Project Index Arranged by Category

Chemical and radiation carcinogenesis

Genetic Alterations in Rat Colon Cancers Induced by PhIP

Exploration of Susceptibility Genes for Colon Carcinogenesis by PhIP

Involvement of Poly(ADP-ribose) Metabolism in Carcinogenesis

Characterization of Carcinogen Susceptibility of Human c-Ha-ras Proto-oncogene Transgenic Rats

Studies on the Association Ability of Metallophthalocyanine Complexes with Polycyclic Aromatic Carcinogens

PBTA-type Mutagens in River Water

Mutagens Formed from Norharman with Aromatic Amines

Cancer Susceptibility and the Rat Genome

Enhanced Skin Carcinogenesis in Cyclin D1 Conditional Transgenic Mice

Chemoprevention

Anti-carcinogenesis and Anti-metastasis of Bovine Lactoferrin (bLF)

Cancer Chemoprevention by Ferulic Acid Derivatives and Other Compounds

Search for Cancer Suppressing Substances

Viral carcinogenesis

Viral Carcinogenesis: Hepatitis C Virus (HCV) Replication in vitro

Oncogenes and suppressor genes

Genetic Alterations in Human Cancers

Functional Analysis of Cancer-related Genes

Genetic Factors for Multiple Primary Cancers

Molecular signaling for c-Myc-mediated apoptosis

Caspase-independent non-apoptotic programmed cell death and its pathophysiological significance

Multiple Endocrine Neoplasia

Genome Analysis and Genetic Alterations in Human Cancers

Identification of a novel tumor suppressor gene, GDM

WNT signaling pathway implicated in carcinogenesis

Phosphorylation of p53

A Novel ATM Family

RB Proteins and Cyclin-dependent Kinases

DNA Methylation and Cancer

Enhanced Skin Carcinogenesis in Cyclin D1 Conditional Transgenic Mice

HST-1/FGF-4 acts as a survival factor for germ cells

Identification of a novel tumor suppressor gene TSLC1 in human lung cancer

Isolation of candidate tumor suppressor genes homologous to the TSLC1

Localization of a prostate tumor suppressor gene on chromosomal band 10p15

A comprehensive catalog of CpG islands specifically methylated in human lung adenocarcinomas for the identification of tumor suppressor genes

The molecular mechanism of gene silencing in cancer cells by CpG island methylation

The AML1 Complex contains leukemia-associated factors

Regulation of MLL by Processing

Establishment of intestinal epithelial cells capable of inducing stabilized beta-catenin

Gene expression profiling of beta-catenin mediated gene transactivation

Tumor biology, invasion and metastasis

Molecular and Cellular Mechanisms of Cancer Invasion and Metastasis

Involvement of Poly(ADP-ribose) Metabolism in Carcinogenesis

Other Studies

Isolation and Characterization of Metastasis-associated Genes

Establishment of a Human Xenograft Derived from an Inflammatory Breast Cancer Showing Vasculogenic Mimicry

The AML1 transcription factor complex

Biological Functions of Signal Docking Proteins in Formation and Metastasis of Cancers

Single Nucleotide Instability

Cancer-Stromal Interaction and Its Clinical Implication

Multistep Carcinogenesis of Lung Adenocarcinoma.

Biochemical and Molecular Basis of Cellular Responses to Insufficient Blood Supply

Immunology

Anti-tumor Immunity of Cytotoxic T Cells, NKT Cells and Dendritic Cells

Detection of Thioredoxin (TRX) in Patients with Gastric Cancer

Cancer-Specific Immunotherapy

Growth factors, cytokines and hormones

Pathogenesis of Cancer Cachexia

Cloning New Hematopoietic Factors for Stem Cell Growth from Stromal Cells

Cytotoxic Factors Present in Butterflies

HST-1/FGF-4 acts as a survival factor for germ cells

Diagnosis and prognostic factors

Molecular Diagnosis of Biological Aggressiveness of Human Cancers

Clinicopathological Studies

Cancer Peptidomics and Tumor Marker Discovery

Proteomic Analysis using two-dimensional differential gel electrophoresis (2D-DIGE)

High-throughput protein identification by mass spectrometry

Clinicopathological Studies on Various Cancers

Epidemiological and biostatistical support for basic and clinical researches

Chemotherapy and radiation therapy

Biological and Biochemical Pharmacology

Drug Resistance

Evaluation of Histopathological Factors on the Treatment for Cancer

Development of new cancer therapies

Gene therapy

Atelocollagen-based Gene Transfer in Cells

Development of Novel cDNA Selection Method Using an Adenovirus Vector

Polyethylenimine-Based Gene Delivery into Peritoneal Dissemination

Gene Therapy for Cancer

Epidemiology

Epidemiological Studies

Foods and Nutrients in the Etiology of Human Cancer (Nutritional Epidemiology)

Environmental and Genetic Interaction in the Etiology of Human Cancer (Molecular Epidemiology)

An Epidemiological Evaluation of Cancer Prevention

Epidemiological and biostatistical support for basic and clinical researches

Human genome

Functional Diversity among Polymorphic Base Excision Genes

Amplification of RNA from Cells Collected by Laser-capture Microdissection

Towards Personalized Cancer Care By Expression Profiling

Investigation of the Genetic Basis of Cancer Susceptibility

Cancer information and biometry

Molecular mechanism of stop codon recognition

Collection and Analysis of Cancer Databases

JCOG Data Center

Research and Development of Clinical Support Systems

WHO Collaborating Centre for Reference on Smoking and Health

Infection, inflammation and carcinogenesis

Drug design-tool using VR technology

Search for Cancer Suppressing Substances

Studies on tumor progression

Genetic and epigenetic alterations

Alteration of DNA methylation in multistage carcinogenesis

Genetic Alterations in Rat Colon Cancers Induced by PhIP

Molecular Mechanisms Underlying Induction of Minisatellite Mutations

Involvement of an Orphan Nuclear Receptor in Tumorigenesis

Molecular Functions of Ganglioside GM3 in Cancer Cells

Psycho-Oncology

Psychiatric Epidemiology of Depression and Other Psychological Distress in Cancer Patients

Psychiatric Intervention for Depression and Other Psychological Distress in Cancer Patients

Refractory Symptoms in Advanced Cancer