Research Activities
Staff scientists of the Pathology Division are also Japanese Board-certified
pathologists, and are engaged in routine pathology work involving diagnosis
of biopsy and surgically resected materials and postmortem examinations at
the National Cancer Center Hospital. The histological heterogeneity of tumors
reflects the stepwise and orderly progression of multistage carcinogenesis
in humans. On the basis of findings from our routine diagnostic work, we develop
scientific ideas and follow them up using a molecular pathological approach,
which can yield potential benefits for patients with cancer. In order to identify
new strategies for carcinogenetic risk estimation, early diagnosis of cancer,
prognostication of patients, and cancer prevention and therapy, we analyze
genome-wide genetic and epigenetic alterations during multistage carcinogenesis
and examine molecular mechanisms for determining the biological characteristics
of human cancers.
Research Projects
List of Papers Published
