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Home > Hiroaki Ikematsu, MD, PhD

Hiroaki Ikematsu, MD, PhD

The strongest advantage of gastrointestinal endoscopy is early detection and early treatment of gastrointestinal cancer. Therefore, I would like to work with the company and academia to develop new endoscope equipment using the latest technologies such as new imaging endoscope and artificial intelligence (AI).

Official Title

  • Division of Science and Technology for Endoscopy
  • Department of Gastroenterology and Endoscopy

Area of reserch

  • Gastrointestinal endoscopy 
  • Colorectal cancer 
  • Colonoscopic diagnosis 
  • Colonoscopic treatment


  • Image-enhanced endoscopy 
  • Detection 
  • ESD 
  • Near infrared light

Current main research theme

  • Equipment development of endoscopic diagnosis, treatment and prevention

Collaborative research themes

  • Endoscopic imaging 
  • Equipment development of endoscopic diagnosis, treatment and prevention


hikemats●east.ncc.go.jp(● replace to @)

Brief history

  • 1992-1998 National Defense Medical College, Japan
  • 2009-2013 Graduate School of Medicine, Dokkyo Medical University 
  • 2006-2015 Department of Gastroenterology and Endoscopy, National Cancer Center Hospital East, Staff 
  • 2015-present Department of Gastroenterology and Endoscopy, National Cancer Center Hospital East, Head 
  • 2017-present Division of Science and Technology for Endoscopy, National Cancer Center Chief

Major affiliated societies

  • American Society for Gastrointestinal Endoscopy 
  • The Japan Gastroenterological Endoscopy Society 
  • The Japanese Society of Gastroenterology 
  • The Japanese Gastroenterological Association 
  • The Japanese Society of Internal Medicine 
  • The Japan Society of Colon Examination 
  • American Society for Gastrointestinal Endoscopy


  1. Ikematsu H, Sakamoto T, Togashi K, Yoshida N, Hisabe T, Kiriyama S, Matsuda K, Hayashi Y, Matsuda T, Osera S, Kaneko K, Utano K, Naito Y, Ishihara H, Kato M, Yoshimura K, Ishikawa H, Yamamoto H, Saito Y. Detectability of colorectal neoplastic lesions using a novel endoscopic system with blue laser imaging: a multicenter randomized controlled trial. Gastrointest Endosc. 2017 in press 
  2. Sano Y, Tanaka S, Kudo SE, Saito S, Matsuda T, Wada Y, Fujii T, Ikematsu H, Uraoka T, Kobayashi N, Nakamura H, Hotta K, Horimatsu T, Sakamoto N, Fu KI, Tsuruta O, Kawano H, Kashida H, Takeuchi Y, Machida H, Kusaka T, Yoshida N, Hirata I, Terai T, Yamano HO, Kaneko K, Nakajima T, Sakamoto T, Yamaguchi Y, Tamai N, Nakano N, Hayashi N, Oka S, Iwatate M, Ishikawa H, Murakami Y, Yoshida S, Saito Y. Narrow-band imaging (NBI) magnifying endoscopic classification of colorectal tumors proposed by the Japan NBI Expert Team. Dig Endosc. 2016;28:526-33. 
  3. Osera S, Fujii S, Ikematsu H, Miyamoto H, Oono Y, Yano T, Ochiai A, Yoshino T, Ohtsu A, Kaneko K. Clinicopathological, endoscopic, and molecular characteristics of the "skirt" - a new entity of lesions at the margin of laterally spreading tumors. Endoscopy. 2016;48:448-55. 
  4. Ikematsu H, Matsuda T, Osera S, Imajoh M, Kadota T, Morimoto H, Sakamoto T, Oono Y, Kaneko K, Saito Y. Usefulness of narrow-band imaging with dual-focus magnification for differential diagnosis of small colorectal polyps. Surg Endosc. 2015;29:844-50. 
  5. Kaneko K, Yamaguchi H, Saito T, Yano T, Oono Y, Ikematsu H, Nomura S, Sato A, Kojima M, Esumi H, Ochiai A. Hypoxia imaging endoscopy equipped with laser light source from preclinical live animal study to first-in-human subject research. PLoS One. 2014;10;9:e99055. 
  6. Yoda Y, Ikematsu H, Matsuda T, Yamaguchi Y, Hotta K, Kobayashi N, Fujii T, Oono Y, Sakamoto T, Nakajima T, Takao M, Shinohara T, Fujimori T, Kaneko K, Saito Y. A large-scale multicenter study of long-term outcomes after endoscopic resection for submucosal invasive colorectal cancer. Endoscopy. 2013;45:718-24. 
  7. Ikematsu H, Yoda Y, Matsuda T, Yamaguchi, Y, Hotta K, Kobayashi N, Fujii T, Oono Y, Sakamoto T, Nakajima T, Takao M, Shinohara T, Murakami Y, Fujimori T, Kaneko K, Saito Y. Long-Term Outcomes after Resection for Submucosal Invasive Colorectal Cancers. Gastroenterology. 2013;144:551-9. 
  8. Ikematsu H, Saito Y, Tanaka S, Uraoka T, Sano Y, Horimatsu T, Matsuda T, Oka S, Higashi R, Ishikawa H, Kaneko K. The impact of narrow band imaging for colon polyp detection: a multicenter randomized controlled trial by tandem colonoscopy. J Gastroenterol. 2012;47:1099-107 
  9. Saraya T, Ikematsu H, Fu KI, Tsunoda C, Yoda Y, Oono Y, Kojima T, Yano T, Horimatsu T, Sano Y, Kaneko K. Evaluation of complications related to therapeutic colonoscopy using the bipolar snare. Surg Endosc. 2012;26:533-40 
  10. Saito Y, Uraoka T, Yamaguchi Y, Hotta K, Sakamoto N, Ikematsu H, Fukuzawa M, Kobayashi N, Nasu J, Michida T, Yoshida S, Ikehara H, Otake Y, Nakajima T, Matsuda T, Saito D. A prospective, multicenter study of 1111 colorectal endoscopic submucosal dissections (with video). Gastrointest Endosc. 2010;72:1217-25 
  11. Ikematsu H, Matsuda T, Emura F, Saito Y, Uraoka T, Fu KI, Kaneko K, Ochiai A, Fujimori T, Sano Y. Efficacy of capillary pattern type IIIA/IIIB by magnifying narrow band imaging for estimating depth of invasion of early colorectal neoplasms. BMC Gastroenterol. 2010;10:33