Annual Report 2020
Division of Surgical Technology
Masaaki Ito, Takahiro Kinoshita, Nobuyoshi Takeshita
Introduction
The main purpose of the Division of Surgical Technology is to develop surgical devices that are truly necessary, to deliver them to the clinical fields, and to prove the safety and efficacy through clinical trials.The three main elements of our innovation are creating devices reflecting true needs in the medical field, practicing with the devices in clinical trials and connecting our innovations to a wider world.
The Team and What We Do
By cooperation with the NEXT (Center for of New Surgical and Endoscopic Development for Exploratory Technology), we have started to promote the surgical device development consisting of clinical need selection, prototype design, POC (Proof of Concept) establishment, validation, and clinical trials.In addition, we will create an innovative medical development roadmap by establishing a hub for the surgical device development in National Cancer Center Hospital, East (NCCE) and building up the clinical supportive team for early-phase surgical device development.
Research activities
1. Cooperation with the NEXT
We have strengthened the system and the surgical device development in cooperation with the NEXT, based on discussion among professionals consisting of surgeons and coordinators for surgical innovation, intellectual property and pharmaceutical affairs.
2. Innovative surgical robotic system developed by NCC-certified venture company, A-Traction
In collaboration with an NCC-certified venture company, A-Traction, established in 2015, we have developed the innovative surgical robotic system.The system can support laparoscopic surgery as an assistant beside a surgeon. After the prototyping, we have advanced to verification for commercialization to obtain a manufacturing and distribution license approval.
3. Platform development for the system for clinical trial operations
As a specific clinical study on the surgical application of oxygen saturation imaging developed at our hospital, we set up a "pilot study on intestinal blood flow evaluation using oxygen saturation imaging" (scheduled to start in 2021).
4. Activities to match needs and seeds
In order to create opportunities for medical device development by regional companies, we cooperated with Chiba Prefecture for the event "Medical Needs Matching meeting in CHIBA" of the health and medical manufacturing industry support project in Chiba Prefecture.
Education
We held regular in-house seminars to teach surgical device innovation for the development of human resources.
Future Prospects
We aim to establish a clinical support team for early-phase surgical device innovation and aim to make a roadmap for surgical device innovation.
List of papers published in 2020
Journal
1. Shiraishi T, Ikeda K, Tsukada Y, Nishizawa Y, Sasaki T, Ito M, Kojima M, Ishii G, Tsumura R, Saijou S, Koga Y, Yasunaga M, Matsumura Y. High expression of TMEM180, a novel tumour marker, is associated with poor survival in stage III colorectal cancer. BMC Cancer, 21:302, 2021
2. Kitaguchi D, Takeshita N, Matsuzaki H, Hasegawa H, Honda R, Teramura K, Oda T, Ito M. Computer-assisted real-time automatic prostate segmentation during TaTME: a single-center feasibility study. Surg Endosc, 35:2493-2499, 2021
3. Narihiro S, Miura N, Nishizawa Y, Hasegawa H, Ikeda K, Teramura K, Tsukada Y, Sasaki T, Ito M. Delorme surgery for colonic mucosal prolapse after intersphincteric resection. Surg Today, 51:916-922, 2021
4. Shiraishi T, Ito M, Sasaki T, Nishizawa Y, Tsukada Y, Ikeda K. Association between urinary function and resected pattern of the autonomic nerve system after transanal total mesorectal excision for rectal cancer. Colorectal Dis, 23:405-414, 2021
5. Enomoto H, Nishizawa Y, Inamori K, Hasegawa H, Ikeda K, Tsukada Y, Sasaki T, Ito M. Sacral neuromodulation for the prevention of a permanent stoma in patients with severe defecation disorder following intersphincteric resection. Surg Today, 2021
6. Kondo A, Nishizawa Y, Tsukada Y, Sasaki T, Inoue M, Masuda H, Suzuki Y, Ito M. Potential benefit of laparoscopic surgery for rectal cancer on postoperative male sexual function. Colorectal Dis, 2021
7. Ito M, Yamamoto S, Okuda J, Fujii S, Yamaguchi S, Otsuka K, Yoshimura K, Watanabe M. Long-term survival outcomes following laparoscopic surgery for clinical stage 0/I rectal carcinoma. Ann Gastroenterol Surg, 4:294-300, 2020
8. Kitaguchi D, Takeshita N, Matsuzaki H, Oda T, Watanabe M, Mori K, Kobayashi E, Ito M. Automated laparoscopic colorectal surgery workflow recognition using artificial intelligence: Experimental research. Int J Surg, 79:88-94, 2020
9. Shiraishi T, Nishizawa Y, Ikeda K, Tsukada Y, Sasaki T, Ito M. Risk factors for parastomal hernia of loop stoma and relationships with other stoma complications in laparoscopic surgery era. BMC Surg, 20:141, 2020
10. Kitaguchi D, Takeshita N, Matsuzaki H, Takano H, Owada Y, Enomoto T, Oda T, Miura H, Yamanashi T, Watanabe M, Sato D, Sugomori Y, Hara S, Ito M. Real-time automatic surgical phase recognition in laparoscopic sigmoidectomy using the convolutional neural network-based deep learning approach. Surg Endosc, 34:4924-4931, 2020
11. Imai S, Ito M. A novel surgical training simulator for transanal total mesorectal excision. Tech Coloproctol, 24:1163-1168, 2020
12. Ito M. ISR for T1-2 Low Rectal Cancer: A Japanese Approach. Clin Colon Rectal Surg, 33:361-365, 2020
Book
1. Ito M. Robotic Surgery: Currently and in the Near Future. In: Takenoshita S, Yasuhara H (eds), Surgery and Operating Room Innovation, Singapore, Springer Singapore, pp 125-131, 2021