Annual Report 2022
Department of Pediatric Surgery
Akihiro Yoneda, Junkichi Takemoto
Introduction
The Department of Pediatric Surgery was established in April 2016 to provide surgical treatment for pediatric cancers. Our team specializes in surgeries for a wide variety of tumors including neuroblastomas, nephroblastomas (renal tumors), hepatoblastomas (liver tumors), Ewing sarcomas, rhabdomyosarcomas, osteosarcomas, germ cell tumors, metastatic lung tumors and all other types of tumors arising in children and adolescents.
The Team and What We Do
The outpatient service of our department includes treating newly diagnosed patients and providing follow-up treatment for patients who underwent surgery. Weekly conferences are held with pediatric oncologists from the Department of Pediatric Oncology.
We specialize in performing surgical operations on infants and small children and also care for adolescent and young adult (AYA) patients in collaboration with expert surgeons of our adult team.
Research Activities
Our staff members play key roles in nationwide collaborative studies. We are also involved in translational research activities on immunotherapy for neuroblastoma and other solid tumors.
Clinical Trials
We play a leading role in clinical trials conducted by the Japanese Childhood Cancer Group (JCCG), with particular interest in neuroblastoma.
Education
We are accepting trainees and students worldwide and nationwide.
Future Prospects
Pediatric cancers treated by surgery alone are rare. Thus, multidisciplinary treatment combined with surgery, chemotherapy and radiotherapy is often necessary to treat such diseases. We will collaborate with the Department of Pediatric Oncology and other related departments and provide advanced treatment for pediatric and AYA patients with cancer.
List of papers published in 2022
Journal
1. Shirai R, Osumi T, Sato-Otsubo A, Nakabayashi K, Ishiwata K, Yamada Y, Yoshida M, Yoshida K, Shioda Y, Kiyotani C, Terashima K, Tomizawa D, Takasugi N, Takita J, Miyazaki O, Kiyokawa N, Yoneda A, Kanamori Y, Hishiki T, Matsumoto K, Hata K, Yoshioka T, Kato M. Quantitative assessment of copy number alterations by liquid biopsy for neuroblastoma. Genes, chromosomes & cancer, 61:662-669, 2022
2. Kawakubo N, Takemoto J, Koga Y, Hino Y, Tamaki A, Kohashi K, Ono H, Oda Y, Ohga S, Tajiri T. The utility of core-needle tumor biopsy for pediatric patients. Pediatrics international, 64:e15228, 2022
3. Kano M, Furugane R, Hogetsu K, Yamada Y, Maniwa J, Kobayashi T, Hashizume N, Mori T, Watanabe E, Takahashi M, Fujino A, Kanamori Y, Terashima K, Matsumoto K, Yoneda A. Vaginal yolk sac tumor resected by a novel laparo/endoscope-assisted posterior sagittal approach: a case report. Surgical case reports, 8:162, 2022
4. Omori A, Kawakubo N, Takemoto J, Souzaki R, Obata S, Nagata K, Matsuura T, Tajiri T, Taguchi T. Effects of changes in skeletal muscle mass on the prognosis of pediatric malignant solid tumors. Pediatric surgery international, 38:1829-1838, 2022
5. Hashizume N, Yoneda A, Kano M, Yoshii S, Uehara Y, Fujino A, Kanamori Y. A case of enormous congenital cervicofacial immature teratoma. Pediatrics international, 64:e15394, 2022
6. Watanabe E, Hashizume N, Yoneda A, Kasahara M, Ozeki G, Saito T, Fujiogi M, Kano M, Yamamoto Y, Miyazaki O, Maekawa T, Nakano N, Yoshioka T, Fujino A, Kanamori Y. Infantile Kaposiform hemangioendothelioma in a female patient complicated with severe obstructed jaundice: a case report. Surgical case reports, 8:225, 2022