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Home > Organization > Divisions and Independent Research Units > Group for Research of Molecular Functions and Targets > Division of Cancer Stem Cell > Research Papers

Research Papers

2017

  1. IshibashiM,NeriS,HashimotoH,MiyashitaT,YoshidaT,NakamuraY,UdagawaH,KiritaK,
    MatsumotoS,UmemuraS,YohK,NihoS,TsuboiM,MasutomiK,GotoK,OchiaiA,IshiiG.
    CD200positivecancerassociatedfibroblastsaugmentthesensitivityofEpidermalGrowthFactorReceptormutation-positivelungadenocinomastoEGFRTyrosinekinaseinhibitors
    SciRep7:46662.doi:10.1038/srep46662,2017
    (PubMedID28429795)
  2. HashimotoH,SudaY,MiyashitaT,OchiaiA,TsuboiM,MasutomiK,KiyonoT,IshiiG.
    Anovelmethodtogeneratesingle-cell-derivedcancer-associatedfibroblastclones
    JCancerResClinOncol10.1007/s00432-017-2409-3,2017
    (PubMedID28364361)

2016

  1. SudaY,NeriS,HashimotoH,HiguchiY,IshibashiM,SuganoM,MasutomiK,TsuboiM,OchiaiA,IshiiG
    Clonalheterogeneityinosteogenicpotentialoflungcancer-associatedfibroblasts:
    promotionaleffectofosteogenicprogenitorcellsoncancercellmigration
    JCancerResClinOncol142:1487-1498,2016
    (PubMedID27119516)
  2. MaidaY,YasukawaM,MasutomiK
    DenovoRNAsynthesisbyRNA-dependentRNApolymeraseactivityofTERT
    MolCellBiol36:1248-1259,2016
    (PubMedID26830230)
  3. NeriS,HashimotoH,KiiH,WatanabeH,MasitomiK,KuwataT,DateH,TsuboiM,
    GotoK,OchiaiA,IshiiG
    Cancercellinvasiondrivenbyextracellularmatrixremodelingisdependentonthe
    propertiesofcancer-associatedfibroblasts
    JCancerResClinOncol142:437-446,2016
    (PubMedID26374424)

2015

  1. LassmannT,MaidaY,TomaruY,YasukawaM,AndoY,KojimaM,KasimV,
    SimonC,DaubC,CarninciP,HayashizakiY,MasutomiK
    TelomerasereversetranscriptaseregulatesmicroRNAs
    IntJMolSci16:1192-1208,2015
    (PubMedID25569094)

2014

  1. YamaguchiS,MaidaY,YasukawaM,KatoT,YoshidaM,MasutomiK
    Eribulinmesylatetargetshumantelomerasereversetranscriptaseinovariancancercells
    PLoSONE9:e112438,2014
    (PubMedID25375122)
  2. KobayashiT,MasutomiK,TamuraK,MoriyaT,YamasakiT,FujiwaraY,
    TakahashiS,YamamotoJ,TsudaH
    Nucleosteminexpressionininvasivebreastcancer
    BMCCancer14:215,2014
    (PubMedID24650343)
  3. MaidaY,YasukawaM,OkamotoN,OhkaS,KinoshitaK,TotokiY,ItoTK,
    MinaminoT,NakamuraH,YamaguchiS,ShibataT,MasutomiK
    InvolvementofTERTinheterochromatinmaintenance.
    MolCellBiol34:1576-1593,2014
    (PubMedID24550003)

2013

  1. MaidaY,KyoS,LassmannT,HayashizakiY,MasutomiK
    Off-TargetEffectofEndogenoussiRNADerivedfromRMRPinHumanCells
    IntJMolSci14:9305-9318,2013
    (PubMedID23629666)

2012

  1. YunokawaM,KoizumiF,KitamuraY,KatanasakaY,OkamotoN,KodairaM,YonemoriK,ShimizuC,AndoM,MasutomiK,YoshidaT,FujiwaraY,TamuraK
    Efficacyofeverolimus,anovelmTORinhibitor,againstbasal-liketriple-negative breastcancercells
    CancerScience103:1665-1671,2012
    (PubMedID22703543)
  2. NakajimaTE,YoshidaH,OkamotoN,NagashimaK,TaniguchiH,YamadaY,ShimodaT,MasutomiK
    NucleosteminandTWISTaspredictivemarkersforrecurrenceafterneoadjuvantchemoth
    erapyforesophagealcarcinoma
    CancerScience103:233-238,2012
    (PubMedID22050045)
  3. HiraiY,MasutomiK,IshikawaF
    KineticsofDNAreplicationandtelomerasereactionatasingle-seededtelomereinhumancells
    GenesCells17:186-204,2012
    (PubMedID22353550)

2011

  1. RosenbluhJ,NijhawanD,ChenZ,WongKK,MasutomiK*,HahnWC*
    RMRPisanon-codingRNAessentialforearlymurinedevelopment
    PLoSONE(*:co-correspondingauthor)6:e26270,2011
    (PubMedID22039455)
  2. JinushiM,ChibaS,YoshiyamaH,MasutomiK,KinoshitaI,Dosaka-AkitaH,
    YagitaH,TakaokaA,TaharaH
    Tumor-associatedmacrophagesregulatetumorigenicityandanti-cancerdrugresponses
    ofcancerstem/initiatingcells
    ProcNatlAcadSciUSA108:12425-12430,2011
    (PubMedID21746895)
  3. KawashimaM,KawakitaT,MaidaY,KamoiM,OgawaY,ShimmuraS,MasutomiK,TsubotaK
    Comparisonoftelomerelengthandassociationwithprogenitorcellmarkersinlacrimal
    glandbetweenSjogrenandnon-Sjogrensyndromedryeyepatients
    MolecularVision17:1397-1404,2011
    (PubMedID21655359)
  4. OkamotoN,YasukawaM,NguyenC,KasimV,MaidaY,PossematoR,ShibataT,LigonKL,FukamiK,HahnWC,MasutomiK
    Maintenanceoftumorinitiatingcellsofdefinedgeneticcompositionbynucleostemin
    ProcNatlAcadSciUSA108:20388-20393,2011
    (PubMedID21730156)
  5. AndoY,MaidaY,MorinagaA,BurroughsAM,KimuraR,ChibaJ,SuzukiH,
    MasutomiK,HayashizakiY
    Two-stepcleavageofhairpinRNAwith5'overhangsbyhumanDICER
    BMCMolecularBiology9;12-6,2011
    (PubMedID21306637)

2009

  1. MaidaY,YasukawaM,FuruuchiM,LassmannT,PossematoR,OkamotoN,
    KasimV,HayashizakiY,HahnWC,MasutomiK
    AnRNAdependentRNApolymeraseformedbyTERTandtheRMRPRNA
    Nature461:230-235,2009
    (PubMedID19701182)

2008

  1. PossematoR,TimmonsJC,BauerleinEL,WadaN,BaldwinA,MasutomiK,HahnWC
    EffectsofInhibitionofPOT1onTelomereLengthandSenescenceinDiploidHumanCells
    MolCancerRes6:1582-1593,2008
    (PubMedID18922974)
  2. ImamuraS,UchiyamaJ,KoshimizuE,HanaiJ,RaftopoulouC,MurpheyRD,
    BaylissPE,ImaiY,BurnsCE,MasutomiK,GagosS,ZonLI,RobertsTM,KishiS
    ANon-CanonicalFunctionofZebrafishTelomeraseReverseTranscriptaseisRequired
    forTheDifferentiationandSurvivalofEmbryonicHematopoieticCells
    PLoSONE3:e3364,2008
    (PubMedID18846223)