National Cancer Center Research Institute

Growth Factor Division

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Research Staff


Research Activities

Numbers of receptor and non-receptor tyrosine kinases are involved in multiple steps of cancer progression. Signals from activated tyrosine kinases are mediated through phosphorylation of substrate molecules to modulate cell characteristics during tumor proliferation and metastasis. The main object of our division is to elucidate the roles of tyrosine phosphorylation of signaling molecules during cancer development. One of our goals of the research is to establish models of the signal therapy of progressed cancer by regulating phosphotyrosine-dependent interactions between signaling molecules.


Research Projects



List of Papers Published




Last Update:2009/01/29
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