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Research Support Services
Whole Exome Sequencing (WES) Analysis
For studies with matched tumor and normal samples, we perform comprehensive analyses including somatic variant detection, copy number alteration analysis, tumor mutational burden (TMB) estimation, microsatellite instability (MSI) scoring, and homologous recombination deficiency (HRD) scoring.
When multiple samples are available, cohort-level analyses such as OncoPrint visualization and mutational signature analysis are also performed. To facilitate data interpretation, we provide an interactive HTML report that presents key findings in a clear and visually intuitive manner, enabling researchers to quickly grasp the overall genomic landscape of their study.
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Somatic mutation VAF plot
CNV
OncoPrint
Whole Genome Sequencing (WGS) Analysis
In addition to the analyses performed for WES data, WGS provides a more comprehensive view of the genome by enabling the detection of structural variations (SVs) and genome-wide copy number alterations, as well as other large-scale genomic events.
SV & CNV
RNA-sequencing Analysis
In addition to gene expression quantification and fusion gene detection, we perform differential expression analysis between sample groups and identify aberrant splicing events from RNA-seq data.
Expression heatmap
TPM
Volcano plot
Fusion
Custom Bioinformatics Analysis
We provide customized bioinformatics support for a wide range of NGS-based applications, including CRISPR screening studies and other specialized analyses. We are also able to develop and adapt analytical workflows for projects that cannot be readily addressed using standard pipelines.
In addition, we offer support for the installation and configuration of bioinformatics software and analysis environments on Linux-based systems.
Because custom projects often involve unique research questions and technical requirements, we welcome early consultation and discussion. Please feel free to contact us to explore potential analytical approaches for your project.
