Monthly Seminars of the National Cancer Center
Research Institute, 1998


Jan 19
Kazuya Shinmura (Biology Division)
Isolation and characterization of the hOGG1 gene that is involved in the excision repair of 8-hydroxyguanine in DNA

Kenji Suzuki (Investigative Treatment and Thoracic Oncology Divisions)
Genetic analyses in lung cancer patients with extreme clinicopathological features
Koichi Benjamin Ishikawa (Cancer Information and Epidemiology Division)
Development of integrated patient information infrastructure with support for institutional cancer registry in National Cancer Center

Feb 6
Hitoshi Ichikawa (Radiobiology Division)
Dual functions of the FUS (TLS)-ERG chimeric transcription factor involved in t(16;21) acute myeloid leukemia
Chifumi Kitanaka (Biophysics Division)
A functional role for death proteases in Myc-mediated apoptosis
Hiroki Sasaki (Genetics Division)
Structural analysis of 11q13 and 17q12 amplicon including genes, core regions and joint DNAs in human cancer

Mar 16
Weimin Ye (Cancer Information and Epidemiology Division)
Mortality and Cancer Incidence in Misasa, a Spa Area in Japan with a High Radon Background
Kazuo Sugiyama (Virology and Glycobiology Division)
Genetic Analysis of the Hepatitis C Virus (HCV) Genome from HCV-infected Human T Cells
Mitsuko Masutani (Biochemistry Division)
Function of Poly(ADP-ribose) Polymerase: Gene-disruption Study in Mice

Apr 20
Masahiko Shiraishi (Oncogene Division)
The comprehensive isolation of hypermethylated CpG islands in human adenocarcinomas of the lung
Yasushi Takahama (Genetics Division)
Molecular cloning and functional analysis of cDNA encoding a rat leukemia inhibitory factor: towards generation of pluripotent rat embryonic stem cells
Tesshi Yamada (Pathology Division)
Identification of semaphorin E as a non-MDR drug-resistance gene in human cancers

May 18
Toshie Gamou (Radiobiology Division)
The partner gene of AML1 in t(16;21) myeloid malignancies is a novel member of the MTG8(ETO) family
Kohji Noguchi (Biophysics Division)
Effect of UV-irradiation on myc family gene-mediated apoptosis
Hitoyasu Futami (Growth Factor Division)
Clinical importance of DNA testing in multiple endocrine neoplasia type 2 (MEN 2) and sporadic medullary thyroid carcinoma (MTC)

Jun 15
Seiichiro Yamamoto (Cancer Information and Epidemiology Division)
Application of new statistical method combining aggregated and individual data
Mitsuaki Maeda (Experimental Pathology and Chemotherapy Division)
Attenuation of the cytotoxicity of antitumor alkylating agents and anti-angiogenic activity of diaminotriazines
Kazuto Nishio (Pharmacology Division)
b3-tubulin is a possible determinant for sensitivity to an antimitotic agent, E7010

Jul 13
Mami Takahashi(Cancer Prevention Division)
Altered expression of mutated b-catenin and inducible nitric oxide synthase in rat colon tumors induced by azoxymethane (AOM)
Masachika Tani (Biology Division)
Isolation of genes involved in metastasis of mouse melanoma
Nobuyuki Matsumoto (Genetics Division)
Cloning of the cDNA for a new human zinc-finger protein defines a group of closely related KrŸppel-like transcription factors

Sep 21
Satoshi Sasaki (Epidemiology and Biostatistics Division)
Dietary intervention study for high risk population of gastric cancer
Yoichi Taya (Biology Division)
Regulation of p53 function by phosphorylation
Yosuke Uchitomi (Psycho-Oncology Division)
Depression in patients with cancer: Prevalence, diagnosis, and treatment

Oct 19
Hideo Kimura (Investigative Treatment Division)
Characterization of NO-mediated activation of VEGF gene transcription
Hitoshi Tsuda (Pathology Division)
Sites of chromosome 16 breakage and der(16)t(1;16) /der(1;16) in human breast carcinoma: clinicopathological and pathogenetic significance
Kouichi Shinohara (Pharmacology Division)
Evidence for the presence of NK-like T cells in NK1.1-positive and -negative mouse strains

Nov 16
Yoshihide Kinjo (Cancer Information and Epidemiology Division)
Risk evaluation of multiple exposures to exogenous factors
Masahiko Nezu (Genetics Division)
Identification of a novel promoter of the c-ERBB-2 gene and a novel amplified gene in a core amplified region of the 17q12 locus
Atsushi Ishii (Virology and Glycobiology Division)
Molecular characterization of ganglioside GM3 synthase (Sialyltransferase-I)

Dec 21
Toshihiko Tsukada (Growth Factor Division)
Mutational and evolutionary study of the MEN1 gene and its clinical implications
Toshihiko Kawamori (Cancer Prevention Division)
Chemoprevention of cancers by cyclooxygenase-2 (COX-2) selective inhibitors Hirokazu Fukuda (Biochemistry Division)
Possible implication of DNA structure and binding proteins in Pc-1 minisatellite stability