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Research Papers


  1. Imai T, Naruse M, Ochiai M, Matsumoto K, Ikeda S, Kani M, Kato Y, Hirayama A, Soga T, Hori Y, Yokoi A, Ochiai A. Different types of reactions to E7386 among colorectal cancer patient-derived organoids and corresponding CAFs. Oncol. Lett. (In press)
  2. Naruse M, Ishigamori R, Imai T. The unique genetic and histological characteristics of DMBA-induced mammary tumors in an organoid-based carcinogenesis model. Front. Genet., 12: 768781, 2021 PMID: 34912374
  3. Komiya M, Ishigamori R, Naruse M, Ochiai M, Miyoshi N, Imai T, Totsuka Y. Establishment of novel genotoxicity assay system using murine normal epithelial tissue-derived organoids. Front. Genet., 12: 765131, 2021 PMID: 34868254
  4. Machida Y, Imai T. Different properties of mammary carcinogenesis induced by two chemical carcinogens, DMBA and PhIP, in heterozygous BALB/c Trp53 knockout mice. Oncol. Lett., 22: 738, 2021 PMID: 34466150
  5. Naruse M, Ochiai M, Sekine S, Taniguchi H, Yoshida T, Ichikawa H, Sakamoto H, Kubo T, Matsumoto K, Ochiai A, Imai T. Re-expression of REG family and DUOXs genes in CRC organoids by co-culturing with CAFs. Sci. Rep., 11: 2077, 2021 PMID: 33483567
  6. Naruse M, Masui R, Ochiai M, Maru Y, Hippo Y, Imai T. An organoid-based carcinogenesis model induced by in vitro chemical treatment. Carcinogenesis, 41: 10.1444-1453, 2020 PMID: 32047892
  7. Yonemaru J, Takahashi M, Nara S, Ichikawa H, Ishigamori R, Imai T, Hiraoka H. A yolk sac tumor of the pancreas and derived xenograft model effectively responded to VIP chemotherapy. Pancreatol, 20: 551-557, 2020 PMID: 31917123
  8. Machida Y, Sudo Y, Uchiya N, Imai T. Increased susceptibility to mammary carcinogenesis and an opposite trend in endometrium in Trp53 heterozygous knockout female mice by back-crossing the BALB/c strain onto the background C3H strain. J. Toxicol. Pathol., 32: 197-203, 2019 PMID: 31404346
  9. Takahashi M, Hori M, Ishigamori R, Mutoh M, Imai T, Nakagama H. Fatty pancreas: A possible risk factor for pancreatic cancer in animals and humans. Cancer Sci., 109: 3013-3023, 2018 PMID: 30099827