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Research StaffResearch ActivitiesStaff scientists of the Pathology Division are also Japanese Board-certified pathologists, and are engaged in routine pathology work involving diagnosis of biopsy and surgically resected materials and postmortem examinations at the National Cancer Center Hospital. The histological heterogeneity of tumors reflects the stepwise and orderly progression of multistage carcinogenesis in humans. On the basis of findings from our routine diagnostic work, we develop scientific ideas and follow them up using a molecular pathological approach, which can yield potential benefits for patients with cancer. In order to identify new strategies for carcinogenetic risk estimation, early diagnosis of cancer, prognostication of patients, and cancer prevention and therapy, we analyze genome-wide genetic and epigenetic alterations during multistage carcinogenesis and examine molecular mechanisms for determining the biological characteristics of human cancers.Research Projects
List of Papers Published
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Last Update:2009/04/17 contact |
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