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HOME > Publication & Reports > Annual Report 2016 > Research Center for Cancer Prevention and Screening

Division of Health Care Research

Yutaka Matsuoka, Yosuke Uchitomi, Yasuhito Uezono, Eriko Satomi, Ken Shimizu, Masashi Kato, Sadamoto Zenda, Takuhiro Yamaguchi, Miki Kawahara, Tempei Miyaji, Chikako Kusano, Kyoko Akutsu, Yumi Kikukawa, Koji Washizuka, Ayako Sato, You-ichi Shimizu, Masanori Mori, Maiko Fujimori


The Division of Health Care Research was established in January 2016. Our division focuses on behavioral and health care delivery research in cancer survivorship to enhance the quality of survival for all people diagnosed with cancer along with their family caregivers. Our division initiates interdisciplinary research programs ranging from basic bio-behavioral science to development, testing, and delivery of behavioral interventions in areas such as nutrition, physical activity, health communication, nursing, and mental health. Our division also manages the J-SUPPORT [Japan Supportive, Palliative and Psychosocial Oncology Group] as a central support office.

Our team and what we do

1.Bio-behavioral health research team

To enhance the quality of survival for all people diagnosed with cancer and to minimize or stabilize depression and anxiety experienced during cancer survivorship, we focus on diet, nutrition, and physical activity.

2.Communication and care delivery research team

To promote communication and decision-making process based on patients'values and preference between patients, caregivers, and physicians, we are conducting experimental psychological studies and clinical trials.

3.Family nursing and psychosocial support research team

To improve the quality of life for bereaved families of cancer patients, we focus on their satisfaction through care during hospitalization and resilience as a modifiable factor.

4.QOL outcome research team

To enhance the quality of J-SUPPORT endorsed trials, we provide design consultation, data management, monitoring, and statistical analysis. We tackle the selection of clinical outcome assessments through systematic reviews.

Research activities

1)We reported that post-trauma supplementation of omega-3 fatty acid might be effective for secondary prevention for psychophysiological symptoms of posttraumatic stress disorder; the frequency of fried food consumption was associated with lower resilience to depression; exercise might be associated with depression thorough social support and resilience. We finished the recruitment of participants for prospective cohort study of acute coronary syndrome.

2)We conducted an experimental study to investigate the favorable patient-physician communication regarding cancer diagnosis and finished the recruitment.

3)We wrote two study protocols. The first one, which is regarding resilience was approved by Tohoku University and St. Luke's International Hospital. The second one, which is regarding satisfaction with care was approved by the Shizuoka Cancer Center. Both of the two projects launched their investigations.

4)We conducted systematic reviews on the selection of clinical outcome assessments for four major symptoms in the flied of supportive care. We conducted consultations for four clinical researches on research design, three clinical trials on statistical analysis and supported two clinical trials on quality management.


We held a seminar regarding behavioral science:

1)Motohiro Nakajima, PhD (The University of Minnesota): Biopsychosocial correlates of smoking relapse: current findings and future directions

Future prospects

We are planning to start an evaluation research with a view of provision for making a cancer survivorship guideline. We plan to promote behavioral and health care delivery research for bridging evidence-practice gaps in the field of cancer survivorship. And we will continue to provide a consultation on research design and statistical analysis, and support clinical trials in terms of quality management.

List of papers published in 2016


1.Kawashima Y, Nishi D, Noguchi H, Usuki M, Yamashita A, Koido Y, Okubo Y, Matsuoka YJ. Post-Traumatic Stress Symptoms and Burnout Among Medical Rescue Workers 4 Years After the Great East Japan Earthquake: A Longitudinal Study. Disaster Med Public Health Prep, 10:848-853, 2016

2.Usuda K, Nishi D, Makino M, Tachimori H, Matsuoka Y, Sano Y, Konishi T, Takeshima T. Prevalence and related factors of common mental disorders during pregnancy in Japan: a cross-sectional study. Biopsychosoc Med, 10:17, 2016

3.Nishi D, Kawashima Y, Noguchi H, Usuki M, Yamashita A, Koido Y, Matsuoka YJ. Resilience, post-traumatic growth, and work engagement among health care professionals after the Great East Japan Earthquake: A 4-year prospective follow-up study. J Occup Health, 58:347-353, 2016

4.Yoshikawa E, Nishi D, Matsuoka YJ. Association between regular physical exercise and depressive symptoms mediated through social support and resilience in Japanese company workers: a cross-sectional study. BMC Public Health, 16:553, 2016

5.Matsuoka YJ, Hamazaki K, Nishi D, Hamazaki T. Change in blood levels of eicosapentaenoic acid and posttraumatic stress symptom: A secondary analysis of data from a placebo-controlled trial of omega3 supplements. J Affect Disord, 205:289-291, 2016

6.Tanisho Y, Shigemura J, Kubota K, Tanigawa T, Bromet EJ, Takahashi S, Matsuoka Y, Nishi D, Nagamine M, Harada N, Tanichi M, Takahashi Y, Shimizu K, Nomura S, Yoshino A. The longitudinal mental health impact of Fukushima nuclear disaster exposures and public criticism among power plant workers: the Fukushima NEWS Project study. Psychol Med, 46:3117-3125, 2016

7.Yoshikawa E, Nishi D, Matsuoka YJ. Association between frequency of fried food consumption and resilience to depression in Japanese company workers: a cross-sectional study. Lipids Health Dis, 15:156, 2016

8.Nishi D, Su K-P, Usuda K, Chiang Y-JJ, Guu T-W, Hamazaki K, Nakaya N, Sone T, Sano Y, Tachibana Y, Ito H, Isaka K, Hashimoto K, Hamazaki T, Matsuoka YJ. The synchronized trial on expectant mothers with depressive symptoms by omega-3 PUFAs (SYNCHRO): Study protocol for a randomized controlled trial. BMC Psychiatry, 16:321, 2016