Research Activities
Staff scientists of the Division of Molecular Pathology are also Japanese
Board-certified pathologists, who are engaged in routine pathology work involving
diagnosis of biopsy and surgically resected materials and postmortem examinations
at the National Cancer Center Hospital. The histological heterogeneity of
tumors reflects the stepwise and orderly progression of multistage carcinogenesis
in humans. On the basis of findings from our routine diagnostic work, we develop
scientific ideas and follow them up using a molecular pathological approach,
which can yield potential benefits for patients with cancer. In order to identify
new strategies for carcinogenetic risk estimation, early diagnosis of cancer,
prognostication of patients, and cancer prevention and therapy, we perform
multilayer-omics analysis, especially epigenome analysis, during multistage
carcinogenesis and examine molecular mechanisms for determining the biological
characteristics of human cancers.
Research Projects
List of Papers Published 