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Research StaffResearch ActivitiesHow does individual cancer develop? How and what types of genomic aberrations are induced by environmental factors and genetic factors during carcinogenesis? Many issues on the mechanisms of cancer development have not been clarified yet. Research in the Biochemistry Division is aimed at elucidation of the mechanisms of carcinogenesis induced by environmental factors, and cancer growth, envisioning contribution to cancer prevention and early diagnosis of cancer. Research in the Biochemistry Division has been conducted, including establishment of a chemical carcinogenesis model in rat stomach using N-methyl-N'-nitro-N-nitrosoguanidine, and discovery of poly(ADP-ribose) and carcinogenic heterocyclic amines.Elucidation of carcinogenesis induced by various environmental and genetic factors is an important issue in establishing strategies for cancer prevention and early diagnosis of cancer, as well as developing new therapeutic strategies. In the Biochemistry Division, studies on the mechanisms of colon cancer development using rat models, genomic aberrations including G-rich short tandem repeats, and roles of microRNA and polyADP-ribosylation reaction in carcinogenesis are being studied from various approaches. Research Projects
List of Papers Published
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Last Update:2010/02/02 contact |
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