コンテンツにジャンプ
研究所ロゴ

トップページ > 研究組織一覧 > 分野・独立ユニットグループ > 分子標的研究グループ > 造血器腫瘍研究分野 > 論文業績

論文業績

2017年 

  1. Nakagawa M, Nakatani F, Kitabayashi I. [I. Identification of a Possible Therapeutic Target for Chondrosarcoma with IDH Mutant Inhibitors]. Gan To Kagaku Ryoho. 2017 Mar;44(3):212-216. Japanese. PubMed PMID: 28400543.
  2. Shima Y, Yumoto M, Katsumoto T, Kitabayashi I. MLL is essential for N UP98-HOXA9-induced leukemia. Leukemia. 2017 Mar 10. doi: 10.1038/leu.2017.62. [Epub ahead of print] PubMed PMID: 28210005.
  3. Takamatsu-Ichihara E, Kitabayashi I. The roles of Polycomb group proteins in hematopoietic stem cells and hematological malignancies. Int J Hematol. 2016 Jun;103(6):634-42. doi: 10.1007/s12185-016-2011-5. Epub 2016 Apr 16. Review. PubMed PMID: 27086351.
  4. Tabu K, Muramatsu N, Mangani C, Wu M, Zhang R, Kimura T, Terashima K, Bizen N, Kimura R, Wang W, Murota Y, Kokubu Y, Nobuhisa I, Kagawa T, Kitabayashi I, Bradley M, Taga T. A Synthetic Polymer Scaffold Reveals the Self-Maintenance Strategies of Rat Glioma Stem Cells by Organization of the Advantageous Niche. Stem Cells. 2016 May;34(5):1151-62. doi: 10.1002/stem.2299. Epub 2016 Feb 19. PubMed PMID: 26822103.
  5. Asano Y, Kawase T, Okabe A, Tsutsumi S, Ichikawa H, Tatebe S, Kitabayashi I, Tashiro F, Namiki H, Kondo T, Semba K, Aburatani H, Taya Y, Nakagama H, Ohki R. IER5 generates a novel hypo-phosphorylated active form of HSF1 and contributes to tumorigenesis. Sci Rep. 2016 Jan 12;6:19174. doi: 10.1038/srep19174. PubMed PMID: 26754925; PubMed Central PMCID: PMC4709660.
  6. Ogawara Y, Kitabayashi I. [IDH mutations activate Hoxa9/Meis1 and hypoxia pathways in acute myeloid leukemia model mice]. Rinsho Ketsueki. 2015 Aug;56(8):1045-52. doi: 10.11406/rinketsu.56.1045. Japanese. PubMed PMID: 26345565.
  7. Ogawara Y, Katsumoto T, Aikawa Y, Shima Y, Kagiyama Y, Soga T, Matsunaga H, Seki T, Araki K, Kitabayashi I. IDH2 and NPM1 Mutations Cooperate to Activate Hoxa9/Meis1 and Hypoxia Pathways in Acute Myeloid Leukemia. Cancer Res. 2015 May 15;75(10):2005-16. doi: 10.1158/0008-5472.CAN-14-2200. Epub 2015 Mar 20. PubMed PMID: 25795706.
  8. Aikawa Y, Yamagata K, Katsumoto T, Shima Y, Shino M, Stanley ER, Cleary ML, Akashi K, Tenen DG, Kitabayashi I. Essential role of PU.1 in maintenance of mixed lineage leukemia-associated leukemic stem cells. Cancer Sci. 2015 Mar;106(3):227-36. doi: 10.1111/cas.12593. Epub 2015 Feb 12. PubMed PMID: 25529853; PubMed Central PMCID: PMC4373983.
  9. Nakamoto-Matsubara R, Sakata-Yanagimoto M, Enami T, Yoshida K, Yanagimoto S, Shiozawa Y, Nanmoku T, Satomi K, Muto H, Obara N, Kato T, Kurita N, Yokoyama Y, Izutsu K, Ota Y, Sanada M, Shimizu S, Komeno T, Sato Y, Ito T, Kitabayashi I, Takeuchi K, Nakamura N, Ogawa S, Chiba S. Detection of the G17V RHOA mutation in angioimmunoblastic T-cell lymphoma and related lymphomas using quantitative allele-specific PCR. PLoS One. 2014 Oct 13;9(10):e109714. doi: 10.1371/journal.pone.0109714. eCollection 2014. PubMed PMID: 25310466; PubMed Central PMCID: PMC4195681.
  10. Kato T, Sakata-Yanagimoto M, Nishikii H, Ueno M, Miyake Y, Yokoyama Y, Asabe Y, Kamada Y, Muto H, Obara N, Suzukawa K, Hasegawa Y, Kitabayashi I, Uchida K, Hirao A, Yagita H, Kageyama R, Chiba S. Hes1 suppresses acute myeloid leukemia development through FLT3 repression. Leukemia. 2015 Mar;29(3):576-85. doi: 10.1038/leu.2014.281. Epub 2014 Sep 19. PubMed PMID: 25234168.
  11. Nakahata S, Ichikawa T, Maneesaay P, Saito Y, Nagai K, Tamura T, Manachai N, Yamakawa N, Hamasaki M, Kitabayashi I, Arai Y, Kanai Y, Taki T, Abe T, Kiyonari H, Shimoda K, Ohshima K, Horii A, Shima H, Taniwaki M, Yamaguchi R, Morishita K. Loss of NDRG2 expression activates PI3K-AKT signalling via PTEN phosphorylation in ATLL and other cancers. Nat Commun. 2014 Feb 26;5:3393. doi: 10.1038/ncomms4393. PubMed PMID: 24569712; PubMed Central PMCID: PMC3948061.
  12. Miyagi S, Koide S, Saraya A, Wendt GR, Oshima M, Konuma T, Yamazaki S, Mochizuki-Kashio M, Nakajima-Takagi Y, Wang C, Chiba T, Kitabayashi I, Nakauchi H, Iwama A. The TIF1β-HP1 system maintains transcriptional integrity of hematopoietic stem cells. Stem Cell Reports. 2014 Jan 23;2(2):145-52. doi: 10.1016/j.stemcr.2013.12.008. eCollection 2014 Feb 11. PubMed PMID: 24527388; PubMed Central PMCID: PMC3923190.
  13. Okuda H, Kawaguchi M, Kanai A, Matsui H, Kawamura T, Inaba T, Kitabayashi I, Yokoyama A. MLL fusion proteins link transcriptional coactivators to previously active CpG-rich promoters. Nucleic Acids Res. 2014 Apr;42(7):4241-56. doi: 10.1093/nar/gkt1394. Epub 2014 Jan 23. PubMed PMID: 24465000; PubMed Central PMCID: PMC3985622.
  14. Suzuki M, Yamagata K, Shino M, Aikawa Y, Akashi K, Watanabe T, Kitabayashi I. Nuclear export signal within CALM is necessary for CALM-AF10-induced leukemia. Cancer Sci. 2014 Mar;105(3):315-23. doi: 10.1111/cas.12347. Epub 2014 Feb 13. PubMed PMID: 24397609; PubMed Central PMCID: PMC4317939.
  15. Iwamoto C, Takenaka K, Urata S, Yamauchi T, Shima T, Kuriyama T, Daitoku S, Saito Y, Miyamoto T, Iwasaki H, Kitabayashi I, Itoh K, Kishimoto J, Kohda D, Matozaki T, Akashi K. The BALB/c-specific polymorphic SIRPA enhances its affinity for human CD47, inhibiting phagocytosis against human cells to promote xenogeneic engraftment. Exp Hematol. 2014 Mar;42(3):163-171.e1. doi: 10.1016/j.exphem.2013.11.005. Epub 2013 Nov 20. PubMed PMID: 24269920.
  16. Shima H, Yamagata K, Aikawa Y, Shino M, Koseki H, Shimada H, Kitabayashi I. Bromodomain-PHD finger protein 1 is critical for leukemogenesis associated with MOZ-TIF2 fusion. Int J Hematol. 2014 Jan;99(1):21-31. doi: 10.1007/s12185-013-1466-x. Epub 2013 Nov 21. PubMed PMID: 24258712.
  17. Yokoyama A, Ficara F, Murphy MJ, Meisel C, Hatanaka C, Kitabayashi I, Cleary ML. MLL becomes functional through intra-molecular interaction not by proteolytic processing. PLoS One. 2013 Sep 10;8(9):e73649. doi: 10.1371/journal.pone.0073649. eCollection 2013. PubMed PMID: 24040009; PubMed Central PMCID: PMC3769346.
  18. Shima Y, Honma Y, Kitabayashi I. PML-RARα and its phosphorylation regulate pml oligomerization and HIPK2 stability. Cancer Res. 2013 Jul 15;73(14):4278-88. doi: 10.1158/0008-5472.CAN-12-3814. Epub 2013 May 30. PubMed PMID: 23722549.
  19. Shimizu K, Yamagata K, Kurokawa M, Mizutani S, Tsunematsu Y, Kitabayashi I. Roles of AML1/RUNX1 in T-cell malignancy induced by loss of p53. Cancer Sci. 2013 Aug;104(8):1033-8. doi: 10.1111/cas.12199. Epub 2013 Jun 20. PubMed PMID: 23679839.
  20. Haga A, Ogawara Y, Kubota D, Kitabayashi I, Murakami Y, Kondo T. Interactomic approach for evaluating nucleophosmin-binding proteins as biomarkers for Ewing's sarcoma. Electrophoresis. 2013 Jun;34(11):1670-8. doi: 10.1002/elps.201200661. PubMed PMID: 23483572.
  21. Iwanami A, Gini B, Zanca C, Matsutani T, Assuncao A, Nael A, Dang J, Yang H, Zhu S, Kohyama J, Kitabayashi I, Cavenee WK, Cloughesy TF, Furnari FB, Nakamura M, Toyama Y, Okano H, Mischel PS. PML mediates glioblastoma resistance to mammalian target of rapamycin (mTOR)-targeted therapies. Proc Natl Acad Sci U S A. 2013 Mar 12;110(11):4339-44. doi: 10.1073/pnas.1217602110. Epub 2013 Feb 25. PubMed PMID: 23440206; PubMed Central PMCID: PMC3600508.
  22. Rokudai S, Laptenko O, Arnal SM, Taya Y, Kitabayashi I, Prives C. MOZ increases p53 acetylation and premature senescence through its complex formation with PML. Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):3895-900. doi: 10.1073/pnas.1300490110. Epub 2013 Feb 19. PubMed PMID: 23431171; PubMed Central PMCID: PMC3593914.
  23. Katsumoto T, Kitabayashi I. [Transcriptional regulation]. Nihon Rinsho. 2012 Apr;70 Suppl 2:75-8. Japanese. PubMed PMID: 23133931.
  24. Satow R, Shitashige M, Jigami T, Fukami K, Honda K, Kitabayashi I, Yamada T. β-catenin inhibits promyelocytic leukemia protein tumor suppressor function in colorectal cancer cells. Gastroenterology. 2012 Mar;142(3):572-81. doi: 10.1053/j.gastro.2011.11.041. Epub 2011 Dec 9. PubMed PMID: 22155184.
  25. Shima Y, Kitabayashi I. Deregulated transcription factors in leukemia. Int J Hematol. 2011 Aug;94(2):134-41. doi: 10.1007/s12185-011-0905-9. Epub 2011 Aug 9. Review. PubMed PMID: 21823042.
  26. Mishima Y, Miyagi S, Saraya A, Negishi M, Endoh M, Endo TA, Toyoda T, Shinga J, Katsumoto T, Chiba T, Yamaguchi N, Kitabayashi I, Koseki H, Iwama A. The Hbo1-Brd1/Brpf2 complex is responsible for global acetylation of H3K14 and required for fetal liver erythropoiesis. Blood. 2011 Sep 1;118(9):2443-53. doi: 10.1182/blood-2011-01-331892. Epub 2011 Jul 13. PubMed PMID: 21753189.
  27. Yokoyama A, Ficara F, Murphy MJ, Meisel C, Naresh A, Kitabayashi I, Cleary ML. Proteolytically cleaved MLL subunits are susceptible to distinct degradation pathways. J Cell Sci. 2011 Jul 1;124(Pt 13):2208-19. doi: 10.1242/jcs.080523. PubMed PMID: 21670200; PubMed Central PMCID: PMC3113671.
  28. Ozeki C, Sawai Y, Shibata T, Kohno T, Okamoto K, Yokota J, Tashiro F, Tanuma S, Sakai R, Kawase T, Kitabayashi I, Taya Y, Ohki R. Cancer susceptibility polymorphism of p53 at codon 72 affects phosphorylation and degradation of p53 protein. J Biol Chem. 2011 May 20;286(20):18251-60. doi: 10.1074/jbc.M110.208587. Epub 2011 Mar 28. PubMed PMID: 21454683; PubMed Central PMCID: PMC3093897.
  29. Aikawa Y, Katsumoto T, Zhang P, Shima H, Shino M, Terui K, Ito E, Ohno H, Stanley ER, Singh H, Tenen DG, Kitabayashi I. PU.1-mediated upregulation of CSF1R is crucial for leukemia stem cell potential induced by MOZ-TIF2. Nat Med. 2010 May;16(5):580-5, 1p following 585. doi: 10.1038/nm.2122. Epub 2010 Apr 25. PubMed PMID: 20418886; PubMed Central PMCID: PMC3039870.
  30. Yokoyama A, Lin M, Naresh A, Kitabayashi I, Cleary ML. A higher-order complex containing AF4 and ENL family proteins with P-TEFb facilitates oncogenic and physiologic MLL-dependent transcription. Cancer Cell. 2010 Feb 17;17(2):198-212. doi: 10.1016/j.ccr.2009.12.040. PubMed PMID: 20153263; PubMed Central PMCID: PMC2824033.
  31. Yamagata K, Kitabayashi I. Sirt1 physically interacts with Tip60 and negatively regulates Tip60-mediated acetylation of H2AX. Biochem Biophys Res Commun. 2009 Dec 25;390(4):1355-60. doi: 10.1016/j.bbrc.2009.10.156. Epub 2009 Nov 4. PubMed PMID: 19895790.
  32. Kitoh A, Ono M, Naoe Y, Ohkura N, Yamaguchi T, Yaguchi H, Kitabayashi I, Tsukada T, Nomura T, Miyachi Y, Taniuchi I, Sakaguchi S. Indispensable role of the Runx1-Cbfbeta transcription complex for in vivo-suppressive function of FoxP3+ regulatory T cells. Immunity. 2009 Oct 16;31(4):609-20. doi: 10.1016/j.immuni.2009.09.003. Epub 2009 Oct 1. PubMed PMID: 19800266.
  33. Hibiya K, Katsumoto T, Kondo T, Kitabayashi I, Kudo A. Brpf1, a subunit of the MOZ histone acetyl transferase complex, maintains expression of anterior and posterior Hox genes for proper patterning of craniofacial and caudal skeletons. Dev Biol. 2009 May 15;329(2):176-90. doi: 10.1016/j.ydbio.2009.02.021. Epub 2009 Feb 27. PubMed PMID: 19254709.
  34. Rokudai S, Aikawa Y, Tagata Y, Tsuchida N, Taya Y, Kitabayashi I. Monocytic leukemia zinc finger (MOZ) interacts with p53 to induce p21 expression and cell-cycle arrest. J Biol Chem. 2009 Jan 2;284(1):237-44. doi: 10.1074/jbc.M805101200. Epub 2008 Nov 10. PubMed PMID: 19001415.
  35. Shima Y, Shima T, Chiba T, Irimura T, Pandolfi PP, Kitabayashi I. PML activates transcription by protecting HIPK2 and p300 from SCFFbx3-mediated degradation. Mol Cell Biol. 2008 Dec;28(23):7126-38. doi: 10.1128/MCB.00897-08. Epub 2008 Sep 22. PubMed PMID: 18809579; PubMed Central PMCID: PMC2593379.
  36. Katsumoto T, Yoshida N, Kitabayashi I. Roles of the histone acetyltransferase monocytic leukemia zinc finger protein in normal and malignant hematopoiesis. Cancer Sci. 2008 Aug;99(8):1523-7. doi: 10.1111/j.1349-7006.2008.00865.x. Review. PubMed PMID: 18754862.
  37. Hayakawa F, Abe A, Kitabayashi I, Pandolfi PP, Naoe T. Acetylation of PML is involved in histone deacetylase inhibitor-mediated apoptosis. J Biol Chem. 2008 Sep 5;283(36):24420-5. doi: 10.1074/jbc.M802217200. Epub 2008 Jul 11. PubMed PMID: 18621739; PubMed Central PMCID: PMC3259823.
  38. Marshall LJ, Moore AC, Ohki M, Kitabayashi I, Patterson D, Ornelles DA. RUNX1 permits E4orf6-directed nuclear localization of the adenovirus E1B-55K protein and associates with centers of viral DNA and RNA synthesis. J Virol. 2008 Jul;82(13):6395-408. doi: 10.1128/JVI.00043-08. Epub 2008 Apr 16. PubMed PMID: 18417565; PubMed Central PMCID: PMC2447068.
  39. Tachibana M, Tezuka C, Muroi S, Nishimoto S, Katsumoto T, Nakajima A, Kitabayashi I, Taniuchi I. Phosphorylation of Runx1 at Ser249, Ser266, and Ser276 is dispensable for bone marrow hematopoiesis and thymocyte differentiation. Biochem Biophys Res Commun. 2008 Apr 11;368(3):536-42. doi: 10.1016/j.bbrc.2008.01.124. Epub 2008 Feb 6. PubMed PMID: 18261462.
  40. Yoshida H, Kitabayashi I. Chromatin regulation by AML1 complex. Int J Hematol. 2008 Jan;87(1):19-24. doi: 10.1007/s12185-007-0004-0. Epub 2007 Nov 27. PubMed PMID: 18224409.
  41. Sugimoto N, Kitabayashi I, Osano S, Tatsumi Y, Yugawa T, Narisawa-Saito M, Matsukage A, Kiyono T, Fujita M. Identification of novel human Cdt1-binding proteins by a proteomics approach: proteolytic regulation by APC/CCdh1. Mol Biol Cell. 2008 Mar;19(3):1007-21. Epub 2007 Dec 27. PubMed PMID: 18162579; PubMed Central PMCID: PMC2262995.
  42. Tagata Y, Yoshida H, Nguyen LA, Kato H, Ichikawa H, Tashiro F, Kitabayashi I. Phosphorylation of PML is essential for activation of C/EBP epsilon and PU.1 to accelerate granulocytic differentiation. Leukemia. 2008 Feb;22(2):273-80. Epub 2007 Nov 8. PubMed PMID: 17989716.
  43. Yoshida H, Ichikawa H, Tagata Y, Katsumoto T, Ohnishi K, Akao Y, Naoe T, Pandolfi PP, Kitabayashi I. PML-retinoic acid receptor alpha inhibits PML IV enhancement of PU.1-induced C/EBPepsilon expression in myeloid differentiation. Mol Cell Biol. 2007 Aug;27(16):5819-34. Epub 2007 Jun 11. PubMed PMID: 17562868; PubMed Central PMCID: PMC1952121.
  44. Li XL, Arai Y, Harada H, Shima Y, Yoshida H, Rokudai S, Aikawa Y, Kimura A, Kitabayashi I. Mutations of the HIPK2 gene in acute myeloid leukemia and myelodysplastic syndrome impair AML1- and p53-mediated transcription. Oncogene. 2007 Nov 8;26(51):7231-9. Epub 2007 May 28. PubMed PMID: 17533375.
  45. Kitabayashi I. [Transcription regulation and leukemia]. Nihon Rinsho. 2007 Jan 28;65 Suppl 1:41-5. Review. Japanese. PubMed PMID: 17474393.
  46. Ono M, Yaguchi H, Ohkura N, Kitabayashi I, Nagamura Y, Nomura T, Miyachi Y, Tsukada T, Sakaguchi S. Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1. Nature. 2007 Apr 5;446(7136):685-9. Epub 2007 Mar 21. PubMed PMID: 17377532.
  47. Nakamura Y, Yamagata T, Maki K, Sasaki K, Kitabayashi I, Mitani K. 電話番号/ETV6 binds to corepressor KAP1 via the HLH domain. Int J Hematol. 2006 Nov;84(4):377-80. PubMed PMID: 17118767.
  48. Okamoto K, Kitabayashi I, Taya Y. KAP1 dictates p53 response induced by chemotherapeutic agents via Mdm2 interaction. Biochem Biophys Res Commun. 2006 Dec 8;351(1):216-22. Epub 2006 Oct 12. PubMed PMID: 17056014.
  49. Aikawa Y, Nguyen LA, Isono K, Takakura N, Tagata Y, Schmitz ML, Koseki H, Kitabayashi I. Roles of HIPK1 and HIPK2 in AML1- and p300-dependent transcription, hematopoiesis and blood vessel formation. EMBO J. 2006 Sep 6;25(17):3955-65. Epub 2006 Aug 17. PubMed PMID: 16917507; PubMed Central PMCID: PMC1560355.
  50. Katsumoto T, Aikawa Y, Iwama A, Ueda S, Ichikawa H, Ochiya T, Kitabayashi I. MOZ is essential for maintenance of hematopoietic stem cells. Genes Dev. 2006 May 15;20(10):1321-30. PubMed PMID: 16702405; PubMed Central PMCID: PMC1472906.
  51. Xu G, Kanezaki R, Toki T, Watanabe S, Takahashi Y, Terui K, Kitabayashi I, Ito E. Physical association of the patient-specific GATA1 mutants with RUNX1 in acute megakaryoblastic leukemia accompanying Down syndrome. Leukemia. 2006 Jun;20(6):1002-8. PubMed PMID: 16628190.
  52. Enari M, Ohmori K, Kitabayashi I, Taya Y. Requirement of clathrin heavy chain for p53-mediated transcription. Genes Dev. 2006 May 1;20(9):1087-99. Epub 2006 Apr 17. PubMed PMID: 16618797; PubMed Central PMCID: PMC1472469.
  53. Okamoto K, Kashima K, Pereg Y, Ishida M, Yamazaki S, Nota A, Teunisse A, Migliorini D, Kitabayashi I, Marine JC, Prives C, Shiloh Y, Jochemsen AG, Taya Y. DNA damage-induced phosphorylation of MdmX at serine 367 activates p53 by targeting MdmX for Mdm2-dependent degradation. Mol Cell Biol. 2005 Nov;25(21):9608-20. PubMed PMID: 16227609; PubMed Central PMCID: PMC1265801.
  54. Kishimoto M, Kohno T, Okudela K, Otsuka A, Sasaki H, Tanabe C, Sakiyama T, Hirama C, Kitabayashi I, Minna JD, Takenoshita S, Yokota J. Mutations and deletions of the CBP gene in human lung cancer. Clin Cancer Res. 2005 Jan 15;11(2Pt 1):512-9. PubMed PMID: 15701835.
  55. Nguyen LA, Pandolfi PP, Aikawa Y, Tagata Y, Ohki M, Kitabayashi I. Physical and functional link of the leukemia-associated factors AML1 and PML. Blood. 2005 Jan 1;105(1):292-300. Epub 2004 Aug 26. PubMed PMID: 15331439.
  56. Yaguchi H, Ohkura N, Takahashi M, Nagamura Y, Kitabayashi I, Tsukada T. Menin missense mutants associated with multiple endocrine neoplasia type 1 are rapidly degraded via the ubiquitin-proteasome pathway. Mol Cell Biol. 2004 Aug;24(15):6569-80. PubMed PMID: 15254225; PubMed Central PMCID: PMC444842.
  57. Yokoyama A, Wang Z, Wysocka J, Sanyal M, Aufiero DJ, Kitabayashi I, Herr W, Cleary ML. Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression. Mol Cell Biol. 2004 Jul;24(13):5639-49. PubMed PMID: 15199122; PubMed Central PMCID: PMC480881.
  58. Yasuda J, Yokoo H, Yamada T, Kitabayashi I, Sekiya T, Ichikawa H. Nemo-like kinase suppresses a wide range of transcription factors, including nuclear factor-kappaB. Cancer Sci. 2004 Jan;95(1):52-7. PubMed PMID: 14720327.
  59. Imamura T, Kakazu N, Hibi S, Morimoto A, Fukushima Y, Ijuin I, Hada S, Kitabayashi I, Abe T, Imashuku S. Rearrangement of the MOZ gene in pediatric therapy-related myelodysplastic syndrome with a novel chromosomal translocation t(2;8)(p23;p11). Genes Chromosomes Cancer. 2003 Apr;36(4):413-9. PubMed PMID: 12619166.
  60. Yokoyama A, Kitabayashi I, Ayton PM, Cleary ML, Ohki M. Leukemia proto-oncoprotein MLL is proteolytically processed into 2 fragments with opposite transcriptional properties. Blood. 2002 Nov 15;100(10):3710-8. Epub 2002 Jun 28. PubMed PMID: 12393701.
  61. Suhara W, Yoneyama M, Kitabayashi I, Fujita T. Direct involvement of CREB-binding protein/p300 in sequence-specific DNA binding of virus-activated interferon regulatory factor-3 holocomplex. J Biol Chem. 2002 Jun 21;277(25):22304-13. Epub 2002 Apr 8. PubMed PMID: 11940575.
  62. Kitabayashi I, Aikawa Y, Nguyen LA, Yokoyama A, Ohki M. Activation of AML1-mediated transcription by MOZ and inhibition by the MOZ-CBP fusion protein. EMBO J. 2001 Dec 17;20(24):7184-96. PubMed PMID: 11742995; PubMed Central PMCID: PMC125775.
  63. Yokoyama A, Tanaka M, Matsuda G, Kato K, Kanamori M, Kawasaki H, Hirano H, Kitabayashi I, Ohki M, Hirai K, Kawaguchi Y. Identification of major phosphorylation sites of Epstein-Barr virus nuclear antigen leader protein (EBNA-LP): ability of EBNA-LP to induce latent membrane protein 1 cooperatively with EBNA-2 is regulated by phosphorylation. J Virol. 2001 Jun;75(11):5119-28. PubMed PMID: 11333893; PubMed Central PMCID: PMC114917.
  64. Kitabayashi I, Aikawa Y, Yokoyama A, Hosoda F, Nagai M, Kakazu N, Abe T, Ohki M. Fusion of MOZ and p300 histone acetyltransferases in acute monocytic leukemia with a t(8;22)(p11;q13) chromosome translocation. Leukemia. 2001 Jan;15(1):89-94. PubMed PMID: 11243405.
  65. Yokoyama A, Kawaguchi Y, Kitabayashi I, Ohki M, Hirai K. The conserved domain CR2 of Epstein-Barr virus nuclear antigen leader protein is responsible not only for nuclear matrix association but also for nuclear localization. Virology. 2001 Jan 20;279(2):401-13. PubMed PMID: 11162796.