コンテンツにジャンプ
研究所ロゴ

トップページ > 研究組織一覧 > 基盤的臨床開発研究コアセンター > 機能解析・疾患モデルコア > 細胞培養部門 > 論文業績

論文業績

2017年

  1. Katayama M, Hirayama T, Kiyono T, Onuma M, Tani T, Takeda S, Nishimori K, and Fukuda T: Immortalized prairie vole-derived fibroblasts (VMF-K4DTs) can be transformed into pluripotent stem cells and provide a useful tool with which to determine optimal reprogramming conditions. J Reprod Dev. 2017.
  2. Hashimoto H, Suda Y, Miyashita T, Ochiai A, Tsuboi M, Masutomi K, Kiyono T, and Ishii G: A novel method to generate single-cell-derived cancer-associated fibroblast clones. J Cancer Res Clin Oncol. 2017.
  3. Shinohara M, Sumino Y, Sato F, Kiyono T, Hashimoto N, and Mimata H: Tumor necrosis factor-alpha inhibits differentiation of myogenic cells in human urethral rhabdosphincter. Int J Urol. 2017.

2016年

  1. Yachida S, Wood L D, Suzuki M, Takai E, Totoki Y, Kato M, Luchini C, Arai Y, Nakamura H, Hama N, Elzawahry A, Hosoda F, Shirota T, Morimoto N, Hori K, Funazaki J, Tanaka H, Morizane C, Okusaka T, Nara S, Shimada K, Hiraoka N, Taniguchi H, Higuchi R, Oshima M, Okano K, Hirono S, Mizuma M, Arihiro K, Yamamoto M, Unno M, Yamaue H, Weiss M J, Wolfgang C L, Furukawa T, Nakagama H, Vogelstein B, Kiyono T, Hruban R H, and Shibata T: Genomic Sequencing Identifies ELF3 as a Driver of Ampullary Carcinoma. Cancer cell.29:229-240, 2016.
  2. Tone H, Yoshioka S, Akiyama H, Nishimura A, Ichimura M, Nakatani M, Kiyono T, Toyoda M, Watanabe M, and Umezawa A: Embryoid Body-Explant Outgrowth Cultivation from Induced Pluripotent Stem Cells in an Automated Closed Platform. BioMed research international.2016:7098987, 2016.
  3. Pantic B, Borgia D, Giunco S, Malena A, Kiyono T, Salvatori S, De Rossi A, Giardina E, Sangiuolo F, Pegoraro E, Vergani L, and Botta A: Reliable and versatile immortal muscle cell models from healthy and myotonic dystrophy type 1 primary human myoblasts. Exp Cell Res.342:39-51, 2016.
  4. Katayama M, Kiyono T, Horie K, Hirayama T, Eitsuka T, Kuroda K, Donai K, Hidema S, Nishimori K, and Fukuda T: Establishment of an immortalized cell line derived from the prairie vole via lentivirus-mediated transduction of mutant cyclin-dependent kinase 4, cyclin D, and telomerase reverse transcriptase. Experimental animals / Japanese Association for Laboratory Animal Science.65:87-96, 2016.
  5. Katayama M, Hirayama T, Horie K, Kiyono T, Donai K, Takeda S, Nishimori K, and Fuhttps://www.ncbi.nlm.nih.gov/pubmed/26777120kuda T: Induced Pluripotent Stem Cells With Six Reprogramming Factors From Prairie Vole, Which Is an Animal Model for Social Behaviors. Cell Transplant.25:783-796, 2016.
  6. Kakiuchi T, Takahara T, Kasugai Y, Arita K, Yoshida N, Karube K, Suguro M, Matsuo K, Nakanishi H, Kiyono T, Nakamura S, Osada H, Sekido Y, Seto M, and Tsuzuki S: Modeling mesothelioma utilizing human mesothelial cells reveals involvement of phospholipase-C beta 4 in YAP-active mesothelioma cell proliferation. Carcinogenesis. 2016.
  7. Iwata Y, Suzuki N, Ohtake H, Kamauchi S, Hashimoto N, Kiyono T, and Wakabayashi S: Cancer cachexia causes skeletal muscle damage via transient receptor potential vanilloid 2-independent mechanisms, unlike muscular dystrophy. Journal of cachexia, sarcopenia and muscle.7:366-376, 2016.
  8. Fukuda T, Iino Y, Onuma M, Gen B, Inoue-Murayama M, and Kiyono T: Expression of human cell cycle regulators in the primary cell line of the African savannah elephant (loxodonta africana) increases proliferation until senescence, but does not induce immortalization. In vitro cellular & developmental biology. Animal.52:20-26, 2016.
  9. Fukuda T, Iino Y, Eitsuka T, Onuma M, Katayama M, Murata K, Inoue-Murayama M, Hara K, Isogai E, and Kiyono T: Cellular conservation of endangered midget buffalo (Lowland Anoa, Bubalus quarlesi) by establishment of primary cultured cell, and its immortalization with expression of cell cycle regulators. Cytotechnology.68:1937-1947, 2016.

2015年

  1. Takeshima H, Niwa T, Takahashi T, Wakabayashi M, Yamashita S, Ando T, Inagawa Y, Taniguchi H, Katai H, Sugiyama T, Kiyono T, and Ushijima T: Frequent involvement of chromatin remodeler alterations in gastric field cancerization. Cancer letters.357:328-338, 2015.
  2. Nakamura T, Iwase A, Bayasula B, Nagatomo Y, Kondo M, Nakahara T, Takikawa S, Goto M, Kotani T, Kiyono T, and Kikkawa F: CYP51A1 induced by growth differentiation factor 9 and follicle-stimulating hormone in granulosa cells is a possible predictor for unfertilization. Reprod Sci.22:377-384, 2015.
  3. Kuroda K, Kiyono T, Isogai E, Masuda M, Narita M, Okuno K, Koyanagi Y, and Fukuda T: Immortalization of Fetal Bovine Colon Epithelial Cells by Expression of Human Cyclin D1, Mutant Cyclin Dependent Kinase 4, and Telomerase Reverse Transcriptase: An In Vitro Model for Bacterial Infection. PloS one.10:e0143473, 2015.
  4. Kuroda K, Kiyono T, Eitsuka T, Isogai H, Takahashi K, Donai K, Isogai E, and Fukuda T: Establishment of cell lines derived from the genus Macaca through controlled expression of cell cycle regulators. Journal of cellular biochemistry.116:205-211, 2015.

2014年

  1. Fuchigami T, Kibe T, Koyama H, Kishida S, Iijima M, Nishizawa Y, Hijioka H, Fujii T, Ueda M, Nakamura N, Kiyono T, and Kishida M: Regulation of IL-6 and IL-8 production by reciprocal cell-to-cell interactions between tumor cells and stromal fibroblasts through IL-1alpha in ameloblastoma. Biochem Biophys Res Commun.451:491-496, 2014.
  2. Donai K, Kiyono T, Eitsuka T, Guo Y, Kuroda K, Sone H, Isogai E, and Fukuda T: Bovine and porcine fibroblasts can be immortalized with intact karyotype by the expression of mutant cyclin dependent kinase 4, cyclin D, and telomerase. Journal of biotechnology.176:50-57, 2014.
  3. Chihara D, Kagami Y, Kato H, Yoshida N, Kiyono T, Okada Y, Kinoshita T, and Seto M: IL2/IL-4, OX40L and FDC-like cell line support the in vitro tumor cell growth of adult T-cell leukemia/lymphoma. Leukemia research.38:608-612, 2014.
  4. Inagawa Y, Yamada K, Yugawa T, Ohno S, Hiraoka N, Esaki M, Shibata T, Aoki K, Saya H, and Kiyono T: A human cancer xenograft model utilizing normal pancreatic duct epithelial cells conditionally transformed with defined oncogenes. Carcinogenesis.35:1840-1846, 2014.
  5. Shiomi K, Nagata Y, Kiyono T, Harada A, and Hashimoto N: Differential impact of the bisphosphonate alendronate on undifferentiated and terminally differentiated human myogenic cells. The Journal of pharmacy and pharmacology.66:418-427, 2014.