinal Oncology
  4. Hematology & Oncology
  5. Gastric, Hepatobiliary & Pancreatic Surgery
  6. Hepatobiliary & Pancreatic Oncology
  7. Colorectal (Pelvic) & Urological Surgery
  8. Plastic & Reconstructive Surgery
  9. Thoracic Oncology
  10. Thoracic Surgery
  11. Pathology Division
  12. Investigative Treatment Division
  13. Cancer Physiology Project
  14. Cancer Immunotherapy Project
  15. Functional Imaging Division
  16. Psycho-Oncology Division
  17. Particle Therapy and Radiation Oncology Division

1. Breast Surgery

1Wada N, Imoto S. Clinical evidence of breast cancer micrometastasis in the era of sentinel node biopsy. Int J Clin Oncol. 2008;13:24-32.

2Tanaka K, Imoto S, Wada N, Sakemura N, Hasebe K. Invasive apocrine carcinoma of the breast: clinicopathologic features of 57 patients.Breast J. 2008;14:164-8.

3Hasebe T, Imoto S, Yokose T, Ishii G, Iwasaki M, Wada N.Histopathologic factors significantly associated with initial organ-specific metastasis by invasive ductal carcinoma of the breast: a prospective study. Hum Pathol. 2008;39:681-93.

2. Diagnostic Radiology

4 Satake M, Uchida H, Arai Y, Anai H, Sakaguchi H, Nagata T, Yamane T, Kichikawa K, Osaki Y, Okazaki M, Higashihara H, Nakamura H, Osuga K, Nakao N, Hirota S. Transcatheter arterial chemoembolization (TACE) with lipiodol to treat hepatocellular carcinoma: survey results from the TACE study group of Japan.Cardiovasc Intervent Radiol.2008;31(4):756-61.

5Morimoto K, Sakaguchi H, Tanaka T, Yamamoto K, Anai H, Hayashi T, Satake M, Kichikawa K.Transarterial chemoembolization using cisplatin powder in a rabbit model of liver cancer.Cardiovasc Intervent Radiol.2008;31(5):981-5.

6Sugiura S, Oda T, Aoyagi Y, Satake M, Ohkohchi N, Nakajima M.Tubular gel fabrication and cell encapsulation in laminar flow stream formed by microfabricated nozzle array. Lab Chip. 2008;8(8):1255-7.

7Kobayashi T, Hayashi T, Funabasama S, Tsukagoshi S, Minami M, Moriyama N. Three-dimensional perfusion imaging of hepatocellular carcinoma using 256-slice multidetector-row computed tomography.Radiat Med. 2008;26(9):557-61.

3. Endoscopy & Gastrointestinal Oncology

8Ohtsu A. Chemotherapy for metastatic gastric cancer: past present and future. J Gastroenterol 2008;43:256-64.

9Katagiri A, Fu K-I, Sano Y, Ikematsu H, Horimatsu T, Kaneko K, Muto M, Yoshida S. Narrow band imaging with magnifying colonoscopy as diagnostic tool for predicting histology of early colorectal neoplasia.Aliment Pharmacol Ther. 2008;27:1269−74.

10Emura F, Saito Y, Ikematsu H. Narrow-band imaging optical chromocolonoscopy: advantages and limitations. World J Gastroenterol.2008;14(31):4867-72.

11Matsuda T, Fujii T, Saito Y, Nakajima T, Uraoka T, Kobayashi N, Ikehara H, Ikematsu H, Fu KI, Emura F, Ono A, Sano Y, Shimoda T, Fujimori T.Efficacy of the invasive/non-invasive pattern by magnifying chromoendoscopy to estimate the depth of invasion of early colorectal neoplasms. Am J Gastroenterol.2008;103(11):2700-6.

12Yamamoto H, Yahagi N, Oyama T, Gotoda T, Doi T, Hirasaki S, Shimoda T, Sugano K, Tajiri H, Takekoshi T, Saito D.Usefulness and safety of 0.004 sodium hyaluronate solution as a submucosal fluid cushion in endoscopic resection for gastric neoplasms: a prospective multicenter trial.Gastrointest Endosc.2008;67:830-9.

13Yano T, Muto M, Hattori S, Minashi K, Onozawa M, Nihei K, Ishikura S, Ohtsu A, Yoshida S. Long-term results of salvage endoscopic mucosal resection in patients with local failure after definitive chemoradiotherapy for esophageal squamous cell carcinoma. Endoscopy.2008;40(9):717-21.

14Yamada Y, Tahara M, Miya T, Satoh T, Shirao K, Shimada Y, Ohtsu A, Sasaki Y, Tanigawara Y.Phase I/II study of oxaliplatin with oral S-1 as first-line therapy for patients with metastatic colorectal cancer.Br J Cancer. 2008;98:1034-8.

15Minami H, Kawada K, Ebi H, Kitagawa K, Kim YI, Araki K, Mukai H, Tahara M, Nakajima H, Nakajima K. Phase I and pharmacokinetic study of sorafenib, an oral multikinase inhibitor, in Japanese patients with advanced refractory solid tumors. Cancer Sci. 2008;99:1492-8.

16Tahara M, Shirao K, Boku N, Yamaguchi K, Komatsu Y, Inaba Y, Arai T, Mizunuma N, Satoh T, Takiuchi H, Nishina T, Sakata Y.Multicenter Phase II Study of Cetuximab Plus Irinotecan in Metastatic Colorectal Carcinoma Refractory to Irinotecan, Oxaliplatin and Fluoropyrimidines. Jpn J Clin Oncol.2008;38(11):762-9.

17Nishida T, Shirao K, Sawaki A, Koseki M, Okamura T, Ohtsu A, Sugiyama T, Miyakawa K, Hirota S.Efficacy and safety profile of imatinib mesylate (ST1571) in Japanese patients with advanced gastrointestinal stromal tumors: a phase II study (STI571B1202).Int J Clin Oncol. 2008;13(3):244-51.

18Hamaguchi T, Shirao K, Yamamichi N, Hyodo I, Koizumi W, Seki S, Imamura T, Honma H, Ohtsu A, Boku N, Mukai T, Yamamoto S, Fukuda H, Yoshida S; Gastrointestinal Oncology Study Group of Japan Clinical Oncology Group.A phase II study of sequential methotrexate and 5-fluorouracil chemotherapy in previously treated gastric cancer: a report from the Gastrointestinal Oncology Group of the Japan Clinical Oncology Group, JCOG 9207 trial.Jpn J Clin Oncol.2008;38(6):432-7.

19Shima Y, Ohtsu A, Shirao K, Sasaki Y.Clinical efficacy and safety of octreotide (SMS201-995) in terminally ill Japanese cancer patients with malignant bowel obstruction. Jpn J Clin Oncol.2008;38(5):354-9.

20Kiyota N, Tahara M, Fujii S, Kawashima M. Nonplatinum-based Chemotherapy With Irinotecan Plus Docetaxel for Advanced or Metastatic Olfactory Neuroblastoma. Cancer. 2008;112:885-91.

21Yamazaki K, Hironaka S, Boku N, Yasui H, Fukutomi A, Yoshino T, Onozawa Y, Hasuike N, Inui T, Yamaguchi Y, Ono H.A retrospective study of second-line chemotherapy for unresectable or recurrent squamous cell carcinoma of the esophagus refractory to chemotherapy with 5-fluorouracil plus platinum. Int J Clin Oncol 2008;13:150−155.

22Zenda S, Hironaka S, Boku N, Yamazaki K, Yasui H, Fukutomi A, Yoshino T, Onozawa Y, Nishimura T.Impact of hemoglobin level on survival in definitive chemoradiotherapy for T4/M1 lymph node esophageal cancer. Dis Esophagus. 2008;21:195−200.

23Kogo M, Suzuki A, Kaneko K, Yoneyama K, Imawari M, Kiuchi Y.Scoring system for predicting response to chemoradiotherapy, including 5-Fluorouracil and platinum, for patients with esophageal cancer. Dig Dis Sci. 2008;53(9):2415-21.

24Taira K, Boku N, Fukutomi A, Onozawa Y, Hironaka S, Yoshino T, Yasui H, Yamazaki K, Taku K, Hashimoto T, Nishimura T.Results of a retrospective analysis of gemcitabine as a second-line treatment after chemoradiotherapy and maintenance chemotherapy using 5-fluorouracil in patients with locally advanced pancreatic cancer. J Gastroenterol. 2008;43(11):875-80.

25Fuse N, Doi T, Ohtsu A, Yano T, Minashi K, Tahara M, Muto M, Asaka M, Yoshida S. Safety of irinotecan and infusional fluorouracil/leucovorin (FOLFIRI) in Japan: a retrospective review of 48 patients with metastatic colorectal cancer.Int J Clin Oncol. 2008;13:144-9.

26Machida N, Yoshino T, Boku N, Hironaka S, Onozawa Y, Fukutomi A, Yamazaki K, Yasui H, Taku K, Asaka M.Impact of baseline sum of longest diameter in target lesions by RECIST on survival of patients with metastatic colorectal cancer. Jpn J Clin Oncol. 2008;38(10):689-94.

4. Hematology & Oncology

27Ogawa Y, Tobinai K, Ogura M, Ando K, Tsuchiya T, Kobayashi Y, Watanabe T, Maruyama D, Morishima Y, Kagami Y, Taji H, Minami H, Itoh K, Nakata M, Hotta T. Phase I and II pharmacokinetic and pharmacodynamic study of the proteasome inhibitor bortezomib in Japanese patients with relapsed or refractory multiple myeloma. Cancer Sci. 2008;99:140-4.

28Sai K, Saito Y, Itoda M, Fukushima-Uesaka H, Nishimaki-Mogami T, Ozawa S, Maekawa K, Kurose K, Kaniwa N, Kawamoto M, Kamatani N, Shirao K, Hamaguchi T, Yamamoto N, Kunitoh H, Ohe Y, Yamada Y, Tamura T, Yoshida T, Minami H, Matsumura Y, Ohtsu A, Saijo N, SGenetic variations and haplotypes of ABCC2 encoding MRP2 in a Japanese population.Drug Metab Pharmacokinet. 2008; 23(2):139-47.

29Yakushiji S, Tateishi U, Nagai S, Matsuno Y, Nakagawa K, Asamura H, Kusumoto M.Computed tomographic findings and prognosis in thymic epithelial tumor patients.J Comput Assist Tomogr.2008;32(5):799-805.

5. Gastric, Hepatobiliary & Pancreatic Surgery

30Sasako M, Sano T, Yamamoto S, Kurokawa Y, Nashimoto A, Kurita A, Hiratsuka M, Tsujinaka T, Kinoshita T, Arai K, Yamamura Y, Okajima K; Japan Clinical Oncology Group.D2 lymphadenectomy alone or with para-aortic nodal dissection for gastric cancer.Engl J Med. 2008;359(5):453-62.

31Nakagohri T, Yoneyama Y, Kinoshita T, Konishi M, Inoue K, Takahashi S. Prognostic significance of peritoneal washing cytology in patients with potentially resectable gastric cancer. Hepatogastroenterology. 2008;55(86-87):1913-5.

32Nobuoka D, Gotohda N, Konishi M, Nakagohri T, Takahashi S, Kinoshita T. Prevention of postoperative pancreatic fistula after total gastrectomy. World J Surg. 2008;32(10):2261-6.

33Nakagohri T, Kinoshita T, Konishi M, Takahashi S, Gotohda N.Surgical outcome and prognostic factors in intrahepatic cholangiocarcinoma.World J Surg. 2008;32(12):2675-80.

34Maeda A, Boku N, Fukutomi A, Kondo S, Kinoshita T, Nagino M, Uesaka K. Randomized phase III trial of adjuvant chemotherapy with gemcitabine versus S-1 in patients with resected pancreatic cancer: Japan Adjuvant Study Group of Pancreatic Cancer (JASPAC-01).Jpn J Clin Oncol.2008;38(3):227-9.

35Kajiwara M, Gotohda N, Konishi M, Nakagohri T, Takahashi S, Kojima M, Kinoshita T. Incidence of the focal type of autoimmune pancreatitis in chronic pancreatitis suspected to be pancreatic carcinoma: Experience of a single tertiary cancer center.Scand J Gastroenterol.2008;43(1):110-6.

36Kajiwara M, Kojima M, Konishi M, Nakagohri T, Takahashi S, Gotohda N, Hasebe T, Ochiai A, Kinoshita T.Autoimmune pancreatitis with multifocal lesions. J Hepatobiliary Pancreat Surg. 2008;15(4):449-52.

37Nakagohri T, Kinoshita T, Konishi M, Takahashi S, Gotohda N.Surgical outcome of solid pseudopapillary tumor of the pancreas. J Hepatobiliary Pancreat Surg.2008;15(3):318-21.

38Kato Y, Nakagouri T, Konishi M, Takahashi S, Gotoda N, Hasebe T, Kinosita T. Intraductal oncocytic papillary neoplasm of the pancreas with strong accumulation on FDG-PET. Hepatogastroenterology. 2008;55(84):900-2.

39Mitsunaga S, Kinoshita T, Hasebe T, Nakagohri T, Konishi M, Takahashi S, Gotohda N, Ochiai A. Low serum level of cholinesterase at recurrence of pancreatic cancer is a poor prognostic factor and relates to systemic disorder and nerve plexus invasion.Pancreas.2008;36(3):241-8.

40Hasebe T, Konishi M, Iwasaki M, Nakagohri T, Takahashi S, Gotohda N, Kinoshita T, Ochiai A. Primary tumor/vessel tumor/nodal tumor classification of extrahepatic bile duct carcinoma.Hum Pathol.2008;39(1):37-48.

41Gotohda N, Iwagaki H, Ozaki M, Kinoshita T, Konishi M, Nakagohri T, Takahashi S, Saito S, Yagi T, Tanaka N.Deficient response of IL-6 impaired liver regeneration after hepatectomy in patients with viral hepatitis. Hepatogastroenterology. 2008;55(85):1439-44.

42Gotohda N, Iwagaki H, Ozaki M, Kinoshita T, Konishi M, Nakagohri T, Takahashi S, Saito S, Yagi T, Tanaka N.Significant correlation between surgical stress of hepatectomy and changes in the serum levels of HGF, IL-6 and soluble Fas in patients with viral hepatitis. Hepatogastroenterology. 2008;55(85):1400-3.

6. Hepatobiliary & Pancreatic Oncology

43Furuse J, Ishii H, Nakachi K, Suzuki E, Shimizu S, Nakajima K. Phase I study of sorafenib in Japanese patients with hepatocellular carcinoma.Cancer Sci. 2008;99:159-65.

44Furuse J, Okusaka T, Boku N, Ohkawa S, Sawaki A, Masumoto T, Funakoshi A. S-1 monotherapy as first-line treatment in patients with advanced biliary tract cancer: a multicenter phase II study.Cancer Chemother Pharmacol.2008;62:849-55.

45Thomas MB, O'Beirne JP, Furuse J, Chan AT, Abou-Alfa G, Johnson P. Systemic therapy for hepatocellular carcinoma: cytotoxic chemotherapy, targeted therapy and immunotherapy. Ann Surg Oncol.2008;15:1008-14.

46Furuse J, Takada T, Miyazaki M, Miyakawa S, Tsukada K, Nagino M, Kondo S, Saito H, Tsuyuguchi T, Hirata K, Kimura F, Yoshitomi H, Nozawa S, Yoshida M, Wada K, Amano H, Miura F; Japanese Association of Biliary Surgery; Japanese Society of Hepato-Biliary-PaGuidelines for chemotherapy of biliary tract and ampullary carcinomas.J Hepatobiliary Pancreat Surg.2008;15:55-62.

47Okusaka T, Ito Y, Furuse J, Yamada S, Ishii H, Shibuya K, Ioka T, Shinchi H. Current status of chemoradiotherapy for locally advanced pancreatic cancer in Japan. Int J Clin Oncol.2008;13:127-31.

48Matsubara J, Okusaka T, Morizane C, Ikeda M, Ueno H. Ultrasound-guided percutaneous pancreatic tumor biopsy in pancreatic cancer: a comparison with metastatic liver tumor biopsy, including sensitivity, specificity, and complications. J Gastroenterol.2008;43:225-32.

49Tsuyuguchi T, Takada T, Miyazaki M, Miyakawa S, Tsukada K, Nagino M, Kondo S, Furuse J, Saito H, Suyama M, Kimura F, Yoshitomi H, Nozawa S, Yoshida M, Wada K, Amano H, Miura F; Japanese Association of Biliary Surgery; Japanese Society of Hepato-Biliary-Pa Stenting and interventional radiology for obstructive jaundice in patients with unresectable biliary tract carcinomas.J Hepatobiliary Pancreat Surg. 2008;15:69-73.

50Saito H, Takada T, Miyazaki M, Miyakawa S, Tsukada K, Nagino M, Kondo S, Furuse J, Tsuyuguchi T, Kimura F, Yoshitomi H, Nozawa S, Yoshida M, Wada K, Amano H, Miura F; Japanese Association of Biliary Surgery; Japanese Society of Hepato-Biliary-Pancreatic SRadiation therapy and photodynamic therapy for biliary tract and ampullary carcinomas. J Hepatobiliary Pancreat Surg. 2008;15::63-8.

51Kondo S, Takada T, Miyazaki M, Miyakawa S, Tsukada K, Nagino M, Furuse J, Saito H, Tsuyuguchi T, Yamamoto M, Kayahara M, Kimura F, Yoshitomi H, Nozawa S, Yoshida M, Wada K, Hirano S, Amano H, Miura F; Japanese Association of Biliary Surgery; Japanese SociGuidelines for the management of biliary tract and ampullary carcinomas: surgical treatment.J Hepatobiliary Pancreat Surg.2008;15:41-54.

52Tsukada K, Takada T, Miyazaki M, Miyakawa S, Nagino M, Kondo S, Furuse J, Saito H, Tsuyuguchi T, Kimura F, Yoshitomi H, Nozawa S, Yoshida M, Wada K, Amano H, Miura F; Japanese Association of Biliary Surgery; Japanese Society of Hepato-Biliary-Pancreatic Surgery; Japan Society of Clinical Oncology. Diagnosis of biliary tract and ampullary carcinomas. J Hepatobiliary Pancreat Surg. 2008;15:31-40.

53Nagino M, Takada T, Miyazaki M, Miyakawa S, Tsukada K, Kondo S, Furuse J, Saito H, Tsuyuguchi T, Yoshikawa T, Ohta T, Kimura F, Ohta T, Yoshitomi H, Nozawa S, Yoshida M, Wada K, Amano H, Miura F; Japanese Association of Biliary Surgery; Japanese Society of Hepato-Biliary-Pancreatic Surgery; Japan Society of Clinical Oncology. Preoperative biliary drainage for biliary tract and ampullary carcinomas. J Hepatobiliary Pancreat Surg.2008;15:25-30.

54Miyazaki M, Takada T, Miyakawa S, Tsukada K, Nagino M, Kondo S, Furuse J, Saito H, Tsuyuguchi T, Chijiiwa K, Kimura F, Yoshitomi H, Nozawa S, Yoshida M, Wada K, Amano H, Miura F; Japanese Association of Biliary Surgery; Japanese Society of Hepato-PancreatRisk factors for biliary tract and ampullary carcinomas and prophylactic surgery for these factors. J Hepatobiliary Pancreat Surg. 2008;15:15-24.

55Miyakawa S, Ishihara S, Takada T, Miyazaki M, Tsukada K, Nagino M, Kondo S, Furuse J, Saito H, Tsuyuguchi T, Kimura F, Yoshitomi H, Nozawa S, Yoshida M, Wada K, Amano H, Miura F; Japanese Association of Biliary Surgery; Japanese Society of Hepato-Biliary-Flowcharts for the management of biliary tract and ampullary carcinomas.J Hepatobiliary Pancreat Surg.2008;15:7-14.

56Takada T, Miyazaki M, Miyakawa S, Tsukada K, Nagino M, Kondo S, Furuse J, Saito H, Tsuyuguchi T, Kimura F, Yoshitomi H, Nozawa S, Yoshida M, Wada K, Amano H, Miura F; Japanese Association of Billiary Surgery; Japanese Society of Hepato-Biliary-Pancreatic Surgery; Japan Society of Clinical Oncology. Purpose, use, and preparation of clinical practice guidelines for the management of biliary tract and ampullary carcinomas.J Hepatobiliary Pancreat Surg.2008;15:2-6.

57Ohnami S, Sato Y, Yoshimura K, Ohnami S, Sakamoto H, Aoki K, Ueno H, Ikeda M, Morizane C, Shimada K, Sakamoto Y, Esaki M, Saito I, Hirose H, Saito D, Sugimura H, Kosuge T, Okusaka T, Yoshida T. His595Tyr Polymorphism in the Methionine Synthase Reductase Gene Is Associated With Pancreatic Cancer Risk. Gastroenterology.2008;135:477-88.

58Ishii H, Furuse J, Kinoshita T, Konishi M, Nakagohri T, Takahashi S, Gotohda N, Nakachi K, Suzuki E, Yoshino M. Hepatectomy for hepatocellular carcinoma patients who meet the Milan criteria. Hepatogastroenterology. 2008;55:621-6.

59Ikeda M, Okusaka T, Ueno H, Morizane C, Kojima Y, Iwasa S, Hagihara A. Predictive Factors of Outcome and Tumor Response to Systemic Chemotherapy in Patients with Metastatic Hepatocellular Carcinoma. Jpn J Clin Oncol. 2008;38:675-82.

60Tanaka T, Ikeda M, Okusaka T, Ueno H, Morizane C, Hagihara A, Iwasa S, Kojima Y. Prognostic Factors in Japanese Patients with Advanced Pancreatic Cancer Treated with Single-agent Gemcitabine as First-line Therapy. Jpn J Clin Oncol. 2008;38:755-61.

61Nara S, Sano T, Ojima H, Onaya H, Ikeda M, Morizane C, Esaki M, Sakamoto Y, Shimada K, Kosuge T.Liver cryptococcosis manifesting as obstructive jaundice in a young immunocompetent man: report of a case. Surg Today.2008;38:271-4.

62Takezako Y, Okusaka T, Ueno H, Ikeda M, Morizane C, Najima M.Phase II study of cisplatin, epirubicin and continuous infusion of 5-fluorouracil in patients with advanced intrahepatic cholangiocellular carcinoma (ICC).Hepatogastroenterology. 2008;55:1380-4.

63Kim SR, Saito Y, Maekawa K, Sugiyama E, Kaniwa N, Ueno H, Okusaka T, Ikeda M, Morizane C, Yamamoto N, Yoshida T, Kamatani N, Furuse J, Ishii H, Saijo N, Ozawa S, Sawada J. Twenty novel genetic variations and haplotype structures of the DCK gene encoding human deoxycytidine kinase (dCK). Drug Metab Pharmacokinet. 2008;23(5):379-84.

7. Colorectal (Pelvic) and Urological Surgery

64Ito M, Sugito M, Kobayashi A, Nishizawa Y, Tsunoda Y, Saito N. Relationship between multiple numbers of stapler firings during rectal division and anastomotic leakage after laparoscopic rectal resection.Int J Colorectal Dis. 2008;23:703-7.

65Tsunoda Y, Ito M, Fujii H, Kuwano H, Saito N. Preoperative diagnosis of lymph node metastases of colorectal cancer by FDG-PET/CT. Jpn J Clin Oncol. 2008;38(5):347-53.

66Kosugi C, Saito N, Murakami K, Ochiai A, Koda K, Ono M, Sugito M, Ito M, Oda K, Seike K, Miyazaki M.Positron emission tomography for preoperative staging in patients with locally advanced or metastatic colorectal adenocarcinoma in lymph node metastasis.Hepatogastroenterology. 2008;55(82-83):398-402.

8. Plastic & Reconstructive Surgery

67Sakuraba M, Asano T, Miyamoto S, Hayashi R, Miyazaki M, Ugumori T, Daiko H, Kimata Y, Ebihara S, Harii K.Three-dimensional reconstruction of supraglottic structures after partial pharyngolaryngectomy for hypopharyngeal cancer.Jpn J Clin Oncol. 2008;38(6):408-13.

9. Thoracic Oncology

68Kunitoh H, Kato H, Tsuboi M, Shibata T, Asamura H, Ichinose Y, Katakami N, Nagai K, Mitsudomi, T., Matsumura A, Nakagawa K, Tada H, Saijo N, Japan Clinical Oncology Group. Phase II trial of preoperative chemoradiotherapy followed by surgical resection in patients with superior sulcus non-small-cell lung cancers: report of Japan Clinical Oncology Group trial 9806 J Clin Oncol. 2008;26:644-49.

69Naito Y, Kubota K, Nihei K, Fujii T, Yoh K, Niho S, Goto K, Ohmatsu H, Saijo N, Nishiwaki. Concurrent chemoradiotherapy with cisplatin and vinorelbine for stage III non-small cell lung cancer. J Thorac Oncol. 2008;3:617-22.

70Sekine I, Sumi M, Saijo N. Local control of regional and metastatic lesions and indication for systemic chemotherapy in patients with non-small cell lung cancer. Oncologist.2008;13S:21-7.

71Langer CJ, Wakelee H, Schiller J, Choy H, Shepherd F, Vokes EE, Adjei AA, Baas P, Saijo N, Gandara DR.Cooperative group portfolio in locally advanced non-small-cell lung cancer: are we making progress? Clin Lung Cancer. 2008;9:85-91.

72Kubota K, Kawahara M, Ogawara M, Nishiwaki Y, Komuta K, Minato K, Fujita Y, Teramukai S, Fukushima M, Furuse K; Japan Multi-National Trial Organisation.Vinorelbine plus gemcitabine followed by docetaxel versus carboplatin plus paclitaxel in patients with advanced non-small-cell lung cancer: a randomised, open-label, phase III study. Lancet Oncol.2008;9(12):1135-42.

73Sekine I, Yamamoto N, Nishio K, Saijo N.Emerging ethnic differences in lung cancer therapy. Br J Cancer. 2008;99(11):1757-62.

74Sai K, Saito Y, Sakamoto H, Shirao K, Kurose K, Saeki M, Ozawa S, Kaniwa N, Hirohashi S, Saijo N, Sawada JI.Importance of UDP-glucuronosyltransferase 1A1*6 for irinotecan toxicities in Japanese cancer patients. Cancer Lett. 2008;261:165-71.

75Saijo N, Miki T, Kubota Y, Naito S, Akaza H, Takahashi S, Minami H. Report from the second Japanese Urological Association-Japanese Society of Medical Oncology joint conference, 83.625 'diagnosis and treatment of urological malignant tumors: how can we promote subspecialists?'. Int J Urol. 2008;15:389-93.

76Sai K, Saito Y, Fukushima-Uesaka H, Kurose K, Kaniwa N, Kamatani N, Shirao K, Yamamoto N, Hamaguchi T, Kunitoh H, Ohe Y, Tamura T, Yamada Y, Minami H, Ohtsu A, Yoshida T, Saijo N, Sawada J.Impact of CYP3A4 haplotypes on irinotecan pharmacokinetics in Japanese cancer patients. Cancer Chemother Pharmacol. 2008;62(3):529-37.

77Yoh K, Nishiwaki Y, Ishii G, Goto K, Kubota K, Ohmatsu H, Niho S, Nagai K, Saijo N.Mutational status of EGFR and KIT in thymoma and thymic carcinoma. Lung Cancer. 2008;62(3):316-20.

78Kubota K, Nishiwaki Y, Tamura T, Nakagawa K, Matsui K, Watanabe K, Hida T, Kawahara M, Katakami N, Takeda K, Yokoyama A, Noda K, Fukuoka M, Saijo N. Efficacy and safety of erlotinib monotherapy for Japanese patients with advanced non-small cell lung cancer: a phase II study. J Thorac Oncol.2008;3(12):1439-45.

79Maruyama R, Nishiwaki Y, Tamura T, Yamamoto N, Tsuboi M, Nakagawa K, Shinkai T, Negoro S, Imamura F, Eguchi K, Takeda K, Inoue A, Tomii K, Harada M, Masuda N, Jiang H, Itoh Y, Ichinose Y, Saijo N, Fukuoka M.Phase III study, V-15-32, of gefitinib versus docetaxel in previously treated Japanese patients with non-small-cell lung cancer. J Clin Oncol.2008;26(26):4244-52.

80Kudoh S, Kato H, Nishiwaki Y, Fukuoka M, Nakata K, Ichinose Y, Tsuboi M, Yokota S, Nakagawa K, Suga M; Japan Thoracic Radiology Group, Jiang H, Itoh Y, Armour A, Watkins C, Higenbottam T, Nyberg F.Interstitial lung disease in Japanese patients with lung cancer: a cohort and nested case-control study.Am J Respir Crit Care Med. 2008;177:1348-57.

81Suzuki Y, Tokuda Y, Fujiwara Y, Minami H, Ohashi Y, Saijo N. Weekly epoetin beta maintains haemoglobin levels and improves quality of life in patients with non-myeloid malignancies receiving chemotherapy.Jpn J Clin Oncol. 2008;38:214-21.

82Kiura K, Nakagawa K, Shinkai T, Eguchi K, Ohe Y, Yamamoto N, Tsuboi M, Yokota S, Seto T, Jiang H, Nishio K, Saijo N, Fukuoka M.A randomized, double-blind, phase IIa dose-finding study of Vandetanib (ZD6474) in Japanese patients with non-small cell lung cancer.J Thorac Oncol. 2008;3:386-93.

83Nakagawa K, Yamazaki K, Kunitoh H, Hida T, Gemba K, Shinkai T, Ichinose Y, Adachi S, Nambu Y, Saijo N, Fukuoka M.Efficacy and safety of pemetrexed in combination with cisplatin for malignant pleural mesothelioma: a phase I/II study in Japanese patients. Jpn J Clin Oncol. 2008;38(5):339-46.

84Ohe Y, Ichinose Y, Nakagawa K, Tamura T, Kubota K, Yamamoto N, Adachi S, Nambu Y, Fujimoto T, Nishiwaki Y, Saijo N, Fukuoka M. Efficacy and safety of two doses of pemetrexed supplemented with folic acid and vitamin B12 in previously treated patients with non-small cell lung cancer.Clin Cancer Res. 2008;14(13):4206-12.

85Sekine I, Nokihara H, Takeda K, Nishiwaki Y, Nakagawa K, Isobe H, Mori K, Matsui K, Saijo N, Tamura T.Randomised phase II trial of irinotecan plus cisplatin vs irinotecan, cisplatin plus etoposide repeated every 3 weeks in patients with extensive-disease small-cell lung cancer. Br J Cancer. 2008;98(4):693-6.

86Niho S, Kubota K, Yoh K, Goto K, Ohmatsu H, Nihei K, Saijo N, Nishiwaki Y. Clinical outcome of chemoradiation therapy in patients with limited-disease small cell lung cancer with ipsilateral pleural effusion. J Thorac Oncol. 2008;3(7):723-7.

87Kim YH, Goto K, Yoh K, Niho S, Ohmatsu H, Kubota K, Saijo N, Nishiwaki Y. Performance status and sensitivity to first-line chemotherapy are significant prognostic factors in patients with recurrent small cell lung cancer receiving second-line chemotherapy. Cancer. 2008;113(9):2518-23.

88Kawai O, Ishii G, Kubota K, Murata Y, Naito Y, Mizuno T, Aokage K, Saijo N, Nishiwaki Y, Gemma A, Kudoh S, Ochiai A. Predominant infiltration of macrophages and CD8(+) T Cells in cancer nests is a significant predictor of survival in stage IV nonsmall cell lung cancer.Cancer.2008;113(6):1387-95.

89Kenmotsu H, Ishii G, Nagai K, Nakao M, Kawase A, Kojika M, Murata Y, Nishiwaki Y, Ochiai A.Pleomorphic carcinoma of the lung expressing podoplanin and calretinin. Pathol Int. 2008;58(12):771-4.

90Akechi T, Okamura H, Okuyama T, Furukawa TA, Nishiwaki Y, Uchitomi Y. Psychosocial factors and survival after diagnosis of inoperable non-small cell lung cancer.Psychooncology.2008;18(1):23-9.

10. Thoracic Surgery

91Hishida T, Yoshida J, Nishimura M, Nishiwaki Y, Nagai K.Problems in the current diagnostic standards of clinical N1 non-small cell lung cancer. Thorax. 2008;63:526-31.

92Aokage K, Yoshida J, Ishii G, Takahashi S, Sugito M, Nishimura M, Ochiai A, Nagai K. Long-term survival in two cases of resected gastric metastasis of pulmonary pleomorphic carcinoma.J Thorac Oncol.2008;3(7):796-9.

93Kawase A, Ishii G, Nagai K, Ito T, Nagano T, Murata Y, Hishida T, Nishimura M, Yoshida J, Suzuki K, Ochiai A.Podoplanin expression by cancer associated fibroblasts predicts poor prognosis of lung adenocarcinoma.Int J Cancer. 2008;123(5):1053-9.

94Mochizuki T, Ishii G, Nagai K, Yoshida J, Nishimura M, Mizuno T, Yokose T, Suzuki K, Ochiai A. Pleomorphic carcinoma of the lung: clinicopathologic characteristics of 70 cases. Am J Surg Pathol. 2008; 32(11):1727-35.

95Mizuno T, Ishii G, Nagai K, Yoshida J, Nishimura M, Mochizuki T, Kawai O, Hasebe T, Ochiai A. Identification of a low risk subgroup of stage IB lung adenocarcinoma patients. Lung Cancer. 2008;62(3):302-8.

11. Pathology Division

96Chiba H, Ishii G, Ito TK, Aoyagi K, Sasaki H, Nagai K, Ochiai A. CD105-positive cells in pulmonary arterial blood of adult human lung cancer patients include mesenchymal progenitors.Stem Cells.2008;26(10):2523-30.

97Hoshino A, Chiba H, Nagai K, Ishii G, Ochiai A.Human vascular adventitial fibroblasts contain mesenchymal stem/progenitor cells. Biochem Biophys Res Commun. 2008;368:305-10.

98Atsumi N, Ishii G, Kojima M, Sanada M, Fujii S, Ochiai A.Podoplanin, a novel marker of tumor-initiating cells in human squamous cell carcinoma A431. Biochem Biophys Res Commun. 2008;373(1):36-41.

99Kojima M, Ishii G, Atsumi N, Fujii S, Saito N, Ochiai A. Immunohistochemical detection of CD133 expression in colorectal cancer: a clinicopathological study. Cancer Sci. 2008;99(8):1578-83.

100Fujii S, Ito K, Ito Y, Ochiai A. Enhancer of zeste homologue 2 (EZH2) down-regulates RUNX3 by increasing histone H3 methylation. J Biol Chem. 2008; 283(25):17324-32.

101Fujii S, Ochiai A.Enhancer of zeste homolog 2 downregulates E-cadherin by mediating histone H3 methylation in gastric cancer cells. Cancer Sci. 2008; 99:738-46.

102Hofmann M, Stoss O, Shi D, Bu¨ttner R, van de Vijver M, Kim W, Ochiai A, Ru¨schoff J, Henkel T. Assessment of a HER2 scoring system for gastric cancer: results from a validation study.Histopathology. 2008;52:797-805.

103Yamada A, Sasaki H, Aoyagi K, Sano M, Fujii S, Daiko H, Nishimura M, Yoshida T, Chiba T, Ochiai A. Expression of cytokeratin 7 predicts survival in stage I/IIA/IIB squamous cell carcinoma of the esophagus.Oncol Rep.2008;20(5):1021-7.

104Fujii S, Mitsunaga S, Yamazaki M, Hasebe T, Ishii G, Kojima M, Kinoshita T, Ueno T, Esumi H, Ochiai A. Autophagy is activated in pancreatic cancer cells and correlates with poor patient outcome. Cancer Sci. 2008;99(9):1813-9.

105Yamazaki M, Fujii S, Daiko H, Hayashi R, Ochiai A. Carcinoma showing thymus-like differentiation (CASTLE) with neuroendocrine differentiation. Pathol Int. 2008;58(12):775-9.

106Hasebe T, Yamauchi C, Iwasaki M, Ishii G, Wada N, Imoto S. Grading system for lymph vessel tumor emboli for prediction of the outcome of invasive ductal carcinoma of the breast.Hum Pathol. 2008;39:427-36.

107Sentani K, Oue N, Tashiro T, Sakamoto N, Nishisaka T, Fukuhara T, Taniyama K, Matsuura H, Arihiro K, Ochiai A, Yasui W. Immunohistochemical staining of Reg IV and claudin-18 is useful in the diagnosis of gastrointestinal signet ring cell carcinoma. Am J Surg Pathol. 2008;32(8):1182-9.

108Yanagihara K, Takigahira M, Tanaka H, Arao T, Aoyagi Y, Oda T, Ochiai A, Nishio K. Establishment and molecular profiling of a novel human pancreatic cancer panel for 5-FU.Cancer Sci. 2008;99(9):1859-64.

109Sangai T, Fujimoto H, Miyamoto S, Maeda H, Nakamura M, Ishii G, Nagai K, Nagashima T, Miyazaki M, Ochiai A. Roles of osteoclasts and bone-derived IGFs in the survival and growth of human breast cancer cells in human adult bone implanted into nonobese diabetic/severe combined immunodeficient mice. Clin Exp Metastasis. 2008;25:401-410.

12. Investigative Treatment Division

110Matsumura Y.Poly (amino acid) micelle nanocarriers in preclinical and clinical studies.Adv Drug Deliv Rev. 2008;60:899-914.

111Matsumura Y.Polymeric micellar delivery systems in oncology.Jpn J Clin Oncol. 2008;38(12):793-802.

112Saito Y, Yasunaga M, Kuroda J, Koga Y, Matsumura Y. Enhanced distribution of NK012 and prolonged sustained-release of SN-38 within tumors are the key strategic point for a hypovascular tumor. Cancer Sci. 2008;99:1258-64.

113Sumitomo M, Koizumi F, Asano T, Horiguchi A, Ito K, Asano T, Kakizoe T, Hayakawa M, Matsumura Y. Novel SN-38-incorparated polymeric micelles, NK012, strongly supperss renal cancer progression. Cancer Res. 2008;68:1631-5.

114Nakajima TE, Yanagihara K, Takigahira M, Yasunaga M, Kato K, Hamaguchi T, Yamada Y, Shimada Y, Mihara K, Ochiya T, Matsumura Y.Antitumor effect of SN-38-releasing polymeric micelles, NK012, on spontaneous peritoneal metastases from orthotopic gastric cancer in mice compared with irinotecan.Cancer Res. 2008;68(22):9318-22.

115Suzuki R, Takizawa T, Negishi Y, Utoguchi N, Sawamura K, Tanaka K, Namai E, Oda Y, Matsumura Y, Maruyama K.Tumor specific ultrasound enhanced gene transfer in vivo with novel liposomal bubbles.J Control Release. 2008;125(2):137-44.

116Watanabe Y, Aoi A, Horie S, Tomita N, Mori S, Morikawa H, Matsumura Y, Vassaux G, Kodama T.Low-intensity ultrasound and microbubbles enhance the antitumor effect of cisplatin. Cancer Sci.2008;99(12):2525-31.

117Onouchi S, Matsushita H, Moriya Y, Akasu T, Fujita S, Yamamoto S, Hasegawa H, Kitagawa Y, Matsumura Y. New method for colorectal cancer diagnosis based on SSCP analysis of DNA from exfoliated colonocytes in naturally evacuated feces. Anticancer Res. 2008;28(1A):145-50.

118Koga Y, Yasunaga M, Katayose S, Moriya Y, Akasu T, Fujita S, Yamamoto S, Baba H, Matsumura Y.Improved recovery of exfoliated colonocytes from feces using newly developed immunomagnetic beads.Gastroenterol Res Pract. 2008;2008:605273.

119Koga Y, Yasunaga M, Moriya Y, Akasu T, Fujita S, Yamamoto S, Kozu T, Baba H, Matsumura Y.Detection of colorectal cancer cells from feces using quantitative real-time RT-PCR for colorectal cancer diagnosis. Cancer Sci.2008;99(10):1977-83.

120Nakajima TE, Yasunaga M, Kano Y, Koizumi F, Kato K, Hamaguchi T, Yamada Y, Shirao K, Shimada Y, Matsumura Y. Synergistic antitumor activity of the novel SN-38-incorporating polymeric micelles, NK012, combined with 5-fluorouracil in a mouse model of colorectal cancer, as compared with that of irinotecan plus 5-fluorouracil. Int J Cancer. 2008;122(9):2148-53.

121Yajima S, Ishii M, Matsushita H, Aoyagi K, Yoshimatsu K, Kaneko H, Yamamoto N, Teramoto T, Yoshida T, Matsumura Y, Sasaki H. Expression profiling of fecal colonocytes for RNA-based screening of colorectal cancer. Int J Oncol. 2008;31:1029-37.

13. Cancer Physiology Project

122Win NN, Awale S, Esumi H, Tezuka Y, Kadota S.Panduratins D-I, novel secondary metabolites from rhizomes of Boesenbergia pandurata. Chem Pharm Bull (Tokyo)2008;56:491-6.

123Awale S, Li F, Onozuka H, Esumi H, Tezuka Y, Kadota S.Constituents of Brazilian red propolis and their preferential cytotoxic activity against human pancreatic PANC-1cancer cell line in nutrient-deprived condition.Bioorg Med Chem. 2008;16:181-9.

124Win NN, Awale S, Esumi H, Tezuka Y, Kadota S. Novel anticancer agents, kayeassamins C-I from the flower of Kayea assamica of Myanmar.Bioorg Med Chem. 2008;16(18):8653-60.

125Win NN, Awale S, Esumi H, Tezuka Y, Kadota S. Novel anticancer agents, kayeassamins A and B from the flower of Kayea assamica of Myanmar. Bioorg Med Chem.2008;18(16):4688-91.

126Nakamura M, Esumi H, Jin L, Mitsuya H, Hata H.Induction of necrosis in human myeloma cells by kigamicin. Anticancer Res. 2008;28:37-43.

127Mykhalchenko VG, Minchenko DO, Tsuchihara K, Moenner M, Komisarenko SV, Bikfalvi A, Esumi H, Minchenko OH.Expression of mouse 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 mRNA alternative splice variants in hypoxia. Ukr Biokhim Zh. 2008; 80(1):19-25.

128Minchenko DO, Mykhalchenko VG, Tsuchihara K, Kanehara S, Yavorovsky OP, Zavgorodny IV, Paustovsky YO, Komisarenko SV, Esumi H, Minchenko OH. Alternative splice variants of rat 6-phosphofructo-2-kinase/ fructose-2,6-bisphosphatase-4 mRNA. Ukr Biokhim Zh.2008;80(4):66-73.

129Kuga W, Tsuchihara K, Ogura T, Kanehara S, Saito M, Suzuki A, Esumi H. Nuclear localization of SNARK; its impact on gene expression. Biochem Biophys Res Commun. 2008;377(4):1062-6.

130Tsuchihara K, Ogura T, Fujioka R, Fujii S, Kuga W, Saito M, Ochiya T, Ochiai A, Esumi H. Susceptibility of Snark-deficient mice to azoxymethane-induced colorectal tumorigenesis and the formation of aberrant crypt foci.Cancer Sci. 2008;99:677-82.

131Sugiyama K, Ishii G, Ochiai A, Esumi H.Improvement of the breaking strength of wound by combined treatment with recombinant human G-CSF, recombinant human M-CSF, and a TGF-beta1 receptor kinase inhibitor in rat skin. Cancer Sci.2008;99:1021-8.

132Tomasini R, Tsuchihara K, Wilhelm M, Fujitani M, Rufini A, Cheung CC, Khan F, Itie-Youten A, Wakeham A, Tsao MS, Iovanna JL, Squire J, Jurisica I, Kaplan D, Melino G, Jurisicova A, Mak TW.TAp73 knockout shows genomic instability with infertility and tumor suppressor functions.Genes Dev. 2008;22(19):2677-91.

14. Cancer Immunotherapy Project

133Motomura Y, Ikuta Y, Kuronuma T, Komori H, Ito M, Tsuchihara M, Tsunoda Y, Shirakawa H, Baba H, Nishimura Y, Kinoshita T, Nakatsura T.HLA-A2 and =-#REF!-restricted glypican-3-derived peptide vaccine induce specific ctls: preclinical study using mice. int j oncol. 2008;32:985-90.

134Muchemwa F.C, Nakatsura T, Fukushima S, Nishimura Y, Kageshita T, Ihn H. Differential Expression of Heat Shock Protein 105 in Melanoma and Melanocytic Naevi. Melanoma Res.2008;18:166-171.

135Harao M, Hirata S, Irie A, Senju S, Nakatsura T, Komori H, Ikuta Y, Yokomine K, Imai K, Inoue M, Harada K, Mori T, Tsunoda T, Nakatsuru S, Daigo Y, Nomori H, Nakamura Y, Baba H, Nishimura Y. HLA-A2-restricted CTL epitopes of a novel lung cancer-associated cancer testis antigen, cell division cycle associated 1, can induce tumor-reactive CTL.Int J Cancer. 2008;123(11):2616-25.

15. Functional Imaging Division

136Inoue K, Sato T, Kitamura H, Ito M, Tsunoda Y, Hirayama A, Kurosawa H, Tanaka T, Fukushi M, Moriyama N, Fujii H.Improvement of the diagnostic accuracy of lymph node metastases of colorectal cancer in 18F-FDG-PET/CT by optimizing the iteration number for the image reconstruction. Ann Nucl Med.2008; 22(6):465-73.

137Inoue K, Sato T, Kitamura H, Ito M, Tsunoda Y, Hirayama A, Kurosawa H, Tanaka T, Fukushi M, Moriyama N, Fujii H. Diagnosis supporting algorithm for lymph node metastases from colorectal carcinoma on 18F-FDG PET/CT. Ann Nucl Med. 2008;22(1):41-8.

138Suzuki C, Jacobsson H, Hatschek T, Torkzad MR, Bode´n K, Eriksson-Alm Y, Berg E, Fujii H, Kubo A, Blomqvist L. Radiologic measurements of tumor response to treatment: practical approaches and limitations.Radiographics. 2008;28(2):329-44.

139Takeda A, Kunieda E, Takeda T, Tanaka M, Sanuki N, Fujii H, Shigematsu N, Kubo A.Possible Misinterpretation of Demarcated Solid Patterns of Radiation Fibrosis on CT Scans as Tumor Recurrence in Patients Receiving Hypofractionated Stereotactic Radiotherapy for Lung Cancer. Int J Radiat Oncol Biol Phys. 2008;70(4):1057-65.

140Nakahara T, Kitagawa Y, Takeuchi H, Fujii H, Suzuki T, Mukai M, Kitajima M, Kubo A.Preoperative lymphoscintigraphy for detection of sentinel lymph node in patients with gastric cancer--initial experience. Ann Surg Oncol. 2008;15(5):1447-53.

141Tomifuji M, Shiotani A, Fujii H, Araki K, Saito K, Inagaki K, Mukai M, Kitagawa Y, Ogawa K.Sentinel node concept in clinically n0 laryngeal and hypopharyngeal cancer.Ann Surg Oncol.2008;15(9):2568-75.

16. Psycho-Oncology Division

142 Motohashi N, Shioe K, Nakamura J, Ohshima A, Yamada K, Ozawa H, Someya T, Uchitomi Y, Higuchi T.Revised psychopharmacological algorithms for the treatment of mood disorders in Japan. Int J Psychiatry Clin Pract. 2008;12:11-18.

143Okamura M, Akizuki N, Nakano T, Shimizu K, Ito T, Akechi T and Uchitomi Y. Clinical experience of the use of a pharmacological treatment algorithm for major depressive disorder in patients with advanced cancer. Psychooncology. 2008;17:154-60.

144Shimizu K, Akizuki N, Akechi T, Okamura M, Oba A, Shimamoto M, Inagaki M, Uchitomi Y. Clinical experience of the modified nurse-assisted screening and psychiatric referral program. Palliat Support Care. 2008; 6:29-32.

145Hamaguchi T, Okamura H, Nakaya N, Abe K, Abe Y, Umezawa S, Kurihara M, Nakaya K, Yomiya K, Uchitomi Y.Survey of the current status of cancer rehabilitation in Japan. Disabil Rehabil. 2008;30:559-64.

146Miyashita M, Morita T, Sato K, Hirai K, Shima Y, Uchitomi Y. Good Death Inventory: A Measure for Evaluating Good Death from the Bereaved Family Member's Perspective. Pain Symptom Manage.2008;35:486-98.

147Sato K, Miyashita M, Morita T, Sanjo M, Shima Y, Uchitomi Y. Quality of end-of-life treatment for cancer patients in general wards and the palliative care unit at a regional cancer center in Japan: a retrospective chart review. Support Care Cancer. 2008;16:113-22.

148Shiozaki M, Hirai K, Dohke R, Morita T, Miyashita M, Sato K, Tsuneto S, Shima Y and Uchitomi Y.Measuring the regret of bereaved family members regarding the decision to admit cancer patients to palliative care units. Psychooncology. 2008;17:926-31.

149Sato K, Miyashita M, Morita T, Sanjo M, Shima Y and Uchitomi Y. Reliability assessment and findings of a newly developed quality measurement instrument: quality indicators of end-of-life cancer care from medical chart review at a Japanese regional cancer center.J Palliat Med.2008;11:729-37.

150Miyashita M, Hirai K, Morita T, Sanjo M and Uchitomi Y.Barriers to referral to inpatient palliative care units in Japan: a qualitative survey with content analysis. Support Care Cancer. 2008;16:217-22.

151Miyashita M, Morita T, Sato K, Hirai K, Shima Y and Uchitomi Y.Factors contributing to evaluation of a good death from the bereaved family member's perspective. Psychooncology. 2008;17612-620.

152Sanjo M, Miyashita M, Morita T, Hirai K, Kawa M, Ashiya T, Ishihara T, Miyoshi I, Matsubara T, Nakaho T, Nakashima N, Onishi H, Ozawa T, Suenaga K, Tajima T, Hisanaga T and Uchitomi Y.Perceptions of specialized inpatient palliative care: a population-based survey in Japan. J Pain Symptom Manage. 2008;35:275-82.

153Asai M, Akechi T, Nakano T, Shimizu K, Umezawa S, Akizuki N and Uchitomi Y. Psychiatric disorders and background characteristics of cancer patients' family members referred to psychiatric consultation service at National Cancer Center Hospitals in Japan. Palliat Support Care. 2008;6:225-30.

154Hirai K, Shiozaki M, Motooka H, Arai H, Koyama A, Inui H, Uchitomi Y. Discrimination between worry and anxiety among cancer patients: development of a Brief Cancer-Related Worry Inventory. Psychooncology. 2008;17(12):1172-9.

155Okuyama T, Akechi T, Shima Y, Sugahara Y, Okamura H, Hosaka T, Furukawa TA, Uchitomi Y. Factors Correlated with Fatigue in Terminally Ill Cancer Patients: A Longitudinal Study. J Pain Symptom Manage. 2008;35:515-23.

156Inagaki M, Isono M, Okuyama T, Sugawara Y, Akechi T, Akizuki N, Fujimori M, Mizuno M, Shima Y, Kinoshita H and Uchitomi Y.Plasma interleukin-6 and fatigue in terminally ill cancer patients. J Pain Symptom Manage. 2008;35:153-61.

157Saito-Nakaya K, Nakaya N, Akechi T, Inagaki M, Asai M, Goto K, Nagai K, Nishiwaki Y, Tsugane S, Fukudo S and Uchitomi Y.Marital status and non-small cell lung cancer survival: the Lung Cancer Database Project in Japan.Psychooncology. 2008;17:869-76.

158Nakaya N, Saito-Nakaya K, Akechi T, Kuriyama S, Inagaki M, Kikuchi N, Nagai K, Tsugane S, Nishiwaki Y, Tsuji I, Uchitomi Y. Negative psychological aspects and survival in lung cancer patients. Psychooncology. 2008;17: 466-73.

159Hara E, Matsuoka Y, Hakamata Y, Nagamine M, Inagaki M, Imoto S, Murakami K, Kim Y and Uchitomi Y. Hippocampal and amygdalar volumes in breast cancer survivors with posttraumatic stress disorder. J Neuropsychiatry Clin Neurosci. 2008;20:302-8.

160 Yamashita M, Okamura H, Murakami Y, Sugano K, Yoshida T, Uchitomi Y. Psychological impact and associated factors after disclosure of genetic test results concerning hereditary non-polyposis colorectal cancer. Stress and Health 2008;24:407-412.

17. Particle Therapy and Radiation Oncology Division

161Nakamura K, Mizowaki T, Imada H, Karasawa K, Uno T, Onishi H, Nihei K, Sasaki S, Ogura M, Akimoto T.External-beam radiotherapy for localized or locally advanced prostate cancer in Japan: a multi-institutional outcome analysis.Jpn J Clin Oncol. 2008;38:200-4.

162 Nishio T, Miyatake A, Inoue K, Gomi-Miyagishi T, Kohno R, Kameoka S, Nakagawa K, Ogino T.Experimental verification of proton beam monitoring in a human body by use of activity image of positron-emitting nuclei generated by nuclear fragmentation reaction. Radiol Phys Technol. 2008;1:44-54.

163 Kohno R, Hirano E, Nishio T, Miyagashi T, Goka T, Kawashima M, Ogino T. Dosimetric evaluation of a MOSFET detector for clinical application in photon therapy. Radiol Phys Technol.2008;1:55-61.

164 Kameoka S, Amako K, Iwai G, Murakami K, Sasaki T, Toshito T, Yamashita T, Aso T, Kimura A, Kanai T, Kanematsu N, Komori M, Takei Y, Yonai S, Tashiro M, Koikegami H, Tomita H, Koi T. Dosimetric evaluation of nuclear interaction models in the Geant4 Monte Carlo simulation toolkit for carbon-ion radiotherapy. Radiol Phys Technol. 2008;1:183-7.

165 Himukai T, Takada Y, Hotta K, Hara Y, Komori M, Kanai T, Kohno R. Analytical design method of optimal ridge filters for wobbled and collimated proton beams.Jpn J Med Phys.2008;28:57-69.


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