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Home > Organization > Divisions and Independent Research Units > Division of Cancer Evolution > Research Papers > 2019

2019

  1. Berger, G., Gerritsen, M., Yi, G., Koorenhof-Scheele, T. N., Kroeze, L. I., Stevens-Kroef, M., Yoshida K., Shiraishi, Y., van den Berg, E., Schepers, H., Huls, G., Mulder, A. B., Ogawa, S., Martens, J. H. A., Jansen, J. H., Vellenga, E.: Ring sideroblasts in AML are associated with adverse risk characteristics and have a distinct gene expression pattern. Blood Adv, 3: 3111-3122 (2019).
  2. Christen, F., Hoyer, K., Yoshida K., Hou, H. A., Waldhueter, N., Heuser, M., Hills, R. K., Chan, W., Hablesreiter, R., Blau, O., Ochi, Y., Klement, P., Chou, W. C., Blau, I. W., Tang, J. L., Zemojtel, T., Shiraishi, Y., Shiozawa, Y., Thol, F., Ganser, A., Lowenberg, B., Linch, D. C., Bullinger, L., Valk, P. J. M., Tien, H. F., Gale, R. E., Ogawa, S., Damm, F.: Genomic landscape and clonal evolution of acute myeloid leukemia with t(8;21): an international study on 331 patients. Blood, 133: 1140-1151 (2019).
  3. Frick, M., Chan, W., Arends, C. M., Hablesreiter, R., Halik, A., Heuser, M., Michonneau, D., Blau, O., Hoyer, K., Christen, F., Galan-Sousa, J., Noerenberg, D., Wais, V., Stadler, M., Yoshida K., Schetelig, J., Schuler, E., Thol, F., Clappier, E., Christopeit, M., Ayuk, F., Bornhauser, M., Blau, I. W., Ogawa, S., Zemojtel, T., Gerbitz, A., Wagner, E. M., Spriewald, B. M., Schrezenmeier, H., Kuchenbauer, F., Kobbe, G., Wiesneth, M., Koldehoff, M., Socie, G., Kroeger, N., Bullinger, L., Thiede, C., Damm, F.: Role of Donor Clonal Hematopoiesis in Allogeneic Hematopoietic Stem-Cell Transplantation. J Clin Oncol, 37: 375-385 (2019).
  4. Haase, D., Stevenson, K. E., Neuberg, D., Maciejewski, J. P., Nazha, A., Sekeres, M. A., Ebert, B. L., Garcia-Manero, G., Haferlach, C., Haferlach, T., Kern, W., Ogawa, S., Nagata, Y., Yoshida K., Graubert, T. A., Walter, M. J., List, A. F., Komrokji, R. S., Padron, E., Sallman, D., Papaemmanuil, E., Campbell, P. J., Savona, M. R., Seegmiller, A., Ades, L., Fenaux, P., Shih, L. Y., Bowen, D., Groves, M. J., Tauro, S., Fontenay, M., Kosmider, O., Bar-Natan, M., Steensma, D., Stone, R., Heuser, M., Thol, F., Cazzola, M., Malcovati, L., Karsan, A., Ganster, C., Hellstrom-Lindberg, E., Boultwood, J., Pellagatti, A., Santini, V., Quek, L., Vyas, P., Tuchler, H., Greenberg, P. L., Bejar, R., International Working Group for, M. D. S. M. P. C.: TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroups. Leukemia, 33: 1747-1758 (2019).
  5. Hoshino, A., Yang, X., Tanita, K., Yoshida K., Ono, T., Nishida, N., Okuno, Y., Kanzaki, T., Goi, K., Fujino, H., Ohshima, K., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Ogawa, S., Kojima, S., Morio, T., Kanegane, H.: Modification of cellular and humoral immunity by somatically reverted T cells in X-linked lymphoproliferative syndrome type 1. J Allergy Clin Immunol, 143: 421-424 e411 (2019).
  6. Kataoka, K., Miyoshi, H., Sakata, S., Dobashi, A., Couronne, L., Kogure, Y., Sato, Y., Nishida, K., Gion, Y., Shiraishi, Y., Tanaka, H., Chiba, K., Watatani, Y., Kakiuchi, N., Shiozawa, Y., Yoshizato, T., Yoshida K., Makishima, H., Sanada, M., Onozawa, M., Teshima, T., Yoshiki, Y., Ishida, T., Suzuki, K., Shimada, K., Tomita, A., Kato, M., Ota, Y., Izutsu, K., Demachi-Okamura, A., Akatsuka, Y., Miyano, S., Yoshino, T., Gaulard, P., Hermine, O., Takeuchi, K., Ohshima, K., Ogawa, S.: Frequent structural variations involving programmed death ligands in Epstein-Barr virus-associated lymphomas. Leukemia, 33: 1687-1699 (2019).
  7. Kim, S. K., Takeda, H., Takai, A., Matsumoto, T., Kakiuchi, N., Yokoyama, A., Yoshida K., Kaido, T., Uemoto, S., Minamiguchi, S., Haga, H., Shiraishi, Y., Miyano, S., Seno, H., Ogawa, S., Marusawa, H.: Comprehensive analysis of genetic aberrations linked to tumorigenesis in regenerative nodules of liver cirrhosis. J Gastroenterol, 54: 628-640 (2019).
  8. Kimura, S., Seki, M., Yoshida K., Shiraishi, Y., Akiyama, M., Koh, K., Imamura, T., Manabe, A., Hayashi, Y., Kobayashi, M., Oka, A., Miyano, S., Ogawa, S., Takita, J.: NOTCH1 pathway activating mutations and clonal evolution in pediatric T-cell acute lymphoblastic leukemia. Cancer Sci, 110: 784-794 (2019).
  9. Kobayashi, K., Mizuta, S., Yamane, N., Ueno, H., Yoshida K., Kato, I., Umeda, K., Hiramatsu, H., Suehiro, M., Maihara, T., Usami, I., Shiraishi, Y., Chiba, K., Miyano, S., Adachi, S., Ogawa, S., Kiyokawa, N., Heike, T.: Paraneoplastic hypereosinophilic syndrome associated with IL3-IgH positive acute lymphoblastic leukemia. Pediatr Blood Cancer, 66: e27449 (2019).
  10. Kohara, H., Utsugisawa, T., Sakamoto, C., Hirose, L., Ogawa, Y., Ogura, H., Sugawara, A., Liao, J., Aoki, T., Iwasaki, T., Asai, T., Doisaki, S., Okuno, Y., Muramatsu, H., Abe, T., Kurita, R., Miyamoto, S., Sakuma, T., Shiba, M., Yamamoto, T., Ohga, S., Yoshida K., Ogawa, S., Ito, E., Kojima, S., Kanno, H., Tani, K.: KLF1 mutation E325K induces cell cycle arrest in erythroid cells differentiated from congenital dyserythropoietic anemia patient-specific induced pluripotent stem cells. Exp Hematol, 73: 25-37 e28 (2019).
  11. Kotani, S., Yoda, A., Kon, A., Kataoka, K., Ochi, Y., Shiozawa, Y., Hirsch, C., Takeda, J., Ueno, H., Yoshizato, T., Yoshida K., Nakagawa, M. M., Nannya, Y., Kakiuchi, N., Yamauchi, T., Aoki, K., Shiraishi, Y., Miyano, S., Maeda, T., Maciejewski, J. P., Takaori-Kondo, A., Ogawa, S., Makishima, H.: Molecular pathogenesis of disease progression in MLL-rearranged AML. Leukemia, 33: 612-624 (2019).
  12. Kubota, Y., Uryu, K., Ito, T., Seki, M., Kawai, T., Isobe, T., Kumagai, T., Toki, T., Yoshida K., Suzuki, H., Kataoka, K., Shiraishi, Y., Chiba, K., Tanaka, H., Ohki, K., Kiyokawa, N., Kagawa, J., Miyano, S., Oka, A., Hayashi, Y., Ogawa, S., Terui, K., Sato, A., Hata, K., Ito, E., Takita, J.: Integrated genetic and epigenetic analysis revealed heterogeneity of acute lymphoblastic leukemia in Down syndrome. Cancer Sci, 110: 3358-3367 (2019).
  13. Mori, M., Hira, A., Yoshida K., Muramatsu, H., Okuno, Y., Shiraishi, Y., Anmae, M., Yasuda, J., Tadaka, S., Kinoshita, K., Osumi, T., Noguchi, Y., Adachi, S., Kobayashi, R., Kawabata, H., Imai, K., Morio, T., Tamura, K., Takaori-Kondo, A., Yamamoto, M., Miyano, S., Kojima, S., Ito, E., Ogawa, S., Matsuo, K., Yabe, H., Yabe, M., Takata, M.: Pathogenic mutations identified by a multimodality approach in 117 Japanese Fanconi anemia patients. Haematologica, 104: 1962-1973 (2019).
  14. Nagao, Y., Mimura, N., Takeda, J., Yoshida K., Shiozawa, Y., Oshima, M., Aoyama, K., Saraya, A., Koide, S., Rizq, O., Hasegawa, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Nishijima, D., Isshiki, Y., Kayamori, K., Kawajiri-Manako, C., Oshima-Hasegawa, N., Tsukamoto, S., Mitsukawa, S., Takeda, Y., Ohwada, C., Takeuchi, M., Iseki, T., Misawa, S., Miyano, S., Ohara, O., Yokote, K., Sakaida, E., Kuwabara, S., Sanada, M., Iwama, A., Ogawa, S., Nakaseko, C.: Genetic and transcriptional landscape of plasma cells in POEMS syndrome. Leukemia, 33: 1723-1735 (2019).
  15. Nagata, Y., Makishima, H., Kerr, C. M., Przychodzen, B. P., Aly, M., Goyal, A., Awada, H., Asad, M. F., Kuzmanovic, T., Suzuki, H., Yoshizato, T., Yoshida K., Chiba, K., Tanaka, H., Shiraishi, Y., Miyano, S., Mukherjee, S., LaFramboise, T., Nazha, A., Sekeres, M. A., Radivoyevitch, T., Haferlach, T., Ogawa, S., Maciejewski, J. P.: Invariant patterns of clonal succession determine specific clinical features of myelodysplastic syndromes. Nat Commun, 10: 5386 (2019).
  16. Okano, T., Imai, K., Tsujita, Y., Mitsuiki, N., Yoshida K., Kamae, C., Honma, K., Mitsui-Sekinaka, K., Sekinaka, Y., Kato, T., Hanabusa, K., Endo, E., Takashima, T., Hiroki, H., Yeh, T. W., Tanaka, K., Nagahori, M., Tsuge, I., Bando, Y., Iwasaki, F., Shikama, Y., Inoue, M., Kimoto, T., Moriguchi, N., Yuza, Y., Kaneko, T., Suzuki, K., Matsubara, T., Maruo, Y., Kunitsu, T., Waragai, T., Sano, H., Hashimoto, Y., Tasaki, K., Suzuki, O., Shirakawa, T., Kato, M., Uchiyama, T., Ishimura, M., Tauchi, T., Yagasaki, H., Jou, S. T., Yu, H. H., Kanegane, H., Kracker, S., Durandy, A., Kojima, D., Muramatsu, H., Wada, T., Inoue, Y., Takada, H., Kojima, S., Ogawa, S., Ohara, O., Nonoyama, S., Morio, T.: Hematopoietic stem cell transplantation for progressive combined immunodeficiency and lymphoproliferation in patients with activated phosphatidylinositol-3-OH kinase delta syndrome type 1. J Allergy Clin Immunol, 143: 266-275 (2019).
  17. Okuno, Y., Murata, T., Sato, Y., Muramatsu, H., Ito, Y., Watanabe, T., Okuno, T., Murakami, N., Yoshida K., Sawada, A., Inoue, M., Kawa, K., Seto, M., Ohshima, K., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Narita, Y., Yoshida, M., Goshima, F., Kawada, J. I., Nishida, T., Kiyoi, H., Kato, S., Nakamura, S., Morishima, S., Yoshikawa, T., Fujiwara, S., Shimizu, N., Isobe, Y., Noguchi, M., Kikuta, A., Iwatsuki, K., Takahashi, Y., Kojima, S., Ogawa, S., Kimura, H.: Defective Epstein-Barr virus in chronic active infection and haematological malignancy. Nat Microbiol, 4: 404-413 (2019).
  18. Ono, S., Matsuda, J., Watanabe, E., Akaike, H., Teranishi, H., Miyata, I., Otomo, T., Sadahira, Y., Mizuochi, T., Kusano, H., Kage, M., Ueno, H., Yoshida K., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Ogawa, S., Hayashi, Y., Kanegane, H., Ouchi, K.: Novel neuroblastoma amplified sequence (NBAS) mutations in a Japanese boy with fever-triggered recurrent acute liver failure. Hum Genome Var, 6: 2 (2019).
  19. Polprasert, C., Takeuchi, Y., Kakiuchi, N., Yoshida K., Assanasen, T., Sitthi, W., Bunworasate, U., Pirunsarn, A., Wudhikarn, K., Lawasut, P., Uaprasert, N., Kongkiatkamon, S., Moonla, C., Sanada, M., Akita, N., Takeda, J., Fujii, Y., Suzuki, H., Nannya, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Rojnuckarin, P., Ogawa, S., Makishima, H.: Frequent germline mutations of HAVCR2 in sporadic subcutaneous panniculitis-like T-cell lymphoma. Blood Adv, 3: 588-595 (2019).
  20. Shiba, N., Yoshida K., Hara, Y., Yamato, G., Shiraishi, Y., Matsuo, H., Okuno, Y., Chiba, K., Tanaka, H., Kaburagi, T., Takeuchi, M., Ohki, K., Sanada, M., Okubo, J., Tomizawa, D., Taki, T., Shimada, A., Sotomatsu, M., Horibe, K., Taga, T., Adachi, S., Tawa, A., Miyano, S., Ogawa, S., Hayashi, Y.: Transcriptome analysis offers a comprehensive illustration of the genetic background of pediatric acute myeloid leukemia. Blood Adv, 3: 3157-3169 (2019).
  21. Takashima, Y., Kawaguchi, A., Sato, R., Yoshida K., Hayano, A., Homma, J., Fukai, J., Iwadate, Y., Kajiwara, K., Ishizawa, S., Hondoh, H., Nakano, M., Ogawa, S., Tashiro, K., Yamanaka, R.: Differential expression of individual transcript variants of PD-1 and PD-L2 genes on Th-1/Th-2 status is guaranteed for prognosis prediction in PCNSL. Sci Rep, 9: 10004 (2019).
  22. Watatani, Y., Sato, Y., Miyoshi, H., Sakamoto, K., Nishida, K., Gion, Y., Nagata, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Zhao, L., Ochi, Y., Takeuchi, Y., Takeda, J., Ueno, H., Kogure, Y., Shiozawa, Y., Kakiuchi, N., Yoshizato, T., Nakagawa, M. M., Nanya, Y., Yoshida K., Makishima, H., Sanada, M., Sakata-Yanagimoto, M., Chiba, S., Matsuoka, R., Noguchi, M., Hiramoto, N., Ishikawa, T., Kitagawa, J., Nakamura, N., Tsurumi, H., Miyazaki, T., Kito, Y., Miyano, S., Shimoda, K., Takeuchi, K., Ohshima, K., Yoshino, T., Ogawa, S., Kataoka, K.: Molecular heterogeneity in peripheral T-cell lymphoma, not otherwise specified revealed by comprehensive genetic profiling. Leukemia, 33: 2867-2883 (2019).
  23. Yabe, M., Koike, T., Ohtsubo, K., Imai, E., Morimoto, T., Takakura, H., Koh, K., Yoshida K., Ogawa, S., Ito, E., Okuno, Y., Muramatsu, H., Kojima, S., Matsuo, K., Mori, M., Hira, A., Takata, M., Yabe, H.: Associations of complementation group, ALDH2 genotype, and clonal abnormalities with hematological outcome in Japanese patients with Fanconi anemia. Ann Hematol, 98: 271-280 (2019).
  24. Yokoyama, A., Kakiuchi, N., Yoshizato, T., Nannya, Y., Suzuki, H., Takeuchi, Y., Shiozawa, Y., Sato, Y., Aoki, K., Kim, S. K., Fujii, Y., Yoshida K., Kataoka, K., Nakagawa, M. M., Inoue, Y., Hirano, T., Shiraishi, Y., Chiba, K., Tanaka, H., Sanada, M., Nishikawa, Y., Amanuma, Y., Ohashi, S., Aoyama, I., Horimatsu, T., Miyamoto, S., Tsunoda, S., Sakai, Y., Narahara, M., Brown, J. B., Sato, Y., Sawada, G., Mimori, K., Minamiguchi, S., Haga, H., Seno, H., Miyano, S., Makishima, H., Muto, M., Ogawa, S.: Age-related remodelling of oesophageal epithelia by mutated cancer drivers. Nature, 565: 312-317 (2019).
  25. Labuhn, M., Perkins, K., Matzk, S., Varghese, L., Garnett, C., Papaemmanuil, E., Metzner, M., Kennedy, A., Amstislavskiy, V., Risch, T., Bhayadia, R., Samulowski, D., Hernandez, DC., Stoilova, B., Iotchkova, V., Oppermann, U., Scheer, C., Yoshida, K., Schwarzer, A., Taub, JW., Crispino, JD., Weiss, MJ., Hayashi, Y., Taga, T., Ito, E., Ogawa, S., Reinhardt, D., Yaspo, ML., Campbell, PJ., Roberts, I., Constantinescu, SN., Vyas, P., Heckl, D., Klusmann, JH.: Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome. Cancer Cell, 36: 123-138 (2019)
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