Annual Report 2021
Department of Pediatric Surgery
Akihiro Yoneda, Junnosuke Maniwa
Introduction
The Department of Pediatric Surgery was newly established in April 2016 to provide surgical treatment for pediatric cancers. Our team specializes in surgeries for a wide variety of tumors including neuroblastomas, nephroblastomas (renal tumors), hepatoblastomas (liver tumors), Ewing sarcomas, rhabdomyosarcomas, osteosarcomas, germ cell tumors, metastatic lung tumors and all other types of tumors arising in children and adolescents.
The Team and What We Do
The outpatient service of our department treats newly diagnosed patients and provides follow-up treatment for patients who received surgery. Weekly conferences are held with pediatric oncologists from the Department of Pediatric Oncology.
We particularly specialize in performing surgical operations on infants and small children but also care for adolescent and young adult (AYA) patients in collaboration with expert surgeons of our adult team.
Research activities
Our staff members play key roles in nationwide collaborative studies. We are also involved in translational research activities on immunotherapy for neuroblastoma and other solid tumors.
Clinical trials
We have a leading role in clinical trials conducted by the Japanese Childhood Cancer Group (JCCG), with particular interest in neuroblastoma.
Education
We are accepting trainees and students worldwide and nationwide.
Future Prospects
Pediatric cancers that are cured by surgery alone are very rare. Multidisciplinary treatment combined with surgery, chemotherapy and radiotherapy is often needed to treat such diseases. We collaborate with the Department of Pediatric Oncology and other related departments and provide advanced treatment for pediatric and AYA patients with cancer.
List of papers published in 2021
Journal
1. Kawano T, Souzaki R, Sumida W, Ishimaru T, Fujishiro J, Hishiki T, Kinoshita Y, Kawashima H, Uchida H, Tajiri T, Yoneda A, Oue T, Kuroda T, Koshinaga T, Hiyama E, Nio M, Inomata Y, Taguchi T, Ieiri S. Laparoscopic approach for abdominal neuroblastoma in Japan: results from nationwide multicenter survey. Surgical endoscopy, 36:3028-3038, 2022
2. Ohira M, Nakamura Y, Takimoto T, Nakazawa A, Hishiki T, Matsumoto K, Shichino H, Iehara T, Nagase H, Fukushima T, Yoneda A, Tajiri T, Nakagawara A, Kamijo T. Retrospective Analysis of INRG Clinical and Genomic Factors for 605 Neuroblastomas in Japan: A Report from the Japan Children's Cancer Group Neuroblastoma Committee (JCCG-JNBSG). Biomolecules, 12:2021
3. Zenitani M, Tsukada R, Masahata K, Nakamura K, Takama Y, Umeda S, Soh H, Yoneda A, Yonekura T, Usui N, Oue T, Okuyama H. Safety and Feasibility of Laparoscopic Resection of Neuroblastoma Without Image-Defined Risk Factors Performed by Pediatric Surgical Trainees: A Multicenter Comparison Study. Journal of laparoendoscopic & advanced surgical techniques. Part A, 31:954-958, 2021
4. Yamamichi T, Oue T, Irie A, Inoue M, Takama Y, Nomura M, Yoneda A, Okuyama H, Usui N. Results of mass screening for neuroblastoma in 18-month-old infants in Osaka area, Japan. Pediatric surgery international, 37:1645-1649, 2021
5. Nakamura K, Yamada H, Kamiyama M, Inoue T, Yoneda A. Uncapsulized sacrococcygeal teratoma in a neonate. Pediatrics international: official journal of the Japan Pediatric Society, 63:1266-1267, 2021
6. Kawano T, Souzaki R, Sumida W, Shimojima N, Hishiki T, Kinoshita Y, Uchida H, Tajiri T, Yoneda A, Oue T, Kuroda T, Hirobe S, Koshinaga T, Hiyama E, Nio M, Inomata Y, Taguchi T, Ieiri S. Current thoracoscopic approach for mediastinal neuroblastoma in Japan-results from nationwide multicenter survey. Pediatric surgery international, 37:1651-1658, 2021
7. Fukushima H, Yamasaki K, Sakaida M, Tsujio N, Okuno T, Ishii N, Okada K, Fujisaki H, Matsusaka Y, Sakamoto H, Yoneda A, Hara J, Inoue T. Rhabdoid tumor predisposition syndrome with renal tumor 10 years after brain tumor. Pathology international, 71:155-160, 2021