Project Index Arranged by Category

Chemical and radiation carcinogenesis

Multistep Genetic Alterations in Colon Carcinogenesis of Rats Induced by PhIP

Exploration of Candidate Susceptibility Genes for Colon Carcinogenesis by PhIP

Characterization of Carcinogen Susceptibility of Human c-Ha-ras Proto-oncogene Transgenic Rats

Isolation of a Putative Target Gene for the Ras Signaling Cascade in Tumor Cells from the Hras128 Rat

Functional Analysis of Cancer-related Genes

The role of mitochondria in the cell suicide system

PBTA-type Mutagens in River Water

Comutagenic Action of b-Carbolines

Spore Dosimetry of Solar-UV Radiation

Cancer Susceptibility and the Rat Genome

Environmental Carcinogens and Cancer

Chemoprevention

Cancer Chemoprevention by Lactoferrin and Other Plant Factors

Analysis of Anti-metastatic and Anti-Carcinogenesis Activity of Bovine Lactoferrin (bLF) in Mice

Search for Cancer Enhancing and Suppressing Substances

Viral carcinogenesis

Viral Carcinogenesis: Hepatitis C Virus (HCV) Replication in vitro

Oncogenes and suppressor genes

Genetic Alterations in Human Cancers

Functional Analysis of Cancer-related Genes

Molecular signaling for Myc-mediated apoptosis

Molecular Structures and Functions of Signal Adaptor (Docking) Proteins Involved in Malignant Transformation

Generation of conditional Cyclin D1 transgenic mice

Identification of novel tumor suppressor gene TSLC1 in human non-small cell lung cancer on chromosomal band 11q23.2

Tumor biology, invasion and metastasis

Molecular and Cellular Mechanisms of Cancer Invasion and Metastasis

Molecular Mechanisms of the Induction of Minisatellite Mutations

Role of Poly(ADP-ribose) Polymerase-1 in Carcinogenesis

Lack of Parp-1 Confers Tumor Phenotype and Trophoblast Differentiation

Other Studies

Isolation and Characterization of Metastasis-associated Genes

Downstream target genes of AML1

Biological Functions of Glycoconjugates in Cancer Cells

Flt-1 promoter as a possible marker for endothelial precursor cells

Test for Fused-cell Origin of Tumors

Cancer-Stromal Interaction and Its Clinical Implications

Clinicopathological Study of Atypical Adenomatous Hyperplasia (AAH) as a Precancerous Lesion of Lung Adenocarcinoma

Biochemical and Molecular Bases of Induced Tolerance to Nutrient Starvation

Analysis of constitutive tolerance of cancer cells to nutrient-starvation

Immunology

Anti-Tumor Immunity of NK-Like T Cells

Detection of Thioredoxin (TRX) in Patients with Gastric Cancer

Immunotherapy and molecular therapeutics for Cancer

Development of Novel cDNA Selection Method Using Adenovirus Vector

Growth factors, cytokines and hormones

Analysis of Tumor-regressing Factor

Pathogenesis of Cancer Cachexia

Cloning New Hematopoietic Factors for Stem Cell Growth from Stromal Cells

Cytotoxic Factors Present in Butterflies

Detection of spatial localization of Hst-1/Fgf-4 gene expression in brain and testes from adult mice

Functional analysis of HST-1/FGF-4 in spermatogenesis

Diagnosis and prognostic factors

Molecular Diagnosis of Biological Aggressiveness of Human Cancers

Clinicopathological Studies

New Modalities for Cancer Diagnosis

Familial Cancer Syndromes: Basic and Clinical Approaches

Clinicopathological Studies on Various Cancers

Epidemiological and biostatistical support for basic and clinical research

Chemotherapy and radiation therapy

Anti-metastatic and Anti-tumor Activities of Diaminotriazine Derivative (4PyDAT) in Mice

Biological and Biochemical Pharmacology

Drug Resistance

Evaluation of Histopathological Factors in the Treatment of Cancer

Gene therapy

A method to augment gene delivery for DNA vaccination through atelocollagen

Polyethylenimine-Based Gene Delivery into Peritoneal Dissemination

Gene Therapy for Colon Cancer using Antisense K-ras RNA

Epidemiology

Genetic Factors for Familial Aggregation of Gastric Cancer

Epidemiological Studies

Foods and Nutrients in the Etiology of Human Cancer (Nutritional Epidemiology)

Environmental and Genetic Interaction in the Etiology of Human Cancer (Molecular Epidemiology)

An Epidemiological Evaluation of Cancer Prevention

Epidemiological and biostatistical support for basic and clinical research

Human genome

Genetic Alterations in Human Cancers

Functional Diversities among Polymorphic Base Excision Genes

Genome Analysis and Genetic Alterations in Human Cancers

Establishment of Efficient Methods for RNA and DNA Amplification

Localization of a prostate tumor suppressor gene on chromosomal band 10p15

Investigation of the Genetic Basis of Cancer Susceptibility of Individuals

Cancer information and biometry

Molecular mechanism of stop codon recognition

Collection and Analysis of Cancer Databases

JCOG Data Center

WHO Collaborating Centre for Reference on Smoking and Health

Infection, inflammation and carcinogenesis

Search for Cancer Enhancing and Suppressing Substances

High alcohol dehydrogenase activity of normal oral microflora, Neisseria

Studies on tumor progression

Genetic and epigenetic alterations

Alteration of DNA methylation in multistage carcinogenesis

Multistep Genetic Alterations in Colon Carcinogenesis of Rats Induced by PhIP

Molecular Mechanisms of the Induction of Minisatellite Mutations

Genetic Alterations in Human Cancers

Isolation and Characterization of Metastasis-associated Genes

Functional Diversities among Polymorphic Base Excision Genes

Genetic Factors for Familial Aggregation of Gastric Cancer

Gene amplification in human cancer

WNT Signaling Pathway Implicated in Carcinogenesis

Other genes implicated in carcinogenesis

Epigenetic Alterations in Cancer

Analysis of Genetic Alterations in Human Cancers

Comprehensive Isolation of CpG Islands Methylated in Human Adenocarcinomas of the Lung

Molecular Mechanism of Gene Silencing by CpG Island Methylation

Studies on tumor progression

Psycho-Oncology

Psychiatric Epidemiology of Depression and Other Forms of Psychological Distress in Cancer Patients

Psychiatric Intervention for Depression and Other Forms of Psychological Distress in Cancer Patients

Refractory Symptoms in Advanced Cancer