2. Ochiai A, Yamauchi Y, Hirohashi S. p53 mutations in the non-neoplastic mucosa of the human stomach showing intestinal metaplasia. Int J Cancer, 69:28-33, 1996
3. Cho J-H, Noguchi M, Ochiai A, Hirohashi S. Loss of heterozygosity of multiple tumor suppressor genes in human gastric cancers by polymerase chain reaction. Lab Invest, 74:835-841, 1996
4. Baffa R, Negrini M, Mandes B, Rugge M, Ranzani GN, Hirohashi S, Croce CM. Loss of heterozygosity for chromosome 11 in adenocarcinoma of the stomach. Cancer Res, 56:268-272, 1996
5. Uchino S, Hirohashi S. Molecular events in gastric cancer. Asian J Surgery, 19:207-217, 1996
6. Ohsawa N, Sakamoto M, Saito T, Kobayashi M, Hirohashi S. Numerical chromosome aberrations in hepatocellular carcinoma detected by fluorescence in situ hybridization. J Hepatol, 25:655-662, 1996
7. Tsuda H, Sakamaki C, Shimamura K, Hirohashi S. Detection of allele loss on chromosome 16q in DNA isolated from fine needle aspiration specimens of breast tumors: a simulation study using surgically resected specimens. Acta Cytol, 40:625-630, 1996
8. Kanai Y, Ushijima S, Tsuda H, Sakamoto M, Sugimura T, Hirohashi S. Aberrant DNA methylation on chromosome 16 is an early event in hepatocarcinogenesis. Jpn J Cancer Res, 87:1210-1217, 1996
9. Narimatsu H, Iwasaki H, Nishihara S, Kimura H, Kudo T, Yamauchi Y, Hirohashi S. Genetic evidence for the Lewis enzyme, which synthesizes type-1 Lewis antigens in colon tissue, and intracellular localization of the enzyme. Cancer Res, 56:330-338, 1996
10. Hui A-M, Sakamoto M, Kanai Y, Ino Y, Gotoh M, Yokota J, Hirohashi S. Inactivation of p16INK4 in hepatocellular carcinoma. Hepatology, 24:575-579, 1996
11. Nishibori H, Matsuno Y, Iwaya K, Osada T, Kubomura N, Iwamatsu A, Kohno H, Sato S, Kitajima M, Hirohashi S. Human colorectal carcinomas specifically accumulate Mr 42,000 ubiquitin-conjugated cytokeratin 8 fragments. Cancer Res, 56:2752-2757, 1996
12. Muta H, Noguchi M, Kanai Y, Ochiai A, Nawata H, Hirohashi S. E-cadherin gene mutations in signet ring cell carcinoma of the stomach. Jpn J Cancer Res, 87:843-848, 1996
13. Shibata T, Ochiai A, Kanai Y, Akimoto S, Gotoh M, Yasui N, Machinami R, Hirohashi S. Dominant negative inhibition of the association between beta-catenin and c-erbB-2 by N-terminally deleted beta-catenin suppresses the invasion and metastasis of cancer cells. Oncogene, 13:883-889, 1996
14. Sakamoto M, Ino Y, Ochiai A, Kanai Y, Akimoto S, Hirohashi S. Formation of focal adhesion and spreading of polarized human colon cancer cells in association with tyrosine phosphorylation of paxillin in response to phorbol ester. Lab Invest, 74:199-208, 1996
15. Inomata M, Ochiai A, Akimoto S, Kitano S, Hirohashi S. Alteration of beta-catenin expression in colonic epithelial cells of familial adenomatous polyposis patients. Cancer Res, 56:2213-2217, 1996
16. Shibata T, Ochiai A, Gotoh M, Machinami R, Hirohashi S. Simultaneous expression of cadherin-11 in signet-ring cell carcinoma and stromal cells of diffuse-type gastric cancer. Cancer Lett, 99:147-153, 1996
17. Ono M, Sakamoto M, Ino Y, Moriya Y, Sugihara K, Muto T, Hirohashi S. Cancer cell morphology at the invasive front and expression of cell adhesion-related carbohydrate in the primary lesion of patients with colorectal carcinoma with liver metastasis. Cancer, 78:1179-1186, 1996
18. Yamada T, Endo R, Tsukagoshi K, Fujita S, Honda K, Kinoshita M, Hasebe T, Hirohashi S. Aberrant expression of a hemidesmosomal protein, bullous pemphigoid antigen 2, in human squamous cell carcinoma. Lab Invest, 75:589-600, 1996
19. Osada T, Sakamoto M, Ino Y, Iwamatsu A, Matsuno Y, Muto T, Hirohashi S. E-cadherin is involved in the intrahepatic metastasis of hepatocellular carcinoma. Hepatology, 24:1460-1467, 1996
20. Noguchi M, Hirohashi S. Cell lines from non-neoplastic liver and hepatocellular carcinoma tissue from a single patient. In Vitro Cell Dev Biol, 32:135-137, 1996
21. Emura M, Ochiai A, Hirohashi S. In vitro reconstituted tissue as an alternative to human respiratory tract. Toxicol Lett, 88:81-84, 1996
22. Kawasaki M, Noguchi M, Morikawa A, Matsuno Y, Yamada T, Hirohashi S, Kondo H, Shimosato Y. Nuclear p53 accumulation by small-sized adenocarcinomas of the lung. Pathol Int, 46:486-490, 1996
23. Sano T, Yamamoto J, Kosuge T, Inoue K, Shimada K, Takayama T, Yamazaki S, Sakamoto M, Hirohashi S. Intrahepatic cholangiocarcinoma presenting intrabile duct tumor growth: report of a case. Hepatogastroenterology, 43:667-670, 1996
24. Ishii H, Okada S, Nose H, Okusaka T, Yoshimori M, Takayama T, Kosuge T, Yamasaki S, Sakamoto M, Hirohashi S. Local recurrence of hepatocellular carcinoma after percutaneous ethanol injection. Cancer, 77:1792-1796, 1996
25. Okusaka T, Okada S, Nose H, Ishii H, Nakasuka H, Nakayama H, Nagahama H, Yoshimori M, Shimada K, Yamamoto J, Takayama T, Kosuge T, Yamasaki S, Sakamoto M, Hirohashi S. The prognosis of patients with hepatocellular carcinoma of multicentric origin. Hepatogastroenterology, 43:919-925, 1996
26. Okada S, Ishii H, Nose H, Okusaka T, Kyogoku A, Yoshimori M, Shimada K, Yamamoto J, Kosuge T, Yamasaki S, Sakamoto M, Hirohashi S. Effect of heavy alcohol intake on long-term results after curative resection of hepatitis C virus-related hepatocellular carcinoma. Jpn J Cancer Res, 87:867-873, 1996
27. Ochiai T, Yamamoto J, Kosuge T, Shimada K, Takayama T, Yamasaki S, Ozaki H, Nakanishi Y, Mukai K. Adenosquamous carcinoma with different morphologic and histologic components arising from the intrahepatic bile duct: report of a case. Hepatogastroenterology, 43:663-666, 1996
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