National Cancer Center

Cumulated List of Papers Published in This Year



1. Breast Surgery
2. Diagnostic Radiology
3. Endoscopy & Gastrointestinal Oncology
4. Head and Neck Surgery
5. Hematology & Oncology
6. Gastric, Hepatobiliary & Pancreatic Surgery
7. Hepatobiliary & Pancreatic Oncology
8. Colorectal (Pelvic) and Urological Surgery
9. Plastic & Reconstructive Surgery
10. Thoracic Oncology and Surgery
11. Pathology Division
12. Investigative Treatment Division
13. Cancer Physiology Project
14. Cancer Immunotherapy Project
15. Functional imaging division
16. Psycho-Oncology Division
17. Particle Therapy and Radiation Oncology Division

1 . Breast Surgery

1 . Imoto S, Wada N, Hasebe T, Ochiai A, Kitoh T. Serum c-erbB-2 protein is a useful marker for monitoring tumor recurrence of the breast. Int J Cancer, 120:357-361, 2007

2 . Wada N, Sakemura N, Imoto S, Hasebe T, Ochiai A, Moriyama N. Sentinel node biopsy in primary breast cancer: radioactive detection and metastatic disease. Eur J Surg Oncol, 33:691-695, 2007

2 . Diagnostic Radiology

3 . Endoscopy & Gastrointestinal Oncology

1 . Boku N, Ohtsu A, Yoshida S, Shirao K, Shimada Y, Hyodo I, Saito H, Miyata Y. Significance of Biological Markers for Predicting Prognosis and Selecting Chemotherapy Regimens of Advanced Gastric Cancer Patients between Continuous Infusion of 5-FU and a Combination of 5-FU and Cisplatin. Jpn J Clin Oncol, 37:275-281, 2007

2 . Horimatsu T, Fu KI, Sano Y, Yano T, Saito Y, Matsuda T, Fujimori T, Yoshida S. Acute appendicitis as a rare complication after endoscopic mucosal resection. Dig Dis Sci, 52:1741-1744, 2007

3 . Asakage T, Yokoyama A, Haneda T, Yamazaki M, Muto M, Yokoyama T, Kato H, Igaki H, Tsujinaka T, Kumagai Y, Yokoyama M, Omori T, Watanabe H. Genetic Polymorphisms of alcohol and aldehyde dehydrogenases, and drinking, smoking and diet in Japanese men with oral and pharyngeal squamous cell carcinoma. Carcinogenesis, 28:865-874, 2007

4 . Oyama Y, Isse T, Ogawa M, Muto M, Uchiyama I, Kawamoto T. Susceptibility to inhalation toxicity of acetaldehyde in Aldh2 knockout mice. Front Biosci, 12:1927-1934, 2007

5 . Fuse N, Doi T, Ohtsu A, Takeuchi S, Kojima T, Taku K, Tahara M, Muto M, Asaka M, Yoshida S. Feasibility of Oxaliplatin and Infusional Fluorouracil/Leucovorin (FOLFOX4) for Japanese Patients with Unresectable Metastatic Colorectal Cancer. Jpn J Clin Oncol, 37:434-439, 2007

6 . Boku N, Ohtsu A, Hyodo I, Shirao K, Miyata Y, Nakagawa K, Tamura T, Hatake K, Tanigawara Y. Phase II Study of Oxaliplatin in Japanese Patients with Metastatic Colorectal Cancer Refractory to Fluoropyrimidines. Jpn J Clin Oncol, 37:440-445, 2007

7 . Kawashima M, Hayashi R, Tahara M, Yamazaki M, Miyazaki M, Arahira S, Ogino T. Accelerated Radiotherapy and Larynx Preservation in Favorable-risk Patients with T2 or Worse Hypopharyngeal Cancer. Jpn J Clin Oncol, 37: 345-352, 2007

8 . Kawada K, Murakami K, Sato T, Kojima Y, Ebi H, Mukai H, Tahara M, Shimokata K, Minami H. Prospective Study of Positron Emission Tomography for Evaluation of the Activity of Lapatinib, a Dual Inhibitor of the ErbB1 and ErbB2 Tyrosine Kinases, in Patients with Advanced Tumors. Jpn J Clin Oncol , 37:44-48, 2007

9 . Kawashima M, Fujii H, Hayashi R, Tahara M, Nasu K, Arahira S, Ogino T. Influence of delayed tumor clearance on reliability of complete response rate in chemoradiotherapy for head and neck cancer. Jpn J Clin Oncol , 37:559-567, 2007

10 . Maekawa K, Saeki M, Saito Y, Ozawa S, Kurose K, Kaniwa N, Kawamoto M, Kamatani N, Kato K, Hamaguchi T, Yamada Y, Shirao K, Shimada Y, Muto M, Doi T, Ohtsu A, Yoshida T, Matsumura Y, Saijo N, Sawada J. Genetic variations and haplotype structures of the DPYD gene encoding dihydropyrimidine dehydrogenase in Japanese and their ethnic differences. J Hum Genet, 52:804-819, 2007

11 . Boku N, Ohtsu A, Nagashima F, Shirao K, Koizumi W. Relationship between Expression of Vascular Endothelial Growth Factor in Tumor Tissue from Gastric Cancers and Chemotherapy Effects: Comparison between S-1 alone and the Combination of S-1 plus CDDP. Jpn J Clin Oncol, 37:509-514, 2007

12 . Hosokawa A, Sugiyama T, Ohtsu A, Doi T, Hattori S, Kojima T, Yano T, Minashi K, Muto M, Yoshida S. Long-term outcomes of patients with metastatic gastric cancer after initial S-1 monotherapy. J Gastroenterol, 42:533-538, 2007

13 . Kim SR, Sai K, Tanaka-Kagawa T, Jinno H, Ozawa S, Kaniwa N, Saito Y, Akasawa A, Matsumoto K, Saito H, Kamatani N, Shirao K, Yamamoto N, Yoshida T, Minami H, Ohtsu A, Saijo N, Sawada J. Haplotypes and a Novel Defective Allele of CES2 Found in a Japanese Population. Drug Metab Dispos, 35:1865-1872, 2007

14 . Minami H, Sai K, Saeki M, Saito Y, Ozawa S, Suzuki K, Kaniwa N, Sawada J, Hamaguchi T, Yamamoto N, Shirao K, Yamada Y, Ohmatsu H, Kubota K, Yoshida T, Ohtsu A, Saijo N. Irinotecan pharmacokinetics/pharmacodynamics and UGT1A genetic polymorphisms in Japanese: roles of UGT1A1*6 and *28. Pharmacogenet Genomics, 17:497-504, 2007

4 . Head and Neck Surgery

1 . Daiko H, Hayashi R, Saikawa M, Sakuraba M, Yamazaki M, Miyazaki M, Ugumori T, Asai M, Oyama W, Ebihara S. Surgical management of carcinoma of the cervical esophagus. J Surg Oncol, 96:166-172, 2007

5 . Hematology & Oncology

1 . Nakajima M, Komagata S, Fujiki Y, Kanada Y, Ebi H, Itoh K, Mukai H, Yokoi T, Minami H. Genetic polymorphisms of CYP2B6 affect the pharmacokinetics/pharmacodynamics of cyclophosphamide in Japanese cancer@patients. Pharmacogenet and Genomics, 17:431-445, 2007

2 . Sugisaki K, Itoh K, Tamaru J. Acquired C1-esterase inhibitor deficiency and positive lupus anticoagulant accompanied by splenic marginal zone B-cell lymphoma. Clin Exp Rheumatol, 25:627-629, 2007

6 . Gastric, Hepatobiliary & Pancreatic Surgery

1 . Takahashi S, Nagai K, Saito N, Konishi M, Nakagohri T, Gotohda N, Nishimura M, Yoshida J, Kinoshita T. Multiple resections for hepatic and pulmonary metastases of colorectal carcinoma. Jpn J Clin Oncol, 37:186-192, 2007

2 . Konishi M, Kinoshita T, Nakagohri T, Takahashi S, Gotohda N, Ryu M. Pancreas-sparing duodenectomy for duodenal neoplasms including malignancies. Hepatogastroenterology, 54:753-757, 2007

3 . Nakagohri T, Kinoshita T, Konishi M, Takahashi S, Tanizawa Y. Clinical results of extended lymphadenectomy and intraoperative radiotherapy for pancreatic adenocarcinoma. Hepatogastroenterology, 54:564-569, 2007

4 . Kobayashi A, Takahashi S, Ishii H, Konishi M, Nakagohri T, Gotohda N, Satake M, Furuse J, Kinoshita T. Factors predicting survival in advanced T-staged hepatocellular carcinoma patients treated with reduction hepatectomy followed by transcatheter arterial chemoembolization. Eur J Surg Oncol, 33:1019-1024, 2007

7 . Hepatobiliary & Pancreatic Oncology

1 . Ikeda M, Okusaka T, Ito Y, Ueno H, Morizane C, Furuse J, Ishii H, Kawashima M, Kagami Y, Ikeda H. A phase I trial of S-1 with concurrent radiotherapy for locally advanced pancreatic cancer. Br J Cancer, 96:1650-1655, 2007

2 . Nakachi K, Furuse J, Ishii H, Suzuki E, Yoshino M. Prognostic factors in patients with gemcitabine-refractory pancreatic cancer. Jpn J Clin Oncol, 37:114-120, 2007

3 . Kobayashi A, Takahashi S, Ishii H, Konishi M, Nakagohri T, Gotohda N, Satake M, Furuse J, Kinoshita T. Factors predicting survival in advanced T-staged hepatocellular carcinoma patients treated with reduction hepatectomy followed by transcatheter arterial chemoembolization. Eur J Surg Oncol, 33:1019-1024, 2007

4 . Furuse J, Ishii H, Kawashima M, Nagase M, Nakachi K, Ogino T, Yoshino M. A phase I study of hypofractionated radiotherapy followed by systemic chemotherapy with full-dose gemcitabine in patients with unresectable locally advanced pancreatic cancer. Hepatogastroenterology, 54:1575-1578, 2007

5 . Furuse J, Ishii H, Nakachi K, Suzuki E, Shimizu S, Yoshino M. Research adovances in chemotherapy for pancreatic cancer in Japan. Res Adv in Gastroenterology, 1:11-18, 2007

8 . Colorectal (Pelvic) and Urological Surgery

1 . Seike K, Koda K, Saito N, Oda K, Kosugi C, Shimizu K, Miyazaki M. Laser Doppler assessment of the influence of division at the root of the inferior mesenteric artery on anastomotic blood flow in rectosigmoid cancer surgery. Int J Colorectal Dis, 22:689-697, 2007

2 . Takahashi S, Nagai K, Saito N, Konishi M, Nakagohri T, Gotohda N, Nishimura M, Yoshida J, Kinoshita T. Multiple resections for hepatic and pulmonary metastases of colorectal carcinoma. Jpn J Clin Oncol, 37:186-192, 2007

3 . Saito N, Suzuki T, Sugito M, Ito M, Kobayashi A, Tanaka T, Kotaka M, Karaki H, Kobatake T, Tsunoda Y, Shiomi A, Yano M, Minagawa N, Nishizawa Y. Bladder-sparing extended resection of locally advanced rectal cancer involving the prostate and seminal vesicles. Surg Today, 37:845-852, 2007

4 . Kobayashi A, Sugito M, Ito M, Saito N. Predictors of successful salvage surgery for local pelvic recurrence of rectosigmoid colon and rectal cancers. Surg Today, 37:853-859, 2007

5 . Fujita S, Saito N, Yamada T, Takii Y, Kondo K, Ohue M, Ikeda E, Moriya Y. Randomized, multicenter trial of antibiotic prophylaxis in elective colorectal surgery: single dose vs 3 doses of a second-generation cephalosporin without metronidazole and oral antibiotics. Arch Surg, 142:657-661, 2007

9 . Plastic & Reconstructive Surgery

1 . Sarukawa S, Sakuraba M, Asano T, Yano T, Kimata Y, Hayashi R, Ebihara S. Immediate maxillary reconstruction after malignant tumor extirpation. Eur J Surg Oncol, 33:518-523, 2007

10 . Thoracic Oncology and Surgery

1 . Yoh K, Niho S, Goto K, Ohmatsu H, Kubota K, Kakinuma R, Saijo N, Nishiwaki Y. Randomized trial of drip infusion versus bolus injection of vinorelbine for the control of local venous toxicity. Lung Cancer, 55:337-341, 2007

2 . Shiono S, Yoshida J, Nishimura M, Hagiwara M, Hishida T, Nitadori J, Nagai K. Risk factors of postoperative respiratory infections in lung cancer surgery. J Thorac Oncol, 2:34-38, 2007

3 . Nagai K, Sohara Y, Tsuchiya R, Goya T, Miyaoka E; Japan Lung Cancer Registration Committee.
Prognosis of resected non-small cell lung cancer patients with intrapulmonary metastases. J Thorac Oncol, 2:282-286, 2007

4 . Niho S, Fujii H, Murakami K, Nagase S, Yoh K, Goto K, Ohmatsu H, Kubota K, Sekiguchi R, Nawano S, Saijo N, Nishiwaki Y. Detection of unsuspected distant metastases and/or regional nodes by FDG-PET in LD-SCLC scan in apparent limited-disease small-cell lung cancer. Lung Cancer, 57:328-333, 2007

5 . Aokage K, Yoshida J, Nishimura M, Nishiwaki Y, Nagai K. Annual abdominal ultrasonographic examination after curative NSCLC resection. Lung Cancer, 57:334-338, 2007

11 . Pathology Division

1 . Yamauchi C, Hasebe T, Iwasaki M, Imoto S, Wada N, Fukuyama M, Ochiai A. Accurate assessment of lymph vessel tumor emboli in invasive ductal carcinoma of the breast according to tumor areas, and their prognostic significance. Hum Pathol, 38:247-259, 2007

2 . Miyamoto S, Nakamura M, Yano K, Ishii G, Hasebe T, Endoh Y, Sangai T, Maeda H, Shi-Chuang Z, Chiba T, Ochiai A. Matrix metalloproteinase-7 triggers the matricrine action of insulin-like growth factor-II via proteinase activity on insulin-like growth factor binding protein 2 in the extracellular matrix. Cancer Sci, 98:685-691, 2007

3 . Ishii G, Ito TK, Aoyagi K, Fujimoto H, Chiba H, Hasebe T, Fujii S, Nagai K, Sasaki H, Ochiai A. Presence of human circulating progenitor cells for cancer stromal fibroblasts in the blood of lung cancer patients. Stem Cells, 25:1469-1477, 2007

4 . Sano A, Sangai T, Maeda H, Nakamura M, Hasebe T, Ochiai A. Kallikrein 11expressed in human breast cancer cell releases insulin-like growth factor through degradation of IGFBP-3. Int J Oncol, 30:1493-1498, 2007

5 . Naito Y, Ishii G, Kawai O, Hasebe T, Nishiwaki Y, Nagai K, Ochiai A. D2-40-positive solitary fibrous tumors of the pleura: Diagnostic pitfall of biopsy specimen. Pathol Int, 59:618-621, 2007

6 . Aokage K, Ishii G, Nagai K, Kawai O, Naito Y, Hasebe T, Nishimura M, Yoshida J, Ochiai A. Intrapulmonary metastasis in resected pathologic stage IIIB non-small cell lung cancer: possible contribution of aerogenous metastasis to the favorable outcome. J Thorac Cardiovasc Surg, 134:386-391, 2007

7 . Ito TK, Ishii G, Chiba H, Ochiai A. The VEGF angiogenic switch of fibroblasts is regulated by MMP-7 from cancer cells. Oncogene, :, 2007

8 . Tsuruga M, Taki K, Ishii G, Sasaki Y, Furukawa C, Sugihara T, Nomura T, Ochiai A, Magae J. Amelioration of type II diabetes in db/db mice by continuous low-dose-rate gamma irradiation. Radiat Res, 167:592-599, 2007

9 . Yonou H, Ochiai A, Ashimine S, Maeda H, Horiguchi Y, Yoshioka K, Ogawa Y, Hatano T, Tachibana M. The bisphosphonate YM529 inhibits osteoblastic bone tumor proliferation of prostate cancer. Prostate, 67:999-1009, 2007

10 . Sugiura S, Oda T, Aoyagi Y, Matsuo R, Enomoto T, Matsumoto K, Nakamura T, Satake M, Ochiai A, Ohkohchi N, Nakajima M. Microfabricated airflow nozzle for microencapsulation of living cells into 150 micrometer microcapsules. Biomed Microdevices, 9:91-99, 2007

12 . Investigative Treatment Division

1 . Hamaguchi T, Kato K, Yasui H, Morizane C, Ikeda M, Ueno H, Muro K, Yamada Y, Okusaka T, Shirao K, Shimada Y, Nakahama H, Matsumura Y. A phase I and pharmacokinetic study of NK105, a paclitaxel-incorporating micellar nanoparticle formulation. Br J Cancer. , 97:170-176, 2007

2 . Matsumura Y. Preclinical and clinical studies of anticancer drug-incorporated polymeric micelles. J Drug Target, 15:507-517, 2007

13 . Cancer Physiology Project

14 . Cancer Immunotherapy Project

15 . Functional imaging division

1 . Tanaka E, Choi HS, Fujii H, Bawendi MG, Frangioni JV. Image-guided oncologic surgery using invisible light: completed pre-clinical development for sentinel lymph node mapping. Ann Surg Oncol, 13:1671-1681, 2007

2 . Tanaka C, Fujii H, Ikeda T, Jinno H, Nakahara T, Suzuki T, Kitagawa Y, Kitajima M, Ando Y, Kubo A. Stereoscopic scintigraphic imaging of breast cancer sentinel lymph nodes. Breast Cancer, 14:92-99, 2007

3 . Fujii H, Yamagishi H, Ando Y, Tsukamoto N, Kawaguchi O, Kasamatsu T, Kurosaki K, Osada M, Kaneko H, Kubo A. Structuring of free-text diagnostic report. Stud Health Technol Inform, 129:669-673, 2007

16 . Psycho-Oncology Division

1 . Inagaki M, Yoshikawa E, Matsuoka Y, Sugawara Y, Nakano T, Akechi T, Wada N, Imoto S, Murakami K, Uchitomi Y. Smaller regional volumes of brain gray and white matter demonstrated in breast cancer survivors exposed to adjuvant chemotherapy. Cancer, 109:146-156, 2007

2 . Shimizu K, Akechi T, Shimamoto M, Okamura M, Nakano T, Murakami T, Ito T, Oba A, Fujimori M, Akizuki N, Inagaki M, Uchitomi Y. Can psychiatric intervention improve major depression in very near end-of-life cancer patients? Palliat Support Care, 5:3-9, 2007

3 . Miyashita M, Sanjo M, Morita T, Hirai K, Kizawa Y, Shima Y, Shimoyama N, Tsuneto S, Hiraga K, Sato K, Uchitomi Y. Barriers to providing palliative care and priorities for future actions to advance palliative care in Japan: a nationwide expert opinion survey. J Palliat Med, 10:390-399, 2007

4 . Inagaki M, Yoshikawa E, Kobayakawa M, Matsuoka Y, Sugawara Y, Nakano T, Akizuki N, Fujimori M, Akechi T, Kinoshita T, Furuse J, Murakami K, Uchitomi Y. Regional cerebral glucose metabolism in patients with secondary depressive episodes after fatal pancreatic cancer diagnosis. J Affect Disord, 99:231-236, 2007

5 . Morita T, Bito S, Koyama H, Uchitomi Y, Adachi I. Development of a national clinical guideline for artificial hydration therapy for terminally ill patients with cancer. J Palliat Med, 10:770-780, 2007

6 . Miyashita M, Sanjo M, Morita T, Hirai K, Uchitomi Y. Good death in cancer care: a nationwide quantitative study. Ann Oncol, 18:1090-1097, 2007

7 . Asai M, Morita T, Akechi T, Sugawara Y, Fujimori M, Akizuki N, Nakano T, Uchitomi Y. Burnout and psychiatric morbidity among physicians engaged in end-of-life care for cancer patients: a cross-sectional nationwide survey in Japan. Psychooncology, 16:421-428, 2007

8 . Akechi T, Taniguchi K, Suzuki S, Okamura M, Minami H, Okuyama T, Furukawa TA, Uchitomi Y. Multifaceted psychosocial intervention program for breast cancer patients after first recurrence: feasibility study. Psychooncology, 16:517-524, 2007

9 . Fujimori M, Akechi T, Morita T, Inagaki M, Akizuki N, Sakano Y, Uchitomi Y . Preferences of cancer patients regarding the disclosure of bad news. Psychooncology, 16:573-581, 2007

10 . Fujimori M, Parker PA, Akechi T, Sakano Y, Baile WF, Uchitomi Y. Japanese cancer patients' communication style preferences when receiving bad news. Psychooncology, 16:617-625, 2007

11 . Inagaki M, Uchitomi Y, Imoto S. Author reply. Cancer, 110:225, 2007

12 . Nagamine M, Matsuoka Y, Mori E, Fujimori M, Imoto S, Kim Y, Uchitomi Y. Relationship between heart rate and emotional memory in subjects with a past history of post-traumatic stress disorder. Psychiatry Clin Neurosci, 61:441-443, 2007

13 . Tsuchiya M, Iwasaki M, Otani T, Nitadori J, Goto K, Nishiwaki Y, Uchitomi Y, Tsugane S. Breast Cancer in First-degree Relatives and Risk of Lung Cancer: Assessment of the Existence of Gene Sex Interactions. Jpn J Clin Oncol, 37:419-423, 2007

14 . Morita T, Murata H, Hirai K, Tamura K, Kataoka J, Ohnishi H, Akizuki N, Kurihara Y, Akechi T, Uchitomi Y; on Behalf of the Japanese Spiritual Care Task Force. Meaninglessness in terminally ill cancer patients: a validation study and nurse education intervention trial. J Pain Symptom Manage, 34:160-170, 2007

15 . Matsuoka Y, Nagamine M, Mori E, Imoto S, Kim Y, Uchitomi Y. Left hippocampal volume inversely correlates with enhanced emotional memory in healthy middle-aged women. J Neuropsychiatry Clin Neurosci, 19:335-338, 2007

17 . Particle Therapy and Radiation Oncology Division

1 . Kawashima M, Hayashi R, Tahara M, Yamazaki M, Miyazaki M, Arahira S, Ogino T. Accelerated Radiotherapy and Larynx Preservation in Favorable-risk Patients with T2 or Worse Hypopharyngeal Cancer. Jpn J Clin Oncol, 37:345-352, 2007

2 . Nishimura H, Ogino T, Kawashima M, Nihei K, Arahira S, Onozawa M, Katsuta S, Nishio T. Proton-beam therapy for olfactory neuroblastoma. Int J Radiat Oncol Biol Phys, 68:758-762, 2007

3 . Zenda S, Onozawa Y, Boku N, Iida Y, Ebihara M, Onitsuka T. Single-agent Docetaxel in Patients with Platinum-refractory Metastatic or Recurrent Squamous Cell Carcinoma of the Head and Neck (SCCHN). Jpn J Clin Oncol, 37:477-481, 2007



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