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Home > Organization > Divisions and Independent Research Units > Group for Frontier Science > Division of Rare Cancer > Research Projects > Establishment of fundamental research resource of rare cancer: Development of experiment technology

Establishment of fundamental research resource of rare cancer: Development of experiment technology

Rare cancer research has a unique situation: “Number of patients is small, and clinical materials are hardly available for research”. Probably because the clinical materials are not well available for research in rare cancers, the fundamental research tools are not well developed. Division of Rare Cancer Research addresses this issue.

Development of experiment technology The clinical materials for research are generally

limited in number and amount. Especially in rare cancer, this issue influences the research considerably. It is quite important concept to transform the limited research resources such as tumor tissues to the unlimited ones. For this sake, the establishment of patient-derived cancer model is an effective approach. Bioinformatics can also transform the limited resources to the unlimited ones by using “information” which can be replicated and modified unlimitedly. In addition, we developed the proteomics modalities which allow us to investigate the proteome using a very limited amount of tissue samples. Our method enables proteomic study using only 1000-3000 tumor cells, and it has been used by many domestic and oversea researchers. The technology to use a limited amount of clinical samples will be useful not only in the rare cancer studies, but also in all cancer researches.