List of Seminars Held in 1997


JAN 17
Jerrold M. Ward (Chief, Veterinary and Tumor Pathology Section, Office of Laboratory Animal Science, National Cancer Institute, USA)
Gene function and Knockout mice: genes associated with carcinogenesis
Organized by Chemotherapy Division
22
Robert L. Cohen (Associate Director, Molecular Oncology Department,Genetech Inc,USA)
Development of a humanized antibody against HER2 for the treatment of solid tumor
Organized by Pharmacology Division
30
Yasuhiro Kishi (Assistant Professor, Department of Neuropsychiatry, Nippon Medical School, Japan)
Depression and suicide in the medically ill
Organized by Psycho-Oncology Division

FEB 10
Tsuneyuki Ubagai (Visiting Postdoctoral Fellow, National Institute of Child Health and Human Development, National Institutes of Health, USA)
Molecular mechanisms of an inborn error of the methionine pathway:
methionine adenosyltransferase deficiency

Organized by Carcinogenesis Division

 28
Fred K. Gey (Professor, Department of Biochemistry & Molecular Biology, University of Berne, Switzerland)
Is concurrent adequacy of antioxidant vitamins and other micronutrients a prerequisite for preventing early stage of cardiovascular disease and cancer respectively?
Organized by Epidemiology and Biostatistics Division

MAR 10
Nicholas H. Heintz (Associate Professor, Department of Microbiology and Molecular Genetics, University of Vermont, USA)
Regulation of dhfr gene expression by E2F during the cell cycle
Organized by Biology Division

 21
Anne-Marie Schmitt-Verhulst (Director, Research INSERM, Group Leader at CIML, Parc Scientifique et Technologique de Luminy Centre dユimmunologie de Marseille Luminy CNRS INSERM, France)
Lineage selection in the thymus and T cell activation programs in the periphery
Organized by Studies on Host-immune Response

 25
Susumu Imaoka (Lecturer, Osaka City University Medical School, Japan)
CYP4Bl: Its inplication in bladder carcinogenesis
Organized by Investigative Treatment Division

APR 2
Andrew R. Marks (Professor, Medicine and Pharmacology, Director, Molecular Cardiology Program College of Physicians & Surgeons, Columbia University, USA)
Role of IP3-induced calcium release in the regulation of apoptosis
Organized by Director's Office

 3
Francesco Ramirez (Professor, Molecular Biology, The Mount Sinai School of Medicine, USA)
Creating a mouse model for Marfan syndrome and learning about the problems of gene targeting
Organized by Director's Office

 10
Robert I. Garver Jr. (Associate Professor, Department of Medicine, Pulmonary and Critical Care Medicine, The University of Alabama, USA)
Amplification strategies for gene therapy of solid tumors
Organized by Pharmacology Division

 24
Hyo-Jeong Kuh (Research Associate, Ohio State University, USA)
Target site pharmacokinetics of paclitaxel: implication on in vitro and in vivo pharmacokinetics
Organized by Pharmacology Division

MAY 1
Wannee R. Kusamran (Head, Biochemistry and Chemical Carcinogenesis Section, Research Division, National Cancer Institute, Thailand)
Antimutagenic and anticarcinogenic potential of Thai vegetables
Organized by Cancer Prevention Division

 13
Anna A. DePaoli-Roach (Professor, Department of Biochemistry and Molecular Biology, Indiana University School of Medicine)
Mechanisms of regulation of serine/threonine protein phosphatases
Organized by Carcinogenesis Division

 19
Curtis C. Harris (Chief, Laboratory of Human Carcinogenesis, National Cancer Institute, National Institutes of Health, USA)
Modulation of the cell cycle and apoptosis by tumor suppressor genes
Organized by Biology Division

 22
Karl-Friedrich Becker (Head, Laboratory for Molecular Pathology, Technical University Munich, Germany)
E-cadherin gene mutations in human tumors: functional analysis and clinical implications
Organized by Pathology Division

 26
Leonard Hayflick (Professor, University of California, San Francisco School of Medicine, USA)
The cell biology of longevity determination: is there a telomere clock?
Organized by Cancer Prevention Division

JUN 26
Makito Emura (Professor, Experimental Oncology, Institute of Experimental Pathology, Hannover Medical School, Germany)
Application of in vivo and in vitro lung epithelial cell differentiation system for the study of carcinogen metabolism
Organized by Pathology Division

 27
George J. Martine (Vice President, World Wide Clinical Research, Rhone-Poulenc Rorer Gencell, USA)
Gene therapy for solid tumor
Organized by Pharmacology Division

JUL 11
Eric R. Fearon (Professor, Division of Molecular Medicine and Genetics, University of Michigan Medical Center, USA)
DCC: Is there a link between tumorigenesis and cell guidance mechanisms?
Organized by Biology Division

 18
Hiroshi Yamasaki (Chief, Unit of Multistage Carcinogenesis, International Agency for Research on Cancer Lyon, France)
Connexins and growth control
Organized by Pathology Division

 22
Rashmi Sinha (Investigator, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA)
Well done red meat, heterocyclic amines and human cancer
Organized by Cancer Prevention Division

 23
Kunio Yagi (Director, Institute of Applied Biochemistry, Japan)
Cationic liposome
Organized by Carcinogenesis Division

 24
Naoto Shimoyama (Assistant Professor, Pain Clinic, Department of Anesthesiology, School of Medicine, Chiba University, Japan)
Current state of American palliative therapy
Organized by Psycho-Oncology Division

Youichi Nabeshima (Chief, National Institute of Neuroscience, National Cancer of Neurology and Psychiatry, Japan)
For elucidation of mechanisms of aging: phenotypes of a senile mutant mouse and its genetics
Organized by Carcinogenesis Division

 30
Toshihisa Ishikawa (Director, Pfizer Pharmaceutical Co., Japan)
The GSX pump in normal and cancer cells
Organized by Pharmacology Division

AUG 25
Roderick H. Dashwood (Associate Professor, Department of Environmental Biochemistry, University of Hawaii, USA)
Carcinogenicity and chemoprevention studies with heterocyclic amine colon carcinogenesis
Organized by Carcinogenesis Division

SEP 2
Young Shik Kim (Scientific Director, Gastrointestinal Research Laboratory, University of California, San Francisco, USA)
Colorectal cancer and metastasis: role of mucin glycoproteins
Organized by Pathology Division

 12
Joseph S. Beckman (Professor, Department of Anesthesiology, The University of Alabama at Birmingham, USA)
Understanding how mammalian cell survive or undergo apoptosis after oxidative attack by peroxynitrite
Organized by Investigative Treatment Division

 30
Sara Sukumar (Associate Professor, Johns Hopkins Oncology Center, USA)
Genetics of breast cancer: role of telomerase and HOX genes
Organized by Carcinogenesis Division

OCT 13
Shirish Shenolikar (Associate Professor, Duke University Medical Center, USA)
Protein phosphatase inhibitor-1, a gatekeeper of cyclic AMP signaling pathways
Organized by Carcinogenesis Division

 14
Edward Sausville (Chief, Cancer Therapy Evaluation Program, Department of Cancer Treatment, National Cancer Institute)
New Drug Screening in NCI
Organized by Pharmacology Division

 21
David S. Ettinger (Professor, Department of Oncology Johns Hopkins Oncology Center)
New standard chemotherapy against NSCLC and SCLC
Organized by Pharmacology Division

Susan Arbuck (Head, Development Chemotherapy Section, Cancer Therapy Evaluation Program, Department of Cancer Treatment, National Cancer Institute)
Development of new drugs in NCI-DCT
Organized by Pharmacology Division

Takuma Hayashi (Research Fellow, Whitehead Institute, MIT, Cambridge, MA, USA) Connection between cell cycle and transcription: involvement of transcription factors RelA and Tat in cell cycle control
Organized by Biochemistry Division

 22
Susan Arbuck (Head, Development Chemotherapy Section, Cancer Therapy Evaluation Program, Department of Cancer Treatment, National Cancer Institute)
New NCI-CTC
Organized by Pharmacology Division

 23
Susan Arbuck (Head, Development Chemotherapy Section, Cancer Therapy Evaluation Program, Department of Cancer Treatment, National Cancer Institute)
New methodologies in phase I study design
Organized by Pharmacology Division

 27
Harvey M. Chochinov (Associate Professor, Department of Psychiatry and Medicine, University of Manitoba, Canada)
Desire for death in the palliative care setting: Canadian/American perspective
Organized by Psycho-Oncology Division

NOV 5
Alessandro Weisz (Professor, Institute of Seneral Pathology and Oncology Second University of Napics Napoli, Italy)
Cell cycle control by nuclear receptors
Organized by Investigative Treatment Division

Gunnar Steineck (Associate Professor, Clinical Epidemiology, Karolinska Hospital, Sweden)
Heterocyclic amines and human cancer: a population based study in Stockholm, Sweden
Organized by Cancer Prevention Division

 13
Gokul Das (Professor, Department of Molecular Biology, The University of Texas Health Science Center at Tyler, USA)
Apoptosis and chemo-sensitivity in cancer cells differing in p53 status
Organized by Carcinogenesis Division

Michael J. Plewa (Professor, Department of Microbiology, University of Illinois at Urbana-Champaign, USA)
Activation of environmental aromatic amine promutagens by plant
Organized by Cancer Prevention Division

 17
Massimo Di Rosa (Professor, Department of Experimental Pharmacology Ra Faculty of Pharmacy University of Napolis "FEDERICO II", Italy)
Nitric oxide and inflammation
Organized by Investigative Treatment Division

 21
Barbara Demeneix (Professor, CNRS 90 Laboratory of Physiology, National Museum of Natural History, France)
Non-viral gene transfer into the mammalian brain
Organized by Genetics Division

 25
Alex J. van der Eb (Professor, Sylvius Laboratory Department of Medical Biochemistry University of Leiden, Netherlands)
The viral protein apoptin induces apoptosis in human tumor and transformed cells, but not in normal diploid cells
Organized by Carcinogenesis Division

 27
Ze'ev Ronai (Associate Professor, The Ruttenberg Cancer Center, Mount Sinai School of Medicine, USA)
Dual function JNK: a redox regulated kinase and ubiquitination targeting protein
Organized by Carcinogenesis Division

 28
Annette Krage-Larsen (Research Director, Gustave Roussy Institute, French National Center for Scientific Research, France)
DNA topoisomerases as repair enzymes: mechanism(s) of action and regulation by p53
Organized by Pharmacology Division

N. S. B. Thomas (Senior Lecturer, Department of Haematology, University College London Medical School, England)
Cell cycle control in human haemopoietic cells and abnormalities in leukaemia
Organized by Biology Division
DEC 2
Annette Krage-Larsen (Research Director, Gustave Roussy Institute, French National Center for Scientific Research, France)
The influence of the oncogene suppressor protein p53 on the sensitivity of tumor cells to DNA topoisomerase inhibitors: implication for response prediction and gene therapy
Organized by Pharmacology Division

 3
Serge Fermandjian (Head, Department of Structural Biology and Pharmacology, Gustave Roussy Institute, France)
Structural aspects of the responsive element (CRE and TRE) recognition by bZIP proteins
Organized by Biophysics Division

 4
Ethel Moustacchi (Chief, Curie Research Institute, Paris, France)
Impaired DNA repair in cancer patients with abnormal reactions to radiation therapy
Organized by Genetics Division

 11
Yoshiki Hotta (Director, National Institute of Genetics)
Genetic and molecular analysis of neuronal cell differentiation and neuronal network formation in drosophila
Organized by Carcinogenesis Division

 19
Walter Birchmeier (Professor, Max-Delbruck-Center for Molecular Medicine, Germany)
The role of catenins/armadillo in cell adhesion and signal transduction
Organized by Pathology Division