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Project Index Arranged by Category

Chemical and radiation carcinogenesis

Exploration of Susceptibility Genes for Colon Carcinogenesis by PhIP

Multistep Genetic Alterations in Colon Carcinogenesis Induced by PhIP

Analysis of the Carcinogenic Process Using Transgenic (Tg) Rats

Risk Assessment Study and Others

Cancer Susceptibility and the Rat Genome

Generation of Conditional Cyclin D1 Transgenic Mice

Mutagens in River Water

Mutagens Formed from Norharman with Aromatic Amines

Research for the Mechanism of the "Field Cancerization" Phenomenon in the Upper Aerodigestive Tract

Chemoprevention

Prevention of Carcinogenesis and Anti-metastasis by Bovine Lactoferrin (bLF)

Prevention of Carcinogenesis

Search for Cancer Suppressing Substances

Viral carcinogenesis

Immortalization of Human Cells by HPV

Transforming Activity of HPV Genes

HCV RNA Replicon

Cell Cycle Regulation of DNA Replication in Mammalian Cells

Oncogenes and suppressor genes

Isolation of a Noble Lung Cancer Suppressor Gene, MYO18B

Genetic and Epigenetic Alterations of Tumor Suppressor Genes

Molecular Mechanism of Chromosome 9p21 Deletions in Lymphoid Leukemia

Functional Analysis of Cancer-related Genes

Genetic Testing for Familial Cancer Syndrome

MLL Is Processed into 2 Fragments with Opposite Transcriptional Properties

MOZ Is a Potent Co-activator for AML1 and p53

Gene Expression Analysis of Leukemia Using Microarrays

Apoptosis Induction by p53

Phosphorylation of Mdm2

Single Nucleotide Instability

Generation of Conditional Cyclin D1 Transgenic Mice

Cloning of Leukemia-associated Genes

Positional Cloning of Tumor Suppressor Genes of Chromosome 11q

The Comprehensive Isolation of CpG Islands Methylated in Human Lung Cancer

Multiple Endocrine Neoplasia Type 1 and Other Heritable Endocrine Diseases

Involvement of Orphan Nuclear Receptor in Tumorigenesis

Inactivation of a Tumor Suppressor Gene TSLC1 in Human Cancers

Characterization of TSLC1 Protein and Its Cascade of Tumor Suppression

Analysis of Genetic Alterations in Human Cancers

Tumor biology, invasion and metastasis

Mechanisms of Cancer Invasion and Metastasis

Molecular Background of Biological Characteristics of Human Cancers

Functional Analyses of DNA/RNA- Binding Protein, LRP130

Role of Poly(ADP-ribose) Metabolism in Carcinogenesis

Isolation of a Noble Lung Cancer Suppressor Gene, MYO19B

Establishment of High- and Low-metastatic Human Cancer Cell Lines

A Xenograft Derived from an Inflammatory Breast Cancer Showing Vasculogenic Mimicry

The Role of Caspase-independent Non-apoptotic Programmed Cell Death in Tumor Suppression

The Lon Protease

Biological Roles of Signal Docking Proteins Involved in Transformation and Migration of Tumor Cells

Cell Cycle Regulation of DNA Replication in Mammalian Cells

Small Cell Lung Cancer Cell Lines with Neuron-like Processes

Generation of Conditional Cyclin D1 Transgenic Mice

Therapeutic Use of Hepatic Cells Differentiated from embryonic stem cells ES Cells

Suppression of Intestinal Polyposis in Mdr1-deficient ApcMin/+ Mice

Transcriptomic and Proteomic Analyses of Early Colorectal Carcinogenesis

Cancer-Stromal Interaction and Its Clinical Implication

Biochemical and Molecular Basis of Cellular Responses to Insufficient Blood Supply

Immunology

Anti-tumor Immunity of Immunocompetent Cells and Allogeneic Transplantation Immunotherapy

Immune Surveillance and Tumor Immunity at the Lipid Microdomains

Translational Research of Cancer-specific Immunotherapy

Analysis of the Hematopoietic Microenvironment

Growth factors, cytokines and hormones

Megakaryocyte Development and Platelet Formation

Analysis of the Hematopoietic Microenvironment

Functional Analysis of HST-1/FGF-4 on Spermatogenesis

Cytotoxic Factors Present in Butterflies

Pathogenesis of Cancer Cachexia

Toxic Proteins

Diagnosis and prognostic factors

Clinicopathological Studies

Genetic and Epigenetic Alterations of Tumor Suppressor Genes

A Peptidomic Approach to Tumor Marker Discovery

Microarray Analysis of Peritoneal Wash Samples to Predict Recurrence of Gastric Cancer

Construction of a Database for Two-dimensional Gel Electrophoresis

Application of Laser Microdissection for Proteomic Studies of Cancer

Clinicopathological Studies on Various Cancers

Chemotherapy and radiation therapy

Establishment of High- and Low-metastatic Human Cancer Cell Lines

Biological and Biochemical Pharmacology

JCOG Data Center

Drug Design-tool Using VR Technology

Evaluation of Histopathological Factors on the Treatment for Cancer

Drug Delivery Systems in Cancer Chemotherapy

Gene therapy

A Method to Augment Gene Delivery in vivo through Atelocollagen

Gene Therapy for Pancreatic Cancer

Gene Therapy for Androgen-independent Prostate Cancer

Construction of a New Strategy of Gene Therapy

Epidemiology

Genetic Polymorphisms and Lung Cancer Susceptibility

Functional Analysis of Cancer-related Genes

Epidemiological Studies

Population-based Prospective Study (JPHC Study)

Gastric Cancer Prevention Trials (Hiraka Study)

Epidemiological Study on Japanese Brazilians (Sao Paulo - Japan Cancer Study)

Epidemiological Study on Endocrine Disrupting Chemicals

Epidemiological and Biostatistical Support for Basic and Clinical Research Programs

Human genome

Isolation of a Noble Lung Cancer Suppressor Gene, MYO20B

Molecular Mechanism of Chromosome 9p22 Deletions in Lymphoid Leukemia

Genetic Polymorphisms and Lung Cancer Susceptibility

Functional Analysis of Cancer-related Genes

A New Whole Genome Amplification Method for Genome Research

Molecular Basis of Cancer Susceptibility

Transcription Factor Database and Related Tools

Development of Novel cDNA Selection Method Using an Adenovirus Vector

Genome-Wide Detection of Chromosomal Imbalances in Tumors

Heterogeneity in the Modification of Chromatin Components in Cancer Cells

Investigation of the Genetic Basis of Cancer Susceptibility

Cancer information and biometry

Collection and Analysis of Cancer Databases

WHO Collaborating Centre for Reference on Smoking and Health

Infection, inflammation and carcinogenesis

Search for Cancer Suppressing Substances

Role of Nitric Oxide (NO) in Bile Duct Injury

Genetic and epigenetic alterations

Epigenetic and Genetic Alteration during Multistage Carcinogenesis

Multistep Genetic Alterations in Colon Carcinogenesis Induced by PhIP

Molecular Mechanisms for Maintenance of G-rich Short Tandem Repeats

Isolation of a Noble Lung Cancer Suppressor Gene, MYO21B

Genetic and Epigenetic Alterations of Tumor Suppressor Genes

Molecular Mechanism of Chromosome 9p23 Deletions in Lymphoid Leukemia

Studies on Gene Amplification in Human Cancer

WNT Signaling Pathway

Other Genes and Molecules Relevant to Cancer Biology

DNA Methylation and Cancer

Other Research Projects

Cloning of Leukemia-associated Genes

Positional Cloning of Tumor Suppressor Genes of Chromosome 11q

Genome-Wide Detection of Chromosomal Imbalances in Tumors

Psycho-Oncology

Depression in Cancer Patients

Other Psychological Distress in Cancer Patients

Refractory Symptoms in Advanced Cancer