STATISTICS AND CANCER CONTROL DIVISION

26.STATISTICS AND CANCER CONTROL DIVISION

    The Statistics and Cancer Control division is in charge of conducting data collection, integrated management, analysis and dissemination of cancer information at the national level by means of the following aspects; to support and maintain population-based and hospital-based cancer registries for monitoring cancer occurrence, to conduct descriptive epidemiologic analysis on cancer mortality and incidence; to collect and review information on cancer prevention and early detection; to manage the multi-center cooperative clinical trials data coordinating center (JCOG data center); and to conduct economic evaluation and health services research in cancer care based on clinical information.
Population-Based and Hospital-Based Cancer Registries

    Establishment of a cancer surveillance system in Japan is one of the main objectives in the third term comprehensive 10-year program for Cancer Control. In particular, population-based and hospital-based cancer registries, basic infrastructures for the surveillance system, should be completed urgently in an earlier phase in the program. The Division plays an important roll as a driving force for the standardization and quality improvements of two types of cancer registries; it develops data standards for cancer registration, provides educational programs for cancer registry personnel, develops cancer registry software to provide to prefectural cancer registry offices and hospitals, and disseminates up-to-date information on cancer-registry-related issues through the websites (http://ncrp.ncc.go.jp and http://jcdb.ncc.go.jp). Furthermore, the Division manages the National Cancer Center Hospital Cancer Registry (NCCHCR) and the nation-wide registry for hereditary nonpolyposis colorectal cancer (HNPCC) since 2002 as a collaborative project with the Japanese Research Society for Cancer of Colon and Rectum.
Descriptive and Analytic Epidemiology

    The Division takes charge of descriptive analyses on cancer incidences and mortalities, which are essential to monitor and evaluate the National Cancer Control Program in Japan. Cancer surveillance activities, such as time trends of age-group stratified number of deaths and mortality rates, age adjusted mortality rates, and proportions of mortality to all cancer deaths by cancer sites, are reported ^(295,^296-³⁰⁷⁾. In collaboration with the Japan Public Health Center-based prospective Study, the association of various risk factors and cancer incidence are evaluated such as HTLV-1 vs. all cancer and ⁽³⁰⁸⁾ and fruit consumption vs. lung cancer ⁽³⁰⁹⁾. To investigate the effect of risk factor on future cancer mortality, the relative impact of smoking on lung cancer incidence has been evaluated ⁽³¹⁰⁾.
Collection and Review of Information on Cancer Prevention and Early Detection

    The guidelines for cancer screening have been updated based on new research following the report "Evaluation effectiveness of cancer screening" (Hisamichi S Ed.) published in 2001, through which the guideline development process is standardized. The guideline for colorectal cancer screening is now being revised. The accuracy management of various examinations for cancer screening is promoted by collecting the information from related institutions in all prefectures. Since the compliance of cancer screening in Japan is low compared with Western developed countries, strategies to improve compliance are examined.
Health Services Research in Cancer Care

    The project executed studies in National Cancer Center Hospital, targeted at the operating room and the outpatient chemotherapy center. The former study clarified logistics for cancer surgery and formulated a standard preparation manual for 107 procedure categories, the latter performed revenue analysis using accounting information. The project also took part in refinement of the Japanese casemix classification system (DPC, Diagnosis Procedure Combination) as principal data analyst and published the "DPC porfolio" outlining clinical characteristics for each casemix group using the 2003 study data.
JCOG Data Center

    The Division is running the data coordinating center of the Japan Clinical Oncology Group (JCOG), a nationwide multi-institutional, multi-disease, multi-modality cooperative study group supported by a Grant-in-Aid for Cancer Research and Health Sciences Research Grants from the Ministry of Health, Labour and Welfare, in collaboration with the Society of Japanese Pharmacopoeia. It is currently managing approximately 70 clinical trials. Designing clinical trials ⁽³¹¹⁾, periodical monitoring for data and safety, interim and final analyses are performed for all studies through data management, statistics and clinical teams. A new web-based clinical data management system, which is expected to increase the performance of data management and the quality of data, is now under test. Final results of the phase III study ⁽³¹²⁾, phase II studies ^(313,³¹⁴⁾, and ancillary study of JCOG clinical trial ⁽³¹⁵⁾ have been reported. As an intramural research project, methodological research for data management was also conducted. JCOG data center supports clinical research other than JCOG studies on a consultancy basis ^(316,³¹⁷⁾.
WHO Collaborating Centre for Reference on Smoking and Health

    The National Cancer Center is designated by the World Health Organization as the WHO Collaborating Centre for Reference on Smoking and Health, and the Division takes the responsibility of running the Centre. It will cover the following aspects; to collect and analyze information and data on smoking and health, to be a clearing house for information on smoking and health, and to support implementation of the WHO Framework Convention on Tobacco Control (FCTC), which will be in force at the end of February, 2005.




26.STATISTICS AND CANCER CONTROL DIVISION



	The Statistics and Cancer Control division is in charge of conducting data collection, integrated management, analysis and dissemination of cancer information at the national level by means of the following aspects; to support and maintain population-based and hospital-based cancer registries for monitoring cancer occurrence, to conduct descriptive epidemiologic analysis on cancer mortality and incidence; to collect and review information on cancer prevention and early detection; to manage the multi-center cooperative clinical trials data coordinating center (JCOG data center); and to conduct economic evaluation and health services research in cancer care based on clinical information. Population-Based and Hospital-Based Cancer Registries Establishment of a cancer surveillance system in Japan is one of the main objectives in the third term comprehensive 10-year program for Cancer Control. In particular, population-based and hospital-based cancer registries, basic infrastructures for the surveillance system, should be completed urgently in an earlier phase in the program. The Division plays an important roll as a driving force for the standardization and quality improvements of two types of cancer registries; it develops data standards for cancer registration, provides educational programs for cancer registry personnel, develops cancer registry software to provide to prefectural cancer registry offices and hospitals, and disseminates up-to-date information on cancer-registry-related issues through the websites (http://ncrp.ncc.go.jp and http://jcdb.ncc.go.jp). Furthermore, the Division manages the National Cancer Center Hospital Cancer Registry (NCCHCR) and the nation-wide registry for hereditary nonpolyposis colorectal cancer (HNPCC) since 2002 as a collaborative project with the Japanese Research Society for Cancer of Colon and Rectum. Descriptive and Analytic Epidemiology The Division takes charge of descriptive analyses on cancer incidences and mortalities, which are essential to monitor and evaluate the National Cancer Control Program in Japan. Cancer surveillance activities, such as time trends of age-group stratified number of deaths and mortality rates, age adjusted mortality rates, and proportions of mortality to all cancer deaths by cancer sites, are reported ^(295,^296-³⁰⁷⁾. In collaboration with the Japan Public Health Center-based prospective Study, the association of various risk factors and cancer incidence are evaluated such as HTLV-1 vs. all cancer and ⁽³⁰⁸⁾ and fruit consumption vs. lung cancer ⁽³⁰⁹⁾. To investigate the effect of risk factor on future cancer mortality, the relative impact of smoking on lung cancer incidence has been evaluated ⁽³¹⁰⁾. Collection and Review of Information on Cancer Prevention and Early Detection The guidelines for cancer screening have been updated based on new research following the report "Evaluation effectiveness of cancer screening" (Hisamichi S Ed.) published in 2001, through which the guideline development process is standardized. The guideline for colorectal cancer screening is now being revised. The accuracy management of various examinations for cancer screening is promoted by collecting the information from related institutions in all prefectures. Since the compliance of cancer screening in Japan is low compared with Western developed countries, strategies to improve compliance are examined. Health Services Research in Cancer Care The project executed studies in National Cancer Center Hospital, targeted at the operating room and the outpatient chemotherapy center. The former study clarified logistics for cancer surgery and formulated a standard preparation manual for 107 procedure categories, the latter performed revenue analysis using accounting information. The project also took part in refinement of the Japanese casemix classification system (DPC, Diagnosis Procedure Combination) as principal data analyst and published the "DPC porfolio" outlining clinical characteristics for each casemix group using the 2003 study data. JCOG Data Center The Division is running the data coordinating center of the Japan Clinical Oncology Group (JCOG), a nationwide multi-institutional, multi-disease, multi-modality cooperative study group supported by a Grant-in-Aid for Cancer Research and Health Sciences Research Grants from the Ministry of Health, Labour and Welfare, in collaboration with the Society of Japanese Pharmacopoeia. It is currently managing approximately 70 clinical trials. Designing clinical trials ⁽³¹¹⁾, periodical monitoring for data and safety, interim and final analyses are performed for all studies through data management, statistics and clinical teams. A new web-based clinical data management system, which is expected to increase the performance of data management and the quality of data, is now under test. Final results of the phase III study ⁽³¹²⁾, phase II studies ^(313,³¹⁴⁾, and ancillary study of JCOG clinical trial ⁽³¹⁵⁾ have been reported. As an intramural research project, methodological research for data management was also conducted. JCOG data center supports clinical research other than JCOG studies on a consultancy basis ^(316,³¹⁷⁾. WHO Collaborating Centre for Reference on Smoking and Health The National Cancer Center is designated by the World Health Organization as the WHO Collaborating Centre for Reference on Smoking and Health, and the Division takes the responsibility of running the Centre. It will cover the following aspects; to collect and analyze information and data on smoking and health, to be a clearing house for information on smoking and health, and to support implementation of the WHO Framework Convention on Tobacco Control (FCTC), which will be in force at the end of February, 2005.