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Chemical and radiation carcinogenesis
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Susceptibility to Colon Carcinogenesis
Multistep Genetic Alterations in Colon Carcinogenesis Induced by PhIP
PolyADP-ribosylation and Carcinogenesis
Analysis of the Carcinogenic Process Using Transgenic Rats
Risk Assessment and Other Studies
Cancer Susceptibility and the Rat Genome
Environmental Factors and Cancer
Mutagens in River Water and Surface Soil
Mutagens Formed from Norharman with Aromatic Amines
Cytotoxic Factors Present in Butterflies
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Chemoprevention
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Anti-carcinogenesis
Prevention of Carcinogenesis and Anti-metastasis by Bovine Lactoferrin (bLF)
Search for Cancer Suppressing Substances
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Viral carcinogenesis
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Immortalization of Human Cells by HPV
HCV RNA Replicon and Application of an LCM-array for Cancer
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Oncogenes and suppressor genes
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Molecular Basis of Multistage Lung Carcinogenesis
Functional Analysis of Cancer-related Genes
Identification and Characterization of p53-target Genes
Molecular Mechanism of Stop Codon Recognition
Functional Analysis of Normal and Activated Ret Oncogenes in Human Cancers
PML Interacts with AML1 and Regulates Transcription of Their Target Genes
PU.1 Regulates Expression of SHIP in Hematopoietic Cells
Rearrangement of MOZ in Pediatric tMDS with t(2;8)(p23;p11)
Expression Analysis of The Gasdermine Gene Family
Characterization of The Biological Function of The SYT-SSX1 Gene in Synovial Sarcomas
Medical Bioinformatics
Methods for Generation of Phospho-specific Antibodies
Mutation of ATM in MLL
Phosphorylation of Mdm2 by ATR
Phosphorylation of p73 by CDK
2-Aminopurine and p53
Genome-Wide Detection of Chromosomal Imbalances in Tumors
Mechanism to Regulate Neutrophilic Differentiation
Analysis of Effect of NLK on Cell Growth
Multiple Endocrine Neoplasia Type 1
Involvement of Aberrant Splicing in Tumorigenesis
Characterization of the TSLC1 Protein and Its Cascade of Tumor Suppression
Towards the Elucidation of the TSLC1 Function in Model Animals
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Tumor biology, invasion and metastasis
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Mechanisms of Cancer Invasion and Metastasis
Molecular Background of the Biological Characteristics of Human Cancers
Molecular Mechanism for Maintenance of G-rich Short Tandem Repeats
Functional Analyses of Protein Phosphatase 5
Roles of LRP130 and Tudor-SN/p100 in the Growth of Cancer Cells
Cell Migration
Genes Involved in Cancer Metastasis
Positive and Negative Regulation of Neural Apoptosis
Dysregulation of dNTP Pools in Cancer and Its Strategic Regulation
Roles of Tyrosine Kinases and their Substrates in Transformation and Migration of Tumor Cells
Involvement of the Eph Receptor Tyrosine Kinase and Ephrin Ligand in the Regulation of Cell-to-cell Adhesion
Cell Cycle Regulation of DNA Replication in Mammalian Cells and Its Implication in Carcinogenesis
Actinin-4 Enhances Cell Motility and Mediates Lymphatic Spread of Colorectal Cancer
Alternative Splice Variant of Actinin-4 in Small Cell Lung Cancer
Cancer-Stromal Interaction
Role of Nitric Oxide (NO) in Tumor Progression
Biochemical and Molecular Basis of Cellular Responses to Insufficient Blood Supply
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Immunology
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Anti-tumor Immunity of Immunocompetent Cells and Allogeneic Transplantation Immunotherapy
Immune Surveillance and Tumor Immunity at the Lipid Microdomains
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Growth factors, cytokines and hormones
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Isolation of Membrane and Secreted Proteins from Hematopoiesis-Supporting Stromal Cells
Direct Hepatic Fate Specification from Embryonic Stem Cells
Pathogenesis of Cancer Cachexia
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Diagnosis and prognostic factors
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Clinicopathological Studies
A Peptidomic Approach to Identify Secretory Peptides
Identification of Proteomic Signatures That Predict the Biological Behavior of Cancer Cells
Development of Multi-dimensional Liquid Chromatography for Plasma Biomarker Discovery
Gene Expression Analysis of AML
Gene Expression Analysis of Neuroblastoma
Clinicopathogical Studies on Various Cancers
Noninvasive Diagnostic Test for Colorectal Cancer
Development of innovative Diagnostic and Therapeutic Methods for Squamous Cell Carcinoma in situ in Head and Neck Mucosal Sites
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Chemotherapy and radiation therapy
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Molecular Correlative Study and Clinical Pharmacology
JCOG Data Center
Evaluation of Cancer Phenotypes on the Treatment for Cancer
Drug Delivery Systems (DDS) in Cancer Chemotherapy
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Gene therapy
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New Therapeutic Strategies for Cancer Therapy
Basic Studies on Gene Therapy
Antisense Oligos against HST-1/FGF-4 Suppresse Tumorigenicity of Human Germ Cell Tumors
Atelocollagen-mediated Effective Delivery of Synthetic Small Interfering RNAs in Mammalian Cells and Animals
IFN-a Gene Therapy against Pancreatic Cancer
Combination of Immune Gene and Cell Therapy
Development of a Fiber-modified Adenovirus Vector Library
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Epidemiology
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Cancer Registries and Surveillance
Epidemiological Studies
Population-based Prospective Study (the JPHC Study)
Gastric Cancer Prevention Trials (Hiraka Study)
Epidemiological Study on Japanese Brazilians (Sao Paulo - Japan Cancer Study)
Epidemiological Study on Endocrine Disrupting Chemicals
Other Epidemiological Studies
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Human genome
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Genes Involved in the Susceptibility to Lung and Gastric Cancers
Global Amplification of Genomic DNA and mRNA
Molecular Basis of Cancer Susceptibility
VR Technology and Transcription Factor Database (TFDB)
Other Research Projects
Investigation of the Genetic Basis of Cancer Susceptibility
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Cancer information and biometry
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WHO Collaborating Centre for Reference on Smoking and Health
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Genetic and epigenetic alterations
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Epigenetic Alteration during Multistage Carcinogenesis
Chromosome 9p21 Deletions in Human Lung Cancer
Genetic Susceptibility in Pediatric Leukemia
Other Studies Relevant to Molecular Carcinogenesis
DNA Methylation and Cancer
The Comprehensive Isolation of CpG Islands Methylated in Human Lung Cancer
Functional Relationship between Gene Silencing and DNA Methylation
The Improvement of the Bisulfite Modification Reaction
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Psycho-Oncology
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Inactivation of a Tumor Suppressor Gene, TSLC1, in Human Cancers
Depression in Cancer Patients
Other Psychological Distress in Cancer Patients
Refractory Symptoms in Advanced Cancer