Publication list


Clinical Laboratory Division
1. Fujita H, Sasano E, Yasunaga K, Furuta K, Yokota S, Wada I, Himeno M. Evidence for@distinct membrane traffic pathways to melanosomes and lysosomes in melanocytes. J Investig Dermatol Symp Proc 2001;6:19-24.
2. Furuta K, Ikeda M, Nakayama Y, Nakamura K, Tanaka M, Hamasaki N, Himeno M, Hamilton SR, August JT.Expression of lysosome-associated membrane proteins in human colorectal neoplasms and inflammatory diseases.Am J Pathol 2001;159:449-455.
3. Harada M, Sakisaka S, Terada K, Kimura R, Kawaguchi T, Koga H, Kim M, Taniguchi E, Hanada S, Suganuma T,Furuta K, Sugiyama T, Sata M. A mutation of the Wilson disease protein, ATP7B, is degraded in the proteasomes and forms protein aggregates. Gastroenterology 2001;120:967-974.
4. Maekawa M, Sugano K, Ushiama M, Fukayama N, Nomoto K, Kashiwabara H, Fujita S, Kakizoe T. Heterogeneity of DNA methylation status analyzed by Bisulfite-PCR-SSCP and correlation with clinico-pathological characteristics in colorectal cancer. Clin Chem Lab Med 2001;39:121-128.
5. Tsuruta Y, Furuta A, Furuta K, Yamada T, Kira J, Iwaki T. Expression of the lysosome-associated membrane proteins in myopathies with rimmed vacuoles. Acta Neuropathol (Berl) 2001;101:579-584.
6. Goto K, Komada T, Matsuno Y, Yokose T, Asamura H, Kamiya N, Shimosato Y. Clinicopathologic and DNA cytometric analysis of carcinoid tumors of the thymus. Mod Pathol 2001;14:985-994.
7. Hasegawa T, Hirose T, Alberto GA, Ito S, Tomaru U, Matsuno H, Shimoda T, Hirohasi S. Adult neuroblastoma of the retroperitoneum and abdomen clinicopathologic distinction from primitive neuroectodermal tumor. Am J Surg Pathol 2001;25;918-924.
8. Hasegawa T, Matsuno Y, Shimoda T, Umeda T, Yokoyama R, Hirohashi S. Proximal-type epithelioid sarcma: a clinicopathologic study of 20 cases. Mod Pathol 2001;14:665-663.
9. Hasegawa T, Yokoyama R, Matsuno Y, Shimoda T, Hirohashi S. Prognostic significance of histologic grade and nuclear expression of b-catenin in synovial sarcoma. Hum Pathol 2001;32:257-263.
10. Morishita Y, Fukasawa M, Takeuchi M, Inadome Y, Noguchi M. Small-sized. adenocardinoma of lung. Cancer 2001;93:125-131.
11. Moriya Y, Niki T, Yamada T, Matsuno Y, Kondo H, Hirohashi S. Increased expression of laminin-5 its prognostic signification in lung adenocarcinomas of small size. Cancer 2001;91:1129-1141.
12. Okada K, Hasegawa T, Yokoyama R. Rosette-forming epithelioid osteosarcoma: a histologic subtype with a highly aggressive clinical behaviro. Hum Pathol 2001;32:726-733.
13. Saito A, Shimoda T, Nakanishi Y, Ochiai A, Toda G. Histologic heterogeneity and mucin phenotypic expression in early gastric cancer. Pathol Int 2001;51:165-171.
14. Sato H, Hasegawa T, Kanai Y, Tsutsumi Y, Osamura Y, Abe Y, Sakai H, Hirohashi S. Expression of cadherins and their undercoat proteins (a-,b-and g-catenins and p120) and accumulation of b-catenin with no gene mutations in synovial sarcoma. Virchows Arch 2001;438:23-30.
15. Tajima Y, Nakanishi Y, Yoshino T, Kokawa A, Kusano M, Shimoda T. Clinicopathological study of early adenocarcinoma of the gastric cardia:comparison with early adenocarcinoma of the distal stomach and esoahagus. Oncology 2001;61:1-9.
16. Tajima Y, Shimoda T, Nakanishi Y, Yokoyma N, Tanaka T, Shimizu K, Saito T, Kawamura M, Kusano M, Kumagai K. Gastric and intestinal phenotypic marker expression in gastric carcinomas and its prognostic significance: immunohistochemical analysis of 136 lesions. Oncology 2001;61:212-220.
17. Terasaki H, Niki T, Hasegawa T, Yamada T, Suzuki K, Kazumoto M, Fujimoto K Hayaabuchi N, Matsuno Y, Shimoda T. Primary synovial sarcoma of the lung: a case report confirmed by molecular detection of SYT-SSX fusion gene transcrupts. Jpn J Clin Oncol 2001;31:212-216.
18. Tokuno M, Niki T, Eguchi K, Iba S, yamada T, Matsuno Y, Kondou H, Saito Y, Imamura H, Hirohashi S. c-MET sxpression in myofibroblasts. Am J Pathol 2001;158:1451-1463.
19. Yatabe Y, Suzuki R, Matsuno Y, Tobinai K, Ichinohazama R, Tamaru J, Mizoguchi Y, Hashimoto Y, Yamaguchi M, Kojima M, Uike N, Okamoto M, Isoda K, Isomura K, Morishima Y, Seto M, Suchi T, Nakamura S. Morphological spectrum of D1-positive mantle cell lymphoma:study of 168 cases. Pathol Int 2001;51:747-761.
20. Nomoto K, Maekawa M, Sugano K, Ushiama M, Fukayama N, Fujita S, Kakizoe T. Methylation status and expression of human telomerase reverse transcriptase mRNA In relation to hypermethylation of the p16 gene In colorectal cancers as analyzed by Bisulfite-PCR-SSCP. Jpn J Clin Oncol (in press)
21. Ohnishi M, Kanda Y, Takeuchi T, Kim SW, Hori A, Niiya H, Chizuka A, Nakai K, Saito T, Makimoto A, Tanosaki R, Watanabe T, Kobayashi Y, Tobinai K, Takaue Y, Mineishi S. Prophylactic treatment with lamivudine for hepatitis B virus carriers undergoing allogeneic hematopoietic stem cell. Transplantation (in press)
Diagnostic Radiology Division
22. Furukawa H, Iwata R, Moriyama N. Is CT during arterial portography useful for the preoperative evaluation of liver metastases from pancreatic carcinoma? Pancreas 2001;22:200-202.
23. Ohno Y, Adachi S, Motoyama A, Kusumoto M, Hatabu H, Sugimura K, Kono M. Multiphase EKG-triggered 3D contrast-enhanced MR angiography: utility for evaluation of hilar and mediastinal invasion of bronchogenic carcinoma. J Magn Reson Imaging 2001;13:215-224.
24. Okuda K, Takayasu K.Focal nodular hyperplasia. In: Okuda K, Mitchell DG, Itai Y, Ariyama J, editors. Hepatobiliary Diseases. Pathophysiology and Imaging. London: Blackwell Science 2001;457-462.
25. Okuda K, Takayasu K.Primary malignant tumors of the liver. In: Okuda K, Mitchell DG, Itai Y, Ariyama J, editors.Hepatobiliary Diseases. Pathophysiology and Imaging. London: Blackwell Science 2001;343-389.
26. Takayasu K, Muramatsu Y, Maeda T, Iwata R, Furukawa H, Muramatsu Y, Moriyama N, Okusaka T, Okada S, Ueno H. Targeted transarterial oily chemoembolization for small foci of hepatocellular carcinoma using a unified helical CT and angiography system: analysis of factors affecting local recurrence and survival rates. Am J Roentgenol 2001;176:681-688.
27. Takayasu K. Vascular anatomy of the liver and vascular anomalies. In: Okuda K, Mitchell DG, Itai Y, Ariyama J, editprs. Hepatobiliary Diseases. Pathophysiology and Imaging. London: Blackwell Science 2001;215-227.
28. Tomiyama N, Mueller NL, Ellis SJ, Cleverley JR, Okumura M, Miyoshi S, Kusumoto M, Johkoh T, Yosida S,Mihara N, Honda O, Kozuka T, Hamada S, Nakamura H. Invasive and noninvasive thymoma: distinctive CT features. J Comp Assist Tomogr 2001;25:388-393.
29. Uchiyama N, Miyakawa K, Moriyama N, Kumasaki T. Radiographic features of invasive lobular carcinoma of the breast. Radiati Med 2001;19:19-25.
Endoscopy Division
30. Fu K.-I, Fuji T, Kato S, Sano Y, Koba I, Mera K, Saito H, Yoshino T, Sugito M, Yoshida S. A new endoscopic tattooing technique for identifying the location of colonic lesions during laparoscopic surgery: a comparison with the conventional technique. Endoscopy 2001;33:687-691.
31. Fujii T, Hasegawa RD, Saitoh Y, Fleischer D, Saito Y, Sano Y, Kato S. Chromoscopy during colonoscopy.Endoscopy 2001; 33:1036-1104.
32. Gotoda T, Sasako M, Ono H, Katai H, Sano T, Shimoda T. Evaluation of the necessity for gastrectomy with lymph node dissection for patients with submucosal invasive gastric cancer. Br J Surg 2001;88:444-449.
33. Kobayashi T. Transbronchial approaches for the diagnosis and treatment of small peripheral pulmonary lesions. In:Yoshimura H, Kida A, Arai T, Niimi S, Kaneko M, Kitahara S, editors. Bronchology and Bronchoesophagology:State of the Art. Amsterdam: Elsevier 2001;147-158.
34. Kondo H, Fukuda H, Ono H, Gotoda T, Saito D, Takahiro K, Shirao K, Yamaguchi H, Yoshida S. Sodium thiosulfate solution spray for relief of irritation caused by Lugolis stain in chromoendoscopy. Gastrointest Endosc 2001;53:199-202.
35. Ono H, Kondo H, Gotoda T, Shirao K, Yamaguchi H, Saito D, Hosokawa K, Shimoda T, Yoshida S. Endoscopic mucosal resection for treatment of early gastric cancer. Gut 2001;48:225-229.
36. Rembacken B, Fujii T, Kondo H. The recognition and endoscopic treatment of early gastric and colonic cancer.Bailliers Best Pract Res Clin Gastroenterol 2001;15:317-336.
37. Rembacken BJ, Gotoda T, Fuji T, Axon ATR. Endoscopic mucosal resection. Endoscopy 2001;33:709-718.
38. Saito Y, Fujii T, Akasu T, Gotoda T, Kozu T, Saito D, Sano Y. Development of an aggressive depressed cancer in a case of familial adenomatous polyposis. Endoscopy (in press)
39. Saito Y, Fujii T, Kondo H, Mukai H, Yokota T, Kozu T, Saito D. Endoscopic treatment for laterally spreading tumors in the colon. Endoscopy 2001;33:682-686.
40. Blaser MJ, Saito D. Trends in reported adenocarcinomas of the esophagus and gastric cardia in Japan. Eur J Gastroenterol Hepatol (in press)
41. Sobue T, Moriyama N, Kusumoto M, Kaneko M, Kobayashi T, Tsuchiya R, Kakinuma R, Ohmatsu H, Nagai K,Nishiyama H, Matsui E, Eguchi K. Screening for lung caner with low-dose helical computed tomography. J Clin Oncol (in press)
Breast and Medical Oncology Division
42. Ando M, Watanabe T, Nagata , Narabayashi M, Adachi I., Katsumata N. Efficacy of docetaxel 60mg/m2 in patients with metastatic breast cancer according to the status of anthracycline resistance. J Clin Oncol 2001;19:336-342.
43. Minami H, Sasaki Y, Watanabe T, Ogawa M. Pharmacodynamic modeling of entire time course of leukopenia after a 3-hour infusion of paclitaxel. Jpn J Cancer Res 2001;92:231-238.
Gastrointestinal Oncology Division
44. Matsumura Y. DDS in cancer chemotherapy. In : Chiellini E. editor. Biomedical Polymers and Polymer Therapeutics Publisher. New York: Kluwer Academic/Plenum Publishers 2001;37-52.
45. Mizumura Y, Matsumura Y, Hamaguchi T, Nishiyama N, Kataoka K, Kawaguchi T, Hrushesky WJM, Moriyasu F,Kakizoe T. Cisplatin-incorporated polymeric micelles eliminate nephrotoxicity, while maintaining antitumor activity. Jpn J Cancer Res 2001;92:328-336.
46. Nakanishi T, Fukushima S, Okamoto K, Suzuki M, Matsumura Y, Yokoyama M, Okano T, Sakurai Y, Kataoka K.Development of the polymer micelle carrier system for doxorubicin. J Control Release 2001;74:295-302.
47. Tsukioka Y, Matsumura Y, Hamaguchi T, Goto M, Muro K, Yamada Y, Shirao K. Complete response achieved following administration of S-1 in a patient with adrenal gland metastasis of 5-FU-resistant gastric cancer: a case report. Jpn J Clin Oncol 2001;31:450-453.
48. Tsukuda H, Matsumura Y, Inoue I, Kobayashi Y, Ookawa K, Aoki T, Nebiki H, Yamazaki O, Kondo H, Kakizoe T. Diagnostic application of CD44 variant expression in pancreatic juice for detection of pancreatic neoplasm.Anticancer Res 2001;2:2175-2184.
49. Yamada Y, Shirao K, Ohtsu A, Boku N, Hyodo I, Saitoh H, Miyata Y, Taguchi T. Phase II trial of paclitaxel by three-hour infusion for advanced gastric cancer with short premedication for prophylaxis against paclitaxel-associated hypersensitivity reactions. Ann Oncol 2001;12:1133-1137.
50. Yamao T, Shirao K, Matsumura Y, Muro K, Yamada Y, Goto M, Chin K, Shimada Y. Phase I/II study of irinotecan combined with mitomycin-C in patients with advanced gastric cancer. Ann Oncol 2001;12:1729-1735.
51. Namiki Y, Muro K, Shirao K, Shimada Y, Matsumura Y, Yamada Y, Gotoh T, Hamaguchi T, Mizuno T, Ura T. Prognostic factors for patients with metastatic colorectal cancer receiving protracted venous infusion of 5FU. Am J Clin Oncol (In press)
52. Sumiyoshi T, Gotoda T, Muro K, Goto M, Sumiyoshi Y, Ono H, Saito D. Placement of self-expandle metalic stents for patients with advanced esophageal cancer after chemoradiotherapy or radiotherapy -Is it safe?-. Gastrointest Endosc (in press)
Hematology Division
53. Igarashi T, Ohtsu T, Fujii H, Morishima Y, Ogura M, Kagami Y, Kinoshita T, Kiyama Y, Tobinai K. Re-treatment of relapsed indolent B-cell lymphoma with rituximab. Int J Hematol 2001;73:213-221.
54. Kobayashi Y, Nakata M, Maekawa M, Takahashi M, Fujii H, Matsuno Y, Fujishiro M, Ono H, Saito D, Takenaka T,Hirase N, Nishimura J, Akioka T, Enomoto K, Mikuni C, Hishima T, Fukayama M, Sugano K, Hosoda F, Ohki M,Tobinai K. Detection of t(11;18) MALT-type lymphoma with dual-color fluorescence in situ hybridization and reverse transcriptase-polymerase chain reaction analysis. Diagn Mol Pathol 2001;10:207-213.
55. Saito T, Togitani K, Murakami J, Watanabe T, Tanosaki R, Kobayashi Y, Matsuno Y, Tobinai K.Granular lymphocytic leukemia derived from gd T-cell expressing cytotoxic molecules. Leukemia Res 2001;25:259-261.
56. Tobinai K. Clinical trials of a mouse-human chimeric anti-CD20 monoclonal antibody (rituximab) for B-cell lymphoma in Japan. Cancer Chemother Pharmacol 2001;48:S85-S90.
57. Yamada Y, Tomonaga M, Fukuda H, Hanada S, Utsunomiya A, Tara M, Sano M, Ikeda S, Takatsuki K, Kozuru M, Araki K, Kawano F, Niimi M, Tobinai K, Hotta T, Shimoyama M and members of the JCOG-Lymphoma Study Group (1994-1996). A new G-CSF-supported combination chemotherapy, LSG15, for adult T-cell leukemia-lymphoma:Japan Clinical Oncology Group Study 9303. Br J Haematol 2001;113:375-382.
58. Igarashi T, Kobayashi Y, Ogura M, Kinoshita T, Ohtsu T, Sasaki Y, Morishima Y, Murate T, Kasai M, Uike N,Taniwaki M, Kano Y, Ohnishi K, Matsuno Y, Nakamura S, Mori S, Ohashi Y, Tobinai K and Members of the IDEC-C2B8 Study Group in Japan. Factors affecting toxicity, response and progression-free survival in relapsed patients with indolent B-cell lymphoma and mantle cell lymphoma treated with rituximab: Japanese phase II study. Ann Oncol (in press)
59. Murakami J, Fukushima N, Ueno H, Saito T, Watanabe T, Tanosaki R, Kobayashi Y, Matsuno Y, Tobinai K. Primary hepatic low-grade marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue type: a case report and review of the literature. Int J Hematol (in press)
60. Murayama T, Imoto S, Gomyo H, Mizuno I, Kajimoto K, Sugimoto T, Tobinai K, Koizumi T. Successful cytoreduction with CAG (cytarabine, aclarubicin and G-CSF) therapy in refractory acute myelogenous leukemia before allogeneic bone marrow transplantation. Hematology (in press)
Hematopoietic Stem Cell Transplantation Team
61. Asada-Mikami R, Heike Y, Kanai S, Azuma M, Shirakawa K, Takaue T, Krasnykh V, Curiel DT, Terada M, Abe T,Wakasugi H. Efficient gene transfection by RGD-fiber modified recombinant adenoviruse to dendritic cells. Jpn J Cancer Res 2001;92:321-327.
62. Kanda Y, Mineishi S, Nakai K, Tanosaki R, Takaue Y. Frequent detection of rising cytomegalovirus antigenemiaafter allogeneic stem cell transplantation following a regimen containing anti-thymocyte globulin. Blood 2001;97:3676-3677.
63. Kanda Y, Mineishi S, Saito T, Seo S, Saito A, Ohnishi M, Suenaga K, Niiya H, Nakai K, Takeuchi T, Kawahigashi Y, Shoji N, Ogasawara T, Tanosaki R, Kobayashi Y, Tobinai K, Kami M, Mori S, Suzuki R, Kunitoh H, Takaue Y.Pre-emptive therapy against cytomegalovirus (CMV) diseases guided by CMV antigenemia assay after allogeneic hematopoietic stem cell transplantation: a single-center experience in Japan. Bone Marrow Transplant 2001;27:437-444.
64. Kato K, Takaue Y, Wakasugi H. T cell conditioned medium efficiently induces the maturation and function of human dendritic cells. J Leukoc Biol 2001;70:941-949.
65. Matsubara H, Makimoto A, Takayama J, Higa T, Saito T, Tanosaki R, Mineishi S, Ohira M, Takaue Y. Suggested clinical benefits of the use of peripheral blood stem cells over bone marrow in allogeneic transplantation settings for the treatment of childhood leukemia. Jpn J Clin Oncol 2001;31:30-34.
66. Mineishi S, Saito T, Kanda Y, Tanosaki R, Tobinai K, Takaue Y. Delayed recovery of neutrophil counts after peripheral stem cell transplantation which improved with minimal dose of G-CSF administration. Jpn J Clin Oncol 2001;31:43-45.
67. Niiya H, Kanda Y, Saito T, Ohnishi T, Kanai S, Kawano Y, Kamijo K, Iizuka A, Yakushijin K, Ueda K, Chizuka A, Iijima K, Ohnishi M, Nakai K, Makimoto A, Tanosaki R, Tobinai K, Wakasugi H, Takaue Y, Mineishi S. Early full donor myeloid chimaerism after reduced-intensity stem cell transplantation using a combination of fludarabine and busulfan. Haematologica 2001;86:1071-1074.
68. Saito T, Nakamura F, Kanda Y, Tanosaki R, Takaue Y, Mineishi S. Possible place of non-myeloablative regimen in second transplantation with a mismatched related donor for relapsing and refractory leukemia after initial unrelated donor transplantation. Haematologica 2001;86:780-781.
69. Saito T, Seo S, Kanda Y, Shoji N, Ogasawara T, Murakami J, Tanosaki R, Tobinai K, Takaue Y, Mineishi S. Early onset Pneumocystis carinii pneumonia after allogeneic peripheral blood stem cell transplantation. Am J Hematol 2001;67:206-209.
70. Suenaga K, Kanda Y, Niiya H, Nakai K, Saito T, Saito A, Ohnishi M, Takeuchi T, Tanosaki R, Makimoto A,Miyawaki S, Ohnishi T, Kanai S, Takaue Y, Mineishi S. Successful application of non-myeloablative transplantation for paroxysmal nocturnal hemoglobinuria. Exp Hematol 2001;29:639-642.
71. Hamaki T, Katori H, Kami M, Yamato T, Yamakado H, Kusumi E, Itoh T, Miyakoshi S, Igarashi M, Kanda Y,Mineishi S, Mukai M, Hayashi M, Takaue Y, Hara S, Mutou Y. Successful allogeneic blood stem cell transplantation for aplastic anemia in a patient with renal insufficiency requiring dialysis. Bone Marrow Transplant (in press)
72. Kami M, Machida U, Okuzumi K, Matsumura T, Mori S, Hori A, Kashima T, Kanda Y, Takaue Y, Sakamaki H,Hirai H, Yoneyama A, Mutou Y. Effect of fluconazole prophylaxis on fungal blood cultures: an autopsy-based study involving 720 patients with hematological malignancy. Br J Haematol (in press)
73. Kanda Y, Mineishi S, Saito T, Saito A, Ohnishi M, Niiya H, Chizuka A, Nakai K, Takeuchi T, Matsubara H,Makimoto A, Tanosaki R, Kunitoh H, Tobinai K, Takaue Y. Response-oriented pre-emptive therapy against cytomegalovirus disease with low-dose ganciclovir: a prospective evaluation. Transplantation (in press)
74. Kanda Y, Mineishi S, Saito T, Saito A, Yamada S, Ohnishi M, Chizuka A, Niiya H, Suenaga K, Nakai K, Takeuchi T, Makimoto A, Tanosaki R, Kami M, Tanaka Y, Fujita S, Watanabe T, Kobayashi Y, Tobinai K, Takaue Y. Long-term low-dose acyclovir against varicella-zoster virus reactivation after allogeneic hematopoietic stem cell transplantation. Bone Marrow Transplant (in press)
75. Nakai K, Kanda Y, Mineishi S, Saito T, Ohnishi M, Niiya H, Chizuka A, Takeuchi T, Matsubara H, Kami M,Makimoto A, Tanosaki R, Kunitoh H, Tobinai K, Takaue Y. Suggested delayed immune recovery against cytomegalovirus after allogeneic blood stem cell transplantation with a reduced-intensity regimen. Bone Marrow Transplant (in press)
76. Ohnishi M, Kanda Y, Takeuchi T, Kim SW, Hori A, Niiya H, Chizuka A, Nakai K, Saito T, Makimoto A, Tanosaki R, Watanabe T, Kobayashi Y, Tobinai K, Takaue Y, Mineishi S. Limited efficacy of lamivudine against hepatitis B virus infection in allogeneic hematopoietic stem cell transplant recipients. Transplantation (in press)
77. Saito T, Kanda Y, Kami M, Shoji N, Kato K, Shoji N, Kanai S, Ohnishi T, Kawano Y, Nakai K, Ogasawara T,Matsubara H, Makimoto A, Tanosaki R, Tobinai K, Wakasugi H, Takaue Y, Mineishi S. Therapeutic potential of a reduced-intensity preparative regimen for allogeneic transplantation with cladribine, busulfan and anti-thymocyte globulin against advanced/refractory acute leukemia/lymphoma. Clin Cancer Res (in press)
78. Shimokawa T, Ohashi H, Takaue Y, Kawano Y, Abe T, Kuroda Y. Successful umbilical cord blood transplantation in an infant with ALL who failed initial autologous peripheral blood stem cell transplantation. Med Pediatr Oncol (in press)
79. Watanabe T, Mineishi S, Kawano Y, Takaue Y. Partially matched transplants with allogeneic CD34+ blood cells. Leuk Lymphoma (in press)
80. Watanabe T, Takaue Y, Kawano Y, Koike K, Kikuta A, Imaizumi M, Watanabe A, Eguchi H, Ohta S, Horikoshi Y,Iwai A, Makimoto A, Kuroda Y. HLA-identical sibling peripheral blood stem cell transplantation in children and adolescents. Biol Blood Marrow Transplant (in press)
Hepatobiliary and Pancreatic Oncology Division
81. Ikeda M, Okada S, Tokuuye K, Ueno H, Okusaka T. Prognostic factors in patients with locally advanced pancreatic cancer receiving chemoradiotherapy. Cancer 2001;91:490-495.
82. Ikeda M, Okada S, Ueno H, Okusaka T, Kuriyama H. Radiofrequency ablation and percutaneous ethanol injection in patients with small hepatocellular carcinoma: a comparative study. Jpn J Clin Oncol 2001;31:322-326.
83. Ikeda M, Okada S, Ueno H, Okusaka T, Kuriyama H. Spontaneous regression of hepatocellular carcinoma with multiple lung metastases: a case report. Jpn J Clin Oncol 2001;31:454-458.
84. Mashige F, Tsuno NH, Kaekawa M, Okada S, Tanaka N, Matsui M, Watanabe S, Nakahara K. Noninvasive combination assay of free L-fucose and sulfated bile acids in urine for diagnosis of liver and pancreatic diseases and solid tumor. Journal of Analytical Bio-Science 2001;24:317-323.
85. Okada S, Sato T, Yamamoto S. djuvant interferon for hepatocellular carcinoma. Hepatology 2001;33:481-482.
86. Okada S, Ueno H, Okusaka T, Ikeda M, Furuse J, Maru Y. Phase I trial of gemcitabine in patients with advanced pancreatic cancer. Jpn J Clin Oncol 2001;31:7-12.
87. Okada S. Cancer chemoprevention as adjuvant therapy for hepatocellular carcinoma. Jpn J Clin Oncol 2001;31:357-358.
88. Okusaka T, Okada S, Ueno H, Ikeda M, Shimada K, Yamamoto J, Kosuge T, Yamasaki S, Fukushima N, Sakamoto M. Abdominal pain in patients with resectable pancreatic cancer with reference to clinicopathological findings.Pancreas 2001;22:279-284.
89. Okusaka T,Okada S, Tokuuye K, Wakasugi H, Saisho H, Ishikawa O, Matsuno S, Sato T, Sato K for the Non-surgical Treatment Group for Pancreatic Cancer in Japan Lack of effectiveness of radiotherapy combined with cisplatin for locally advanced pancreatic cancer. Cancer 2001;91:1384-1389.
90. Ueno H, Okada S, Okusaka T, Ikeda M, Tanaka N, Sakamoto M, Yoshimori M. Prognosis of hepato-cellular carcinoma with no tumor stain treated by percutaneous ethanol injection. Hepatogastroenterology 2001;48:1430-1434.
91. Ikeda M, Okada S, Tokuuye K, Ueno H, Okusaka T. A phase I trial of weekly gemcitabine and concurrent radiotherapy in patients with locally advanced pancreatic cancer. Br J Cancer (in press)
92. Okada S, Okuda K. Management of hepatocellular carcinoma: current practice and future options. Int J Gastroenterol (in press)
93. Okusaka T, Okada S, Ueno H, Ikeda M, Iwata R, Furukawa H, Takayasu K, Moriyama N, Sato T, Sato K.Transcatheter arterial embolization with zinostatin stimalamer (SMANCS) for hepatocellular carcinoma. Oncology(in press)
94. Ueno H, Okada S, Okusaka T, Ikeda M, Kuriyama H. Phase I and pharmaco-kinetic study of 5-fluorouracil administered by 5-day continuous infusion in patients with hepatocellular carcinoma. Cancer Chemother Pharmacol (in press)
95. Ueno H, Okada S, Okusaka T, Ikeda M, Kuriyama H. Phase II study of uraciltegafur (UFT) in patients with metastatic pancreatic cancer. Oncology (in press)
Pain Medicine and Palliative Care Division
96. Collins J, Shimoyama N, Bruera E, Takeda F, Kakizoe T, Sugimura T. Report of the 14th International Symposium of the Foundation for Promotion of Cancer Research: pain control, palliative medicine and psycho-oncology. Jpn J Clin Oncol 2001;31:459-468.
97. Shimoyama M, Shimoyama N. Antinociceptive and respiratory effects of intrathecal DALDA and DALDA analog.J Pharmacol Exp Ther 2001;297:364-371.
98. Shimoyama N, Shimoyama M. Nebulized furosemide as a novel treatment for dyspnea in terminal cancer patients. J Pain Symptom Manage (in press)
Pediatric Oncology Division
99. Kounami S, Douno S, Matsubara H, Takayama J, Ohira M. Olfactory neuroblastoma as a second malignant neoplasm in a patient previously treated for childhood acute leukemia. Pediatr Hematol Oncol 2001;18:459-463.
100. Ohnuma K, Isoyama K, Ikuta K, Toyoda Y, Nakamura J, Nakajima F, Tsuchida M, Ohira M, Suminoe A, Hara T,Nishihira H. Cord blood transplantation from HLA-mismatched unrelated donors as a treatment for children with haematological malignancies. Br J Haematol 2001;112:981-987.
Psycho-Oncology Division
101. Akechi T, Nakano T, Okamura H, Ueda S, Akizuki N, Nakanishi T, Yoshikawa E, Matsuki H, Hirabayashi E,Uchitomi Y. Psychiatric disorders in cancer patients: descriptive analysis of 1721 psychiatric referrals at two Japanese cancer center hospitals. Jpn J Clinl Oncol 2001;31:188-194.
102. Akechi T, Okamura H, Nishiwaki Y, Uchitomi Y. Psychiatric disorders and associated and predictive factors in patients with unresectable non-small cell lung carcinoma. A longitudinal study. Cancer 2001;92:2609-2622.
103. Akechi T, Okamura H, Yamawaki S, Uchitomi Y. Why do some cancer patients with depression desire an early death and others do not? Psychosomatics 2001;42:141-145.
104. Akechi T, Okuyama T, Imoto S, Yamawaki S, Uchitomi Y. Biomedical and psychosocial determinants of psychiatric morbidity among postoperative ambulatory breast cancer patients. Breast Cancer Res Treat 2001;65:195-202.
105. Murakami Y, Gondo N, Okamura H, Akechi T, Uchitomi Y. Guilt from negative genetic test findings. Am J Psychiatry 2001;158:1929.
106. Okano Y, Okamura H, Watanabe T, Narabayashi M, Katsumata N, Ando M, Adachi I, Kazuma K, Akechi T,Uchitomi Y. Mental adjustment to first recurrence and correlated factors in patients with breast cacner. Breast Cancer Res Treat 2001;67:255-262.
107. Okuyama T, Tanaka K, Akechi T, Okamura H, Nishiwaki Y, Hosaka T, Uchitomi Y. Fatigue in ambularoty patients with lung cancer -prevalence, correlated factors, and screening-. J Pain Symptom Manage 2001;22:554-564.
108. Uchitomi Y, Kugaya A, Akechi T, Nakano T, Wenner M, Okamura H, Takebayashi M, Kagaya A, Saeki T,Yamawaki S. Three sets of diagnostic criteria for major depression and correlations with serotonin-induced platelet calcium mobilization in cancer patients. Psychopharmacology (Berl) 2001;153:244-248.
109. Uchitomi Y, Mikami I, Nakano T, Okuyama T, Akechi T, Okamura H. Physician support and patientsi psychologic responses after surgery for nonsmall cell lung caarcinoma: a prospective observational study. Cancer 2001;92:1926-1935.
110. Akechi T, Nakano T, Akizuki N, Nakanishi T, Yoshikawa E, Okamura H, Uchitomi Y. Psychiatric evaluation of competency in cancer patients. International Journal of Psychiatry in Clinical Practice (in press)
111. Akizuki N, Okamura H, Akechi T, Nakano T, Yoshikawa E, Nakanishi T, Uchitomi Y. Clinical experience of the pharmacological treatment algorithm for major depression in advanced cancer patients: preliminary study. International Journal of Psychiatry in Clinical Practice (in press)
112. Morita T, Akechi T, Sugawara Y, Chihara S, Uchitomi Y. Practices and attitudes of Japanese oncologists and palliative care physicians concerning Aeterminal sedationAf: a nationwide survey. J Clin Oncol (in press)
113. Sugawara Y, Akechi T, Shima Y, Okuyama T, Akizuki N, Nakano T, Uchitomi Y. Efficacy of methylphenidate for fatigue in advanced cancer patients-a preliminary study. Palliat Med (in press)
Thoracic Oncology Division
114. Akiyama Y, Ohe Y, Tamura T, Sawada M, Inoue A, Kusaba H, Yamamoto N, Sekine I, Kunitoh H, Kodama T, SaijoN. A dose escalation study of paclitaxel and carboplatin in untreated Japanese patients with advanced non-small cell lung cancer. Jpn J Clin Oncol 2001;31:482-487.
115. Fujisaka Y, Saijo N. Case of a patient with small-cell lung cancer treated with irinotecan plus cisplatin. Case Studies in Oncology 2001;3:2-7.
116. Fukuoka K, Arioka H, Iwamoto Y, Fukumoto H, Kurokawa H, Ishida T, Tomonari A, Suzuki T, Usuda J, Kanzawa F,Saijo N, Nishio K. Mechanism of the radiosensitization induced by vinorelbine in human non-small cell lung cancer cells. Lung Cancer 2001;34:451-460.
117. Fukuoka K, Usuda J, Iwamoto Y, Fukumoto H, Nakamura T, Yoneda T, Narita N, Saijo N, Nishio K. Mechanisms of action of the novel sulfonamide anticancer agent E7070 on cell cycle progression in human non-small cell lung cancer cells. Invest New Drugs 2001;19:219-227.
118. Heike Y, Kasono K, Kunisaki C, Hama S, Saijo N, Tsuruo T, Kuntz DA., Rose DR, Curiel DT. Overcoming multi-drug resistance using an intracellular anti-MDR1 sFv. Int J Cancer 2001;92:115-122.
119. Inoue A, Kunitoh H, Sekine I, Sumi M, Tokuuye K, Saijo N. Radiation pneumonitis in lung cancer patients: a retrospective study of risk factors and the long-term prognosis. Int J Radiat Oncol Biol Phys 2001;49:649-655.
120. Inoue A, Saijo N. Recent advances in the chemotherapy of non-small cell lung cancer. Jpn J Clin Oncol 2001;31:299-304.
121. Kanzawa F, Koizumi F, Koh Y, Nakamura T, Tatsumi Y, Fukumoto H, Saijo N, Yoshioka T, Nishio K. In vitro synergistic interactions between the cisplatin analogue nedaplatin and the DNA topoisomerase I inhibitor irinotecan and the mechanism of this interaction. Clin Cancer Res 2001;7:202-209.
122. Kawahara M, Kris MG, Green M, Kunitoh H. New drug and multimodality combinations in the treatment of advanced non-small cell lung cancer. Semin Oncol 2001;28:1-4.
123. Kunitoh H, Akiyama Y, Kusaba H, Yamamoto N, Sekine I, Ohe Y, Kubota K, Tamura T, Shinkai T, Kodama T, Goto K, Niho S, Nishiwaki Y, Saijo N. A phase I/II trial of cisplatin, docetaxel and ifosfamide in advanced or recurrent non-small cell lung cancer. Lung Cancer 2001;33:259-265.
124. Kurata T, Tamura T, Shinkai T, Ohe Y, Kunitoh H, Kodama T, Kakinuma R, Matsumoto T, Kubota K, Omatsu H,Nishiwaki Y, Saijo N. Phase I and pharmacological study of paclitaxel given over 3 h with cisplatin for advanced non-small cell lung cancer. Jpn J Clin Oncol 2001;31:93-99.
125. Nakamura T, Koizumi F, Kaneko N, Tamura T, Chiwaki F, Koh Y, Akutagawa S, Saijo N, Nishio K. Reversal of cisplatin resistance by the 1,4-benzothiazepine derivative, JTV-519. Jpn J Cancer Res 2001;92:597-602.
126. Natsume T, Nakamura T, Koh Y, Kobayashi M, Saijo N, Nishio K. Gene expression profiling of exposure to TZT-1027,a novel microtubule-interfering agent,in non-small cell lung cancer PC-14 cells and astrocytes. Invest New Drugs 2001;19:293-301.
127. Nishio K, Nakamura T, Koh Y, Kanzawa F, Tamura T, Saijo N. Oncoprotein 18 overexpression increases the sensitivity to vindesine in the human lung carcinoma cells. Cancer 2001;91:1494-1499.
128. Noda K, Nishiwaki Y, Kawahara M, Negoro S, Sugiura T, Yokoyama A, Fukuoka M, Mori K, Watanabe K, Tamura T, Yamamoto S, Saijo N. Irinotecan plus cisplatin compared with etoposide plus cisplatin for extensive small-cell lung cancer. N Engl J Med 2002;346:85-91.
129. Ohe Y, Niho S, Kakinuma R, Kubota K, Matsumoto T, Ohmatsu H, Goto K, Kunitoh H, Saijo N, Nishiwaki Y. Phase I studies of cisplatin and docetaxel administered by three consecutive weekly infusions for advanced non-small cell lung cancer in elderly and non-elderly patients. Jpn J Clin Oncol 2001;31:100-106.
130. Ohe Y, Saijo N. Topoisomerase I targeting agents in small-cell lung cancer. Curr Oncol Rep 2001;3:170-178.
131. Saijo N, Tamura T, Yamamoto N, Nishio K. New strategies for cancer therapy in 21st century. Cancer Chemother Pharmacol 2001;(Suppl 1):S102-106.
132. Sekine I, Saijo N. Growth-stimulating pathways in lung cancer: Implications for targets of therapy. Clinical Lung Cancer 2001;2:299-306.
133. Shimizu M, Tamura T, Yamada Y, Akiyama Y, Saijo N, Nishio K. CPT-11 alters the circadian rhythm of dihydropyrimidine dehydrogenase mRNA in mouse liver. Jpn J Cancer Res 2001;92:554-561.
134. Tatsumi Y, Arioka H, Ikeda S, Fukumoto H, Miyamoto K, Fukuoka K, Ohe Y, Saijo N, Nishio K. Enhancement of in vivo antitumor activity of a novel antimitotic 1-phenylpropenone derivative, AM-132, by tumor necrosis factor-a or interleukin-6. Jpn J Cancer Res 2001;92:768-777.
135. Tsuchiya S, Ohe Y, Sugiura T, Fuwa N, Kitamoto Y, Mori K, Kobayashi H, Nakata K, Sawa T, Hirai K, Etoh T, Saka H, Saito A, Fukuda H., Ishizuka, N, Saijo, N. Randomized phase I study of standard-fractionated or accelerated-hyperfractionated radiotherapy with concurrent cisplatin and vindesine for unresectable non-small cell lung cancer:a report of Japan Clinical Oncology Group Study (JCOG 9601). Jpn J Clin Oncol 2001;31:488-494.
136. Tsunoda T, Nakamura T, Ishimoto K, Yamaue H, Tanimura H, Saijo N, Nishio K. Upregulated expression of angiogenesis genes and down regulation of cell cycle genes in human colorectal cancer tissue determined by cDNA macroarray. Anticancer Res 2001;21:137-144.
137. Usuda J, Okunaka T, Furukawa K, Tsuchida T, Kuroiwa Y, Ohe Y, Saijo N, Nishio K, Konaka C, Kato H. Increased cytotoxic effects of photodynamic therapy in IL-6 gene transfected cells via enhanced apoptosis. Int J Cancer 2001;93:475-480.
138. Yoshida M, Feng W, Nishio K, Takahashi M, Heike Y, Saijo N, Wakasugi H, Ikekawa T. Antitumor action of the PKC activator gnidimacrin through CDK2 inhibition. Int J Cancer 2001;94:348-352.
139. Kanzawa F, Akiyama Y, Saijo N, Nishio K. In vitro effects of combinations of cis-amminedichloro (2-methylpyridine)platinum (II) (ZD0473) with other novel anticancer drugs on the growth of SBC-3, a human small cell lung cancer cell line. Lung Cancer (in press)
140. Koh Y, Nishio K, Saijo N. Mechanisms of action of cancer chemotherapeutic agents: topoisomerase inhibitors. In: Cancer Handbook, Chapter 86. London: Reference Nature Publishing Group (in press)
141. Koh Y, Tsunoda T, Iwahashi M, Yamaue H, Ishimoto K, Tanimura H, Fukumoto H, Nakamura T, Tatsumi Y,Shimizu M, Saijo N, Nishio K. Decreased expression of a2,8 sialy transferase and increased expression of b1,4 N-acetylgalactosaminyl transferase in gastrointestinal cancers. Exp Biol Med (in press)
142. Naruse I, Ohmori T, Ao Y, Fukumoto H, Kuroki T, Mori M, Saijo N, Nishio K. Antitumor activity of the selective epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) Iressatm (ZD1839) in a EGFR-expressing multidrug resistant cell line in vitro and in vivo. Int J Cancer (in press)
143. Natsume T, Koh Y, Kobayashi M, Fukumoto H, Takahashi F, Nakamura T, Ohe Y, Saijo N, Nishio K. Enhanced antitumor activities of TZT-1027 against TNF-a or IL-6 secreting Lewis lung carcinoma in vivo. Cancer Chemother Pharmacol (in press)
144. Takahashi F, Akutagawa S, Fukumoto H, Tsukiyama S, Ohe Y, Takahashi K, Fukuchi Y, Saijo N, Nishio K.Osteopontin induces angiogenesis of murine neuroblastoma cells in mice. Int J Cancer (in press)
Radiation Oncology Division
145. Ando K, Furusawa Y, Suzuki M, Nojima K, Majima H, Koike S, Aoki M, Shimizu W, Futami Y, Ogino T,Murayama S, Ikeda H. Relative biological effectiveness of the 235 MeV proton beams at the National Cancer Center Hospital East. Jpn J Radiat Res 2001;42:79-89.
146. Goto K, Kodama T, Sekine I, Kakinuma R, Kubota K, Hojo F, Matsumoto T, Ohmatsu H, Ikeda H, Ando M,Nishiwaki Y. Serum levels of KL-6 are useful biomarkers for severe biomarkers for severe radiation pneumonitis.Lung Cancer 2001;34:141-148.
147. Ikeda H. Editorial: Structure of Radiotherapy in Japan. Jpn J Clin Oncol 2001;31:133-134.
148. Ito Y, Kamijo T, Yokose T, Kawashima M, Ogino T, Ikeda H, Hayashi R, Sasaki S, Ochiai A. Microvessel density predicts the radiosensitivity of metastatic head and neck squamous cell carcinoma in cervical lymph nodes. Int J Oncol 2001;19:1127-1132.
149. Japan Lymphoma Radiation Therapy Group: Shikama N, Ikeda H, Nakamura S, Oguchi M, Isobe K, Hirota S,Hasegawa M, Nakamura K, Sasai K, Hayabuchi N. Localized aggressive non-HodgkinAfs lymphoma of the nasal cavity: a survey by the Japan Lymphoma Radiation Therapy Group. Int J Radiat Oncol Biol Phys 2001;51:1228-1233.
150. Kawashima M, Ogino T, Hayashi R, Ishikura S, Nihei K, Ito Y, Ikeda H, Ebihara S, Itai Y. Influence of postsurgical residual tumor volume on local control in radiotherapy for maxillary sinus cancer. Jpn J Clin Oncol 2001;31:195-202.
Breast Surgery Division
151. Akashi-Tanaka S, Fukutomi T, Miyakawa K, Nanasawa T, Matsuo K, Hasegawa T, Tsuda H. Contrast-enhanced computed tomography diagnosing the intraductal component and small invasive foci of breast cancer. Breast Cancer2001;8:10-15.
152. Akashi-Tanaka S, Fukutomi T, Watanabe T, Katsumata N, Nanasawa T, Matsuo K, Miyakawa K, Tsuda H. Accuracy of contrast-enhanced computed tomography in the prediction of residual breast cancer after neoadjuvant chemotherapy. Int J Cancer (Radiat Oncol Invest) 2001;96:66-73.
153. Fukutomi T, Akashi-Tanaka S, Nanasawa T, Matsuo K, Shimizu C. Multicentricity and histopathological features of familial breast cancers stratified by menopausal status. Int J Clin Oncol 2001;6:80-83.
154. Fukutomi T, Akashi-Tanaka S. Differeces in the progesterone receptor contents between familial breast cancers and sporadic breast cancers stratified by patient age. Surg Today 2001;31:963-967.
155. Iwamoto E, Fukutomi T, Akashi-Tanaka S. Validation and problems of St-Gallen recommendations of adjuvant therapy for node-negative invasive breast cancer in Japanese patients. Jpn J Clin Oncol 2001;31:259-262.
156. Kubo M, Fukutomi T, Akashi-Tanaka S, Hasegawa T. Association of breast cancer with meningioma: report of a case and review of the literature. Jpn J Clin Oncol 2001;31:510-513.
157. Matsuo K, Fukutomi T, Tsuda H, Hasegawa T, Akashi-Tanaka S, Nanasawa T. A case of malignant phyllodes with osteosarcomatous feature of the breast. Breast Cancer 2001;8:79-83.
158. Takahashi T, Akashi-Tanaka S, Fukutomi T, Watanabe T, Katsumata N, Miyakawa K, Hasegawa T, Tsuda H. Two special types of breast cancer presenting as progressive disease after neoadjuvant chemotherapy with docetaxel plus doxorubicin. Breast Cancer 2001;8:234-237.
159. Takarabe T, Tsuda H, Okada S, Fukutomi T, Hirohashi S. Detection of numerical alterations of chromosome 1 in cytopathological specimens of breast tumors by chromogen in situ hybridization. Pathol Int 2001;51:786-791.
160. Tsuda H, Takarabe T, Akashi-Tanaka S, Fukutomi T, Hirohashi S. Pattern of chromosome 16q loss differs between an atypical proliferative lesion and ductal carcinoma which occurred metachronously in the same area of the breast.Mod Pathol 2001;14:382-388.
161. Yajima S, Fukutomi T, Akashi-Tanaka S, Nanasawa T, Miyakawa K, Hasegawa T. Diabetic mastopathy: a case report with reference to the findings of enhanced computed tomography. Breast Cancer 2001;8:246-249.
162. Akashi-Tanaka S, Fukutomi T. Role of computed tomography on selection of the treatment of breast cancer. Breast Cancer (in press)
163. Fukutomi T. Prognostic and predictive factors in adjuvant setting. Breast Cancer (in press)
164. Ichizawa N, Fukutomi T. Long-term results of T1a, T1b and T1c breast carcinomas in Japanese Women: Validation of the UICC T1 subgroup classification. Jpn J Clin Oncol (in press)
165. Matsuo K, Fukutomi T. Concordance in pathological response to neoadjuvant chemotherapy between invasive and noninvasive components of primary breast carcinomas. Breast Cancer (in press)
166. Matsuo K, Fukutomi T. Differences in estrogen receptor status, HER2, and p53 comparing metachronous bilateral breast carcinoma. J Surg Oncol (in press)
167. Matsuo K, Fukutomi T. Histological and immunohistochemical analysis of apocrine breast carcinoma. Breast Cancer (in press)
168. Matsuo K, Fukutomi T. Histological grade, p53, HER2 and hormone receptor status of synchronous bilateral breast carcinoma. Breast Cancer (in press)
Colorectal Surgery Division
169. Fujita S. Kudo N. Akasu T. Moriya Y. Detection of cytokeratin 19 and 20 m RNA in peripheral anda mesenteric blood from colorectal cancer patients anda their prognosis. Int J Colorectal Dis 2001;16:141-146.
170. Kawamura Jr. A, Sekine T, Sekiguchi M, Yanoma A, Kaneko A. Haneda T, Moriya Y. Hayasaka K, Kakizoe T. Six-year disease-free survival of a patient with metastatic eyelid cell carcinoma and colon adenocarcinoma after repeated postoperative adoptive immunotherapy. Jpn J Clin Oncol 2001;30:267-271.
171. Mass CP, Moriya Y, Steup WH, Kranenbarg KE, van de Velde CJH. A prospective study on radical and nerve-preserving surgery for rectal cancer in the Netherlands. Eur J Surg Oncol 2001;26:751-757.
172. Matsuoka N. Moriya Y. Akasu T. Fujita S. Long-term outcome of urinary function after extended lymphadenectomy in patients with distal rectal cancer. Eur J Surg Oncol 2001;27:165-169.
Dermatology Division
173. Ishihara K, Saida T, Yamamoto A. Update statisical data of malignant melanoma in Japan. Int J Clin Oncol 2001;6:109-116.
174. Ishikawa M, Nakanishi Y, Yamazaki N, Yamamoto A. Malignant eccrine spiradenoma: a case report and review of the literature. Dermatol Surg 2001;27:67-70.
175. Kiniwa Y, Fujita T, Akada M, Ito K, Shufuda T, Suzuki Y, Yamamoto A,Saida T, Kawakami Y. Tumor antigens isolated from a patient with vitiligo and T-cell-infiltrated melanoma. Cancer Res 2001;61:7900-7907.
176. Wakamatsu K, Kageshita M, Furue M, Hatta N, Kiyohara Y, Nakayama J,Ono T, Saida T, Takata M, Tsuchida T,Uhara A, Yamamoto A, Yamazaki N, Naito A, Ito S. Evaluation of 5-S-cysteinyldopa as a marker of melanoma progression: 10 yearsi experience. Melanoma Res (in press)
Esophageal Surgery Division
177. Fang W, Igaki H, Tachimori Y, Sato H, Daiko H, Kato H. Three-field lymph node dissection for esophageal cancer in elderly patients over 70 years of age. Ann Thorac Surg 2001;72:867-871.
178. Fang W, Kato H, Chen W, Tachimori Y, Igaki H, Sato H. Comparison of surgical management of thoracic esophageal carcinoma between two referral centers in Japan and China. Jpn J Clin Oncol 2001;31:203-208.
179. Ide H, Kobayashi A, Yamana H, Udagawa H, Ozawa S, Tachimori Y, Saito T, Tanaka O, Matsubara H, Kato H,Barron JP, Isono K. Comprehensive registry of esophageal cancer in Japan from 1988 to 1994. In: Pinotti HW,Cecconello I, Felix VN, de Oliveira MA, editors. Recent Advances in Diseases of the Esophagus. San Pauro:Monduzzi Editore 2001;373-378.
180. Igaki H, Kato H, Tachimori Y, Daiko H, Fukaya M, Yajima S, Nakanishi Y. Clinicopathologic characteristics andsurvival of patients with clinical Stage I squamous cell carcinomas of the thoracic esophagus treated with three-field lymph node dissection. Eur J Cardiothorac Surg. 2001;20:1089-1094.
181. Igaki H, Kato H, Tachimori Y, Sato H, Daiko H, Nakanishi Y. Prognostic evaluation for squamous cell carcinomas of the lower thoracic esophagus treated with three-field lymph node dissection. Eur J Cardiothorac Surg.2001;19:887-893.
182. Kokawa A, Yamaguchi H, Tachimori Y, Kato H, Watanabe H, Nakanishi Y. Other primary cancers occurring after treatment of superficial oesophageal cancer. Br J Surg. 2001;88:439-443.
183. Kubota K, Kato H, Tachimori Y, Watanabe H, Yamaguchi H, Nakanishi Y, Iinuma G. Surgical therapy for recurrent esophageal cancers at anastomoses after esophagectomy. Hepatogastroenterology 2001;48:1364-1367.
Gastric Surgery Division
184. Bonenkamp JJ, Sasako M, Hermans J, van de Velde CJH. Tumor load and surgical palliation in gastric cancer.Hepatogastroenterol 2001;48:1219-1221.
185. Davis P, Sano T. The difference in gastric cancer between Japan, USA and Europe: What are the facts? What are the suggestions? Crit Rev Oncol Hematol 2001;40:77-94.
186. Fukagawa T, Sasako M, Mann GB, Sano T, Katai H, Maruyama K, Nakanishi Y, Shimoda T.Immunohistochemically detected micrometastases of the lymph nodes in patients with gastric carcinoma. Cancer2001;92:753-760.
187. Sano T, Sasako M. Green tea and gastric cancer. (Editorial) N Engl J Med 2001;344:675-676.
188. Sano T. Is peritoneal carcinomatosis an incurable disease or controllable locoregional condition? - Challenge of surgeons with intraperitoneal hyperthermic chemotherapy. (Editorial) Jpn J Clin Oncol 2001;31:571-572.
189. van Krieken CHJM, Sasako M, van de Velde CJH. Chapter 17: Gastric Cancer. In: Gospodarowicz MK, Henson DE, Hutter RVP, OiSullivan B, Sobin LH, Wittekind CH editors. Prognostic Factors in Cancer (2nd Ed). New York:Wiley-Liss. 2001;251-265.
190. Yamaguchi T, Sano T, Katai H, Sasako M, Maruyama K. Node-positive mucosal gastric cancer: a follow-up study.Jpn J Clin Oncol 2001;31:153-156.
191. Sano T, Katai H, Sasako M, Maruyama K. One thousand consecutive gastrectomies without operative mortality. Br J Surg (in press)
Gynecology Division
192. Kasamatsu T, Hasegawa T, Tsuda S, Okada S, Sawada M, Yamada T, Tsunematsu R, Ohmi K, Mizuguchi T, Kawana T. Primary epithelioid sarcoma of the vulva. Int J Gynecol Cancer 2001;11:316-320.
Hepatobiliary and Pancreatic Surgery Divison
193. Okabayashi T, Yamamoto J, Kosuge T, Shimada K, Yamasaki S, Takayama T, Makuuchi M. A new staging system for mass-forming intrahepatic cholangiocarcinoma: analysis of preoperative and postoperative variables. Cancer2001;92:2374-2383.
194. Sugawara Y, Yamamoto J, Yamasaki S, Shimada K, Kosuge T, Makuuchi M. Estimating the prognosis of hepatic resection in patients with metastatic liver tumors from colorectal cancer with special concern for the timing of hepatectomy. Surgery 2001;129:408-413.
195. Takigawa Y, Sugawara Y, Yamamoto J, Shimada K, Yamasaki S, Kosuge T, Makuuchi M. New lesions detected by intraoperative ultrasound during liver resection for hepatocellular carcinoma. Ultrasound Med Biol 2001;27:151-156.
196. Yamamoto J, Okada S, Shimada K, Okusaka T, Yamasaki S, Ueno H, Kosuge T. Treatment strategy for small hepatocellular carcinoma: comparison of long-term results after percutaneous ethanol injection therapy and surgical resection. Hepatology 2001;34:707-713.
Neurosurgery Division
197. Nomura K. Epidemiology of germ cell tumors in Asia of pineal region tumor. J Neurooncol 2001;54:211-217.
198. Tanaka M, Shibui S, Nomura S, Nakanishi Y. Radiotherapy combined with hydrochloride and etoposide for malignant gliomas:Results of a pilot study. Jpn J Clin Oncol 2001;31:246-250.
Ophthalmology Division
199. Inomata M, Kaneko A, Kunimoto T, Saijo N. In vitro thermo- and thermochemo-sensitivity of retinoblastoma cells from surgical specimens. Int J Hyperthermia (in press)
Orthopedic Division
200. Kimura K, Shinmura K, Hasegawa T, Beppu Y, Yokoyama R, Yokota J. Germline p53 mutation in a patient with multiple primary cancers. Jpn J Clin Oncol 2001;31:349-351.
Thoracic Surgery Division
201. Asamura H. Boundary between N1 and N2 stations in lung cancer: back to the future of anatomy: reply. Ann Thorac Surg 2001;72:1440.
202. Asamura H. Complete resection: Yes or no? J Thorac Cardiovasc Surg 2000;119:193-194.
203. Carbone E, Asamura H, Takei H, Kondo H, Suzuki K, Miyaoka E, Tsuchiya R, Motta G. T2 tumors larger than five centimeters in diameter can be upgraded to T3 in non-small cell lung cancer. J Thorac Cardiovasc Surg 2001;122:907-912.
204. Ichinose Y, Tsuchiya R, Koike T, Kuwahara O, Nakagawa K, Yamamoto Y, Kobayashi K, Watanabe Y, Kase M,Yokoi K. Prognosis of resected non-small cell lung cancer patients with carcinomatous pleuritis of minimal disease.Lung Cancer 2001;32:55-60.
205. Ichinose Y, Tsuchiya R, Yasumitsu T, Koike T, Yamamoto Y, Nakagawa K, Tada H, Yokoi K, Nagai K, Kase M.Prognosis of non-small cell lung cancer patients with positive pleural lavege cytology after a thoracotomy: results of the survey conducted by the Japan Clinical Oncology Group. Lung Cancer 2001;31:17-41.
206. Naruke T, Kondo H, Tsuchiya R, Asamura H. Prognosis and survival after resection for bronchogenic carcinoma based on the 1997 TNM-staging classification: the Japanese experience. Ann Thorac Surg 2001;71:439-442.
207. Okumura T, Asamura H, Suzuki K, Kondo H, Tsuchiya R. Intrapulmonary metastasis of non-small cell lung cancer:a prognostic assessment. J Thorac Cardiovasc Surg 2001;122:24-28.
208. Okumura T, Kondo H, Suzuki K, Asamura H, Kobayashi T, Kaneko M, Tsuchiya R. Fluoroscopy-assisted thoracoscopic surgery after computed tomography-guided bronchoscopic barium marking. Ann Thorac Surg2001;71:439-442.
209. Sagawa M, Koike T, Sato M, Oda M, Kondo T, Kato H, Tsuchiya R. Segmentectomy for roentgenographically occult bronchogenic squamous cell carcinoma. Ann Thorac Surg 2001;71:1439-1442.
210. Takagi K, Tsuchiya R, Watanabe Y. Surgical approach to pleural diffuse mesothelioma in Japan. Lung Cancer 2001;31:57-65.
211. Asamura H, Suzuki K, Kondo H, Tsuchiya R. Mechanical vascular division in lung resection. Eur J Cardio-thorac Surg (in press)
212. Takei H, Asamura H, Suzuki K, Kondo H, Tsuchiya R. Large cell neuroendocrine carcinoma of the lung. J Thorac Cardiovasc Surg (in press)
Urology Division
213. Shigyo M, Sugano K, Tobisu K, Tsukamoto T, Sekiya T, Kakizoe T. Molecular followup of newly diagnosed bladder cancer using urine samples. J Urol 2001;166:1280-1285.
214. Stenzl A, Jarolim L, Coloby P, Golia S, Bartsch G, Babjuk M, Kakizoe T, Robertson C. Urethra-sparing cystectomy and orthotopic urinary diversion in women with malignant pelvic tumors. Cancer 2001;92:1864-1871.
215. Yamaguchi N, Kakizoe T. Synergistic interaction between helicobacter pylori gastritis and diet in gastric cancer. The Lancet Oncology 2001;2:88-94.
216. Yoshimura K, Arai Y, Fujimoto H, Nishiyama H, Ogura K, Okino T, Ogawa O. Prognostic impact of extensive parenchymal invasion pattern in pT3 renal pelvic transitional cell carcinoma. Cancer (in press)
ASCO 2001 ABSTRACTS
1. Makimoto A, Mineishi S, Tanosaki R, Kanda Y, Saito T, Nakai K, Matsubara H, Ohira M, Fujimoto H, Tobisu K,Yamamoto A, Takaue Y, Kakizoe T. Nonmyeloablative stem-cell transplantation (NST) for refractory solid tumors.ASCO 2001, Abstract No.44.
2. Kanda Y, Saito T, Nakai K, Ohnishi M, Ohnishi T, Makimoto A, Tanosaki R, Tobinai K, Takaue Y, Mineishi S.Cladribine/busulfan/anti-thymocyte globulin combination for non-myeloablative transplantation enables rapid complete donor chimerism with suggested anti-tumor activity against hematological malignancies. ASCO 2001,Abstract No.71.
3. Tokuda Y, Tajima T, Narabayashi M, Takeyama K, Watanabe T, Fukutomi T, Chou T, Sano M, Igarashi T, Sasaki Y,Ogura M, Murai H, Okamoto S, Ogita M, Kasai M, Kobayashi T, Ishizuka N, Takashima S, Shimoyama M, Tobinai K. Randomized phase III study of high-dose chemotherapy with autologous stem cell support as consolidation in high-risk postoperative breast cancer: Japan Clinical Oncology Group (JCOG9208). ASCO 2001, Abstract No.148.
4. Ikuo S, Yamamoto N, Kunitoh H, Ohe Y, Tamura T, Kodama T, Saijo N. Relationship between objective responses in phase I trials and activity of investigational new drugs. ASCO 2001, Abstract No.308.
5. Yamada Y, Shirao K, Matsumura Y, Muro K, Goto M, Hamaguchi T, Mizumura Y, Tsukioka Y, Hayashi S, Morizane C, Murakami H, Fujisaka Y, Nagayama S. Comparison of 5-fluorouracil and F-E?-alanin pharmacokinetics in patients receiving protracted venous infusion of 5-fluorouracil and oral S-1. ASCO 2001, Abstract No.362.
6. Ohtsu A, Boku N, Nagashima F, Koizumi W, Tanabe S, Saigenji K, Muro K, Matsumura Y, Shirao K. A phasae I/II study of S-1plus cisplatin (CDDP) in patients (pts) with advanced gastric cancer (AGC). ASCO 2001, Abstract No.656.
7. Kuriyama H, Okada S, Okusaka T, Ueno H, Ikeda M. Prognostic factors in patients with hepatocellular carcinoma treated by percutaneous ethanol injection. ASCO 2001, Abstract No.673.
8. Goto K, Nishiwaki Y, Yokoyama A, Mori K, Watanabe K, Saijo N. Serum levels of KL-6 are useful biomarkers for severe radiation pneumonitis. ASCO 2001, Abstract No.1113.
9. Itoh K, Ohtsu T, Sasaki Y, Ogura M, Morishima Y, Chou T, Yoshida K, Uike N, Niimi M, Fukuda H, Hotta T,Shimoyama M, Tobinai K. Randomized phase II study of biweekly CHOP and dose-escalated CHOP with prophylactic use of lenograstim (glycosylated G-CSF) in aggressive non-Hodgkinis lymphoma: Japan Clinical Oncology Group Study 9505. ASCO 2001, Abstract No.1153.
10. Kato H, Konaka C, Tsuboi M, Genka K, Takizawa T, Sakuma A, Saijo N, Ohta M. A randomized phase III study comparing ubenimex (BestatinR) versus placebo as postoperative adjuvant treatment in patients with stage I squamous cell lung cancer. ASCO 2001, Abstract No.1225.
11. Kunitoh H, Watanabe K, Ohashi Y, Niitani H. Preliminary results of a randomized phase III trial of docetaxel (D)and cisplatin (P) versus vindesine (V) and P in stage IV non small cell lung cancer (NSCLC). ASCO 2001, Abstract No.1289.
12. Negoro S, Nakagawa K, Fukuoka M, Kudoh S, Tamura T, Yoshimura N, Takeda K, Tanigawara Y, Swaisland H.Final results of a phase I intermittent dose-escalation trial of ZD1839(eIressai) in Japanese patients with various solid tumours. ASCO 2001, Abstract No.1292.
13. Ohe Y, Ishizuka N, Tamura T, Sekine I, Nishiwaki Y, Saijo N. Long-term follow -up results of unresectable locally advanced non-small cell lung cancer (NSCLC) treated with chemoradiotherapy (CRT). ASCO 2001, AbstractNo.1319.
14. Yoshida K, Sugiura T, Takifuji S, Kawahara M, Matsui K, Kudoh S, Fukuoka M, Takada M, Ariyoshi Y, Ishizuka N,Saijo N. Randomized phase II trial of three intrapleural therapy regimens in non-small cell lung cancer (NSCLC)with malignant pleural effusion (MPE): Japan Clinical Oncology Group Study (JCOG9515). ASCO 2001, Abstract No.1351.
15. Kubota K, Nishiwaki Y, Sugiura T, Noda K, Kawahara M, Mori K, Tamura T, Nakamura S, Yokoyama A, Watanabe K, Negoro S, Saijo N. A pilot study of cisplatin and etoposide plus concurrent accelerated hyperfractionated thoracic radiotherapy (TRT) followed by three cycles of irinotecan and cisplatin for the treatment of limited-stage small-cell lung cancer (SCLC): JCOG 9903-DI. ASCO 2001, Abstract No.1378.
16. Higa T, Makimoto A, Matsubara H, Horie K, Murayama S, Ohira M, Kaneko A. Successful preservation of eye ball by application of multidisciplinary local ophthalmic treatments (LOT) for unilateral retinoblastoma. ASCO 2001,Abstract No.1493.
17. Matsuo K, Fukutomi T, Watanabe T, Hasagawa T, Katsumata N, Tsuda T, Akashi S. Evalution of pathological response to neoadjuvant chemotherapy in locally advanced breast cancer. ASCO 2001, Abstract No.1776.
18. Akashi-Tanaka S, Watanabe T, Fukutomi T, Katsumata N, Miyakawa K, Hasegawa T, Tsuda H. Diagnosis of residual breast cancer after neoadjuvant AT chemotherapy using contrast-enhanced computed tomography. ASCO 2001, Abstract No.1829.
19. Shirao K, Matsumura Y, Yamada Y, Muro K, Goto M, Boku N, Ohtsu A, Sano Y, Mutoh M, Nagashima F,Tanigawara Y. Tolerability and pharmacokinetic profile of Oxaliplatin in Japanese solid tumor patients. ASCO 2001,Abstract No.2124.
20. Igarashi T, Sasaki Y, Ogura M, Morishima Y, Kinoshita T, Kano Y, Kasai M, Ohnishi K, Uike N, Taniwaki M,Kobayashi Y, Tobinai K. Pre-treatment variables affecting serum rituximab levels in relapsed patients with indolent B-cell non-Hodgkinis lymphoma. ASCO 2001, Abstract No.2154.
21. Ueno H, Okada S, Okusaka T, Ikeda M, Kuriyama H, Tokuuye K, Sumi M, Kagami Y, Murayama S, Ikeda H. Phase I trial of hyperfractionated radiation therapy (HFRT) with protracted 5-fluorouracil (5-FU) infusion in patients with locally advanced pancreatic cancer (PC). ASCO 2001, Abstract No.2266.
22. Muro K, Shirao K, Shimada Y, Yamao T, Ikeda N, Hyodo I, Saito H, Iwase H, Tsuji Y, Ohtsu A, Tamura T, Yamamoto S. A phase II study of sequential methotrexate and 5-fuluorouracil for advanced gastric cancer with malignant ascites: JCOG9603. ASCO 2001, Abstract No.2277.
23. Tanimoto E, Shirao K, Hamaguchi T, Goth M, Muro K, Yamada Y, Matsumura Y. 5-Fluorouracil/Methotrexate sequential chemotherapy for gastric cancer with paritoneal metastasis. ASCO 2001, Abstract No.2279.
24. Tobinai K, Kobayashi Y, Morishima Y, Ogura M, Uike N, Chou T, Sugai S, Kasai M, Miura I, Murayama T.Prolonged cytopenia and myelodysplastic syndrome after cladribine treatment in relapsed patients with indolent non-Hodgkinis lymphoma: Results of Japanese phase II study. ASCO 2001, Abstract No.2664.
25. Ogura M, Takenaka T, Kagami Y, Itoh K, Sasaki Y, Kinoshita T, Tobinai K, Okamoto M, Hirano M, Fukuda H,Hotta T, Shimoyama M. Phase II study of ABVd therapy for advanced stage Hodgkinis disease in Japan: Japan Clinical Oncology Group Study (JCOG9305). ASCO 2001, Abstract No.2673.

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