Research Activities
This Division focuses on carcinogenic mechanisms, and it is especially
known for its research in epigenetic mechanisms of carcinogenesis. The
Division developed one of the earliest methods for genome-wide screening
method for differences in DNA methylation, designated as MS-RDA (Ushijima
et al., 1997 Ushijima, 2005). The method was successfully used not only
to identify tumor-suppressor genes (Kaneda et al., 2004), but also to
isolate a prognostic marker that is superior to clinically used ones (Abe
et al., 2005) and to establish a novel concept of "epigenetic field
for cancerization" that can be utilized as a cancer risk marker (Maekita
et al., 2006, Nakajima et al., 2006, Ushijima, 2007).
Research Projects
List of Papers Published
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