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HOME > National Cancer Center Research Institute > Each Division > Division of Molecular and Cellular Medicine > Evaluation for Efficacy of Gene Medicine and Differentiation of Stem Cells with in vivo Imaging

Evaluation for Efficacy of Gene Medicine and Differentiation of Stem Cells with in vivo Imaging



Recently, optical imaging technologies for clinical use have been sized down to make them available for non-invasive in vivo imaging for small animals. The development of molecular imaging using luminescence or fluorescence in vitro have facilitated in vivo imaging to detect the molecular events in tumor cells on living animals. "In vivo imaging" and "In vivo molecular imaging" are now being established as a new field of research. Promptness and handiness of the in vivo imaging are rapidly changing the design of the animal experiments not only in cancer research but in the whole of biology. Also, in our laboratory, evaluation of treatments with cancer model studies and imaging for the gene medicine molecule such as siRNA are done by making good use of this imaging device that detects luminescence and fluorescence from the living animals.

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References
1. Cancer Res., 2006, 66:7532-9.
2. Nucleic Acids Res., 2004, 32:e109.
3. Proc. Natl. Acad. Sci. U S A. 2005, 102:12177-82.