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Home > Organization > Divisions and Independent Research Units > Division of Carcinogenesis and Prevention > Environmental Carcinogenesis and Cancer Prevention Group > Research Papers

Research Papers

2010

  1. Takeuchi H, Saoo K, Yamakawa K, Matsuda Y, Yokohira M, Zeng Y, Kuno T, Totsuka Y, Takahashi M, Wakabayashi K, Imaida K. Tumorigenesis of　2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx), but not enhancing effects of concomitant high-fat diet, on lung carcinogenesis in female A/J mice. Oncol Lett. 2010 Jan; 1(1): 137-42.
  2. Ichijima Y, Yoshioka K, Yoshioka Y, Shinohe K, Fujimori H, Unno J, Takagi M, Goto H, Inagaki I, Mizutani S, Teraoka H. DNA lesions induced by replication stress trigger mitotic aberration and tetraploidy development. PLoS ONE 2010; 5: e8821.
  3. Kitahashi T, Mutoh M, Tsurusaki M, Iinuma G, Suzuki M, Moriyama N, Yoshimoto M, Wakabayashi K, Sugimura T, Imai T. Imaging study of pancreatic ductal adenocarcinomas in Syrian hamsters using X-ray micro-computed tomography (CT). Cancer Sci. 2010; 101: 1761-6.

2011

  1. Wei M, Wanibuchi H, Nakae D, Tsuda H, Takahashi S, Hirose M, Totsuka Y, Tatematsu M, Fukushima S. Low-dose carcinogenicity of 2-amino-3-methylimidazo[4,5-f]quinoline in rats: Evidence for the existence of no-effect levels and a mechanism involving p21(Cip/WAF1). Cancer Sci. 2011; 102: 88-94.
  2. Totsuka Y, Kato T, Masuda S, Ishino K, Matsumoto Y, Goto S, Kawanishi M, Yagi T, Wakabayashi K., In vitro and in vivo genotoxicity induced by fullerene (C60) and kaolin. Genes Environ. 2011; 33: 14-20.
  3. Lin Y, Ueda J, Kikuchi S, Totsuka Y, Wei W, Qiao Y, Inoue M. Comparative epidemiology of gastric cancer between Japan and China. World J Gastroenterol. 2011; 17: 4421-8.
  4. Yamamoto M, Takahashi-Nakaguchi A, Matsushima-Hibiya Y, Nakano T, Totsuka Y, Imanishi S, Mitsuhashi J, Watanabe M, Nakagama H, Sugimura T, Wakabayashi K. Nucleotide sequence and chromosomal localization of the gene for pierisin-1, a DNA ADP-ribosylating protein, in the cabbage butterfly Pieris rapae. Genetica. 2011; 139(10): 1251-8.
  5. Atsumi Y, Fujimori H, Fukuda H, Inase A, Shinohe K, Yoshioka Y, Shikanai M, Ichijima Y, Unno J, Mizutani S, Tsuchiya N, Hippo Y, Nakagama H, Masutani M, Teraoka H, Yoshioka K. Onset of quiescence following p53 mediated down-regulation of H2AX in normal cells. PLoS ONE 2011; 6: e23432.
  6. Teraoka N, Mutoh M, Takasu S, Ueno T, Nakano K, Takahashi M, Imai T, Masuda S, Sugimura T, Wakabayashi K. High susceptibility to azoxymethane-induced colorectal carcinogenesis in obese KK-Ay mice. Int J Cancer. 2011; 129(3): 528-35.
  7. Ikeda K, Mutoh M, Teraoka N, Nakanishi H, Wakabayashi K, Taguchi R. Increase of oxidant-related triglycerides and phosphatidylcholines inserun and small intestinal mucosa during development of intestinal polyp formation in Min mice. Cancer Sci. 2011; 102(1): 79-87.
  8. Takahashi M, Hori M, Mutoh M, Wakabayashi K, Nakagama H. Experimental animal models of pancreatic carcinogenesis for prevention studies and their relevance to human disease. Cancers (Basel). 2011; 3(1): 582-602.
  9. Teraoka N, Mutoh M, Takasu S, Ueno T, Yamamoto M, Sugimura T, Wakabayashi K. Inhibition of intestinal polyp formation by pitavastatin, a HMG-CoA reductase inhibitor. Cancer Prev Res (Phila). 2011; 4(3): 445-53.
  10. Mutoh M, Teraoka N, Takasu S, Takahashi M, Onuma K, Yamamoto M, Kubota N, Iseki T, Kadowaki T, Sugimura T, Wakabayashi K. Loss of adiponectin promotes intestinal carcinogenesis in Min and wild-type mice. Gastroenterology 2011; 140(7): 2000-8.
  11. Hori M, Kitahashi T, Imai T, Ishigamori R, Takasu S, Mutoh M, Sugimura T, Wakabayashi K, Takahashi M. Enhancement of carcinogenesis and fatty infiltration in the pancreas in N-nitrosobis(2-oxopropyl)amine-treated hamsters by high-fat diet. Pancreas 2011; 40(8): 1234-40.
  12. Fujii G, Yamamoto M, Takahashi M, Mutoh M. Role of adipocytokines in colorectal carcinogenesis. Curr Res in Cancer 2011; 5: 39-48.

2012

  1. Matsubara S, Takasu S, Tsukamoto T, Mutoh M, Masuda S, Sugimura T, Wakabayashi K, Totsuka Y. Induction of glandular stomach cancers in Helicobacter pylori-infected Mongolian Gerbils by 1-Nitrosoindole-3-acetonitrile. Int J Cancer 2012; 130(2): 259-66.
  2. Fujimori H, Shikanai M, Teraoka H, Masutani M, Yoshioka K. Induction of cancerous stem cells during embryonic stem cell differentiation. J Biol Chem. 2012; 287: 36777-91.
  3. Yoshioka K, Atsumi Y, Fukuda H, Masutani M, Teraoka H. The quiescent cellular state is Arf/p53-dependent and associated with H2AX downregulation and genome stability. Int J Mol Sci. 2012; 13: 6492-506.
  4. Hifumi Y, Fujii G, Takahashi M, Yamamoto M, Nakano K, Nakanishi R, Shimura M, Ishigamori R, Yanaka A, Mutoh M. Synergistic suppression of mice intestinal tumorigenesis by angiotensin II receptor blocker and metformin. Ulcer Res. 2012; 39: 201-6. Japanese
  5. Nakano K, Yamamoto M, Takahashi M, Fujii G, Hifumi Y, Shimura M, Nakanishi R, Komiya M, Yanaka A, Mutoh M. Effects of triglyceride on colon epithelial cells during colon carcinogenesis. Ulcer Res. 2012; 39: 196-200. Japanease
  6. Mutoh M, Fujii G, Yamamoto M, Takahashi M. Searching for effective colon cancer prevention methods targeting adipocytokines. Ulcer Res. 2012; 39: 80-4. Japanease
  7. Yoshimoto M, Hayakawa T, Mutoh M, Imai T, Tsuda K, Kimura S, Umeda IO, Fujii H, Wakabayashi K. In vivo SPECT imaging using 111In-DOTA-c(RGDfK) to detect early lesions in a hamster pancreatic carcinogenesis model. J Nucl Med. 2012; 53: 765-71.
  8. Hori M, Onaya H, Takahashi M, Hiraoka N, Mutoh M, Kosuge T, Nakagama H. Invasive ductal carcinoma developed in the pancreas with severe fatty infiltration. Pancreas 2012; 41: 1137-9.
  9. Ueno T, Teraoka N, Takasu S, Nakano K, Takahashi M, Yamamoto M, Fujii G, Komiya M, Yanaka A, Wakabayashi K, Mutoh M. Suppressive effect of pioglitazone, a PPAR　gamma ligand, on azoxymethane-induced colon aberrant crypt foci in KK-Ay mice. Asian Pac J Cancer Prev. 2012; 13: 4067-73.
  10. Shimura M, Yamamoto M, Fujii G, Takahashi M, Komiya M, Noma N, Tanuma S, Yanaka A, Mutoh M. Novel compound SK-1009 suppresses IL-6 expression through modulation of activation of NF-kappaB pathway. Biol Pharm Bull. 2012; 35: 2186-91.
  11. Ueno T, Imaida K, Yoshimoto M, Hayakawa T, Takahashi M, Imai T, Yanaka A, Tsuta K, Komiya M, Wakabayashi K, Mutoh M. Non-invasive X-ray micro-computed tomography evaluation of indomethacin on urethane-induced lung carcinogenesis in mice. Anticancer Res. 2012; 32: 4773-80.
  12. 武藤倫弘、藤井元、高橋真美。大腸がんとアディポサイトカイン、脂質異常。　The Lipid, 23(3): 82-89 (2012).
  13. 武藤倫弘、藤井元。分子スポーツ医学を利用したがん予防の可能性。週刊医学のあゆみ, 243: 694-700 (2012).

2013

  1. Ishino K, Mutoh M, Totsuka Y, Nakagama H. Metabolic syndrome: A novel high-risk state for colorectal cancer. Cancer Lett. 2013; 334(1): 56-61.
  2. Kato T, Totsuka Y, Hasei T, Watanabe T, Wakabayashi K, Kinae N, Masuda S, In vivo examination of the genotoxicity of the urban air and surface soil pollutant, 3,6-dinitrobenzo[e]pyrene, with intraperitoneal and intratracheal administration. Environ Toxicol. 2013; 28: 588-94.
  3. Nakano T, Matsushima-Hibiya Y, Yamamoto M, Takahashi-Nakaguchi A, Fukuda H, Ono M, Takamura-Enya T, Kinashi H, Totsuka Y. ADP-ribosylation of guanosine by SCO5461 protein secreted from Streptomyces coelicolor. Toxicon. 2013; 63: 55-63.
  4. Lin Y, Totsuka Y, He Y, Kikuchi S, Qiao Y, Ueda J, Wei W, Inoue M, Tanaka H. Comparative epidemiology of esophageal cancer between Japan and China. J Epidemiol. 2013; 23: 233-42.
  5. Kato T, Totsuka Y, Ishino K, Matsumoto Y, Tada Y, Nakae D, Goto S, Masuda S, Ogo S, Kawanishi M, Yagi T, Matsuda T, Watanabe M, Wakabayashi K. Genotoxicity of multi-walled carbon nanotubes in both in vitro and in vivo assay systems. Nanotoxicology 2013; 7: 452-61.
  6. Kawanishi M, Ogo S, Ikemoto M, Totsuka Y, Ishino K, Wakabayashi K, Yagi T. Genotoxicity and reactive oxygen species production induced by magnetite nanoparticles in mammalian cells. J Toxicol Sci. 2013; 38(3): 503-11.
  7. Takahashi-Nakaguchi A, Matsumoto Y, Yamamoto M, Iwabuchi K, Totsuka Y, Sugimura T, Wakabayashi K. Demonstration of cytotoxicity against wasps by Pierisin-1: A possible defense factor in the cabbage white butterfly. PLoS One 2013; 8(4): e60539.
  8. Watanabe M, Yoneda M, Morohashi A, Hori Y, Okamoto D, Sato A, Kurioka D, Nittami T, Hirokawa Y, Shiraishi T, Kawai K, Kasai H, Totsuka Y. Effects of Fe3O4 magnetic nanoparticles on A549 cells. Int J Mol Sci. 2013; 14: 15546-60.
  9. Osawa T, Atsumi Y, Sugihara E, Saya H, Kanno M, Tashiro F, Masutani M, Yoshioka K. Arf and p53 act as guardians of a quiescent cellular state by protecting against immortalization of cells with stable genomes. Biochem Biophys Res Comm. 2013; 432: 34-9.
  10. Atsumi Y, Inase A, Osawa T, Sugihara E, Sakasai R, Fujimori H, Teraoka H, Saya H, Kanno M, Tashiro F, Nakagama H, Masutani M, Yoshioka K. Arf/p53 module, which induces apoptosis, downregulates histone H2AX to allow normal cells to survive in the presence of anti-cancer drugs. J Biol Chem. 2013; 288: 13269-77.
  11. Ishikawa H, Wakabayashi K, Suzuki S, Mutoh M, Hirata K, Nakamura T, Takeyama I, Kawano A, Gondo N, Abe T, Tokudome S, Goto C, Matsuura N, Sakai T. Preventive effects of low-dose aspirin on colorectal adenoma growth in patients with familial adenomatous polyposis: Double-blind, randomized clinical study. Cancer Med. 2013; 2: 50-6.
  12. Ishino K, Mutoh M, Totsuka Y, Nakagama H. Metabolic syndrome and colon carcinogenesis. Cancer letts (SpI; Technologies in Carcinogenesis). 2013; 334(1): 56-61.
  13. Takahashi M, Mutoh M, Ishigamori R, Fujii G, Imai T. Involvement of inflammatory factors in pancreatic carcinogenesis and preventive effects of anti-inflammatory agents. Semin in Immunopathol. 2013; 35: 203-27.
  14. Arai Y, Totoki Y, Nakamura H, Hama N, Kohno T, Tsuta K, Yoshida A, Asamura H, Mutoh M, Takahashi H, Tatsuno K, Hosoda F, Tsuda H, Aburatani H, Miyano S, Shibata T. Mouse model for ROS-1-rearranged lung cancer. PLoS One 2013; 8: e56010.
  15. Fujimoto K, Fujii G, Mutoh M, Mochida Y, Tanaka H, Wada M. Suppression of intestinal polyp development through inhibition of P-glycoprotein by verapamil in ApcMin/+ mice. Eur J Cancer Prev. 2013; 22: 8-10.
  16. Iimuro M, Arakawa T, Matsumoto T, Wakabayashi K, Mutoh M. Effects of dietary calcium on Helicobacter pylori-induced gastritis in Mongolian gerbils. Anticancer Res 2013; 33: 3667-74.
  17. Hayakawa T, Mutoh M, Imai T, Tsuta K, Yanaka A, Fujii H, Yoshimoto M. SPECT imaging using 111In-DOTA-c(RGDfK) to detect nodules in a mouse lung carcinogenesis model. Ann Nucl Med. 2013; 27: 640-7.
  18. Ito K, Ishigamori R, Mutoh M, Ohta T, Imai T, Takahashi M. Ay Allele promotes azoxymethane-induced colorectal carcinogenesis via macrophage migration in hyperlipidemic/diabetic KK mice. Cancer Sci. 2013; 104: 835-43.
  19. Komiya M, Fujii G, Takahashi M, Iigo M, Mutoh M. Prevention and intervention trials for colorectal cancer. Japanese J Clin Oncol. 2013; 43: 685-94.
  20. Miyanaga A, Honda K, Tsuta K, Masuda M, Yamaguchi U, Fujii G, Miyamoto A, Shinagawa S, Miura N, Tsuda H, Sakuma T, Asamura H, Gemma A, Yamada T. Diagnostic and prognostic significance of the alternatively spliced ACTN4 variant in high-grade neuroendocrine pulmonary tumours. Ann Oncol. 2013; 24: 84-90.
  21. 武藤倫弘、藤井元。アディポネクチンと大腸がん。　分子消化器病, 10(4):52-57 (2013).

2014

  1. Totsuka Y, Watanabe T, Coulibaly S, Kobayashi S, Nishizaki M, Okazaki M, Hasei T, Wakabayashi K, Nakagama H. In vivo genotoxicity of a novel heterocyclic amine, aminobenzoazepinoquinolinone-derivative (ABAQ), produced by the Maillard reaction between glucose and l-tryptophan. Mutat Res. 2014; 760: 48-55.
  2. Totsuka Y, Ishino K, Kato T, Goto S, Tada Y, Nakae D, Watanabe M, Wakabayashi K. Magnetite nanoparticles induce genotoxicity in the lung of mice via inflammatory response. Nanomaterials 2014; 4: 175-88.
  3. Kochi T, Shimizu M, Totsuka Y, Shirakami Y, Nakanishi T, Watanabe T, Tanaka T, Nakagama H, Wakabayashi K, Moriwaki H. A novel aromatic mutagen, 5-amino-6-hydroxy-8H-benzo[6,7]azepino[5,4,3-de]quinolin-7-one (ABAQ), induces colonic preneoplastic lesions in mice. Toxicology Reports 2014; 1: 69-73.
  4. Iwasaki M, Mukai T, Takachi R, Ishihara J, Totsuka Y, Tsugane S. Validity of a self-administered food frequency questionnaire in the estimation of heterocyclic aromatic amines. Cancer Causes Control. 2014; 25(8): 1015-28.
  5. Goto M, Shinmura K, Matsushima Y, Ishino K, Yamada H, Totsuka Y, Matsuda T, Nakagama H, Sugimura H. Human DNA glycosylase enzyme TDG repairs thymine mispaired with exocyclic etheno-DNA adducts. Free Radic Biol Med. 2014; 76: 136-46.
  6. Shimizu S, Fujii G, Takahashi M, Nakanaishi R, Komiya M, Shimura M, Noma N, Onuma W, Terasaki M, Yano T, Mutoh M. Sesamol suppresses cyclooxygenase-2 transcriptional activity in colon cancer cells and modifies intestinal polyp development in ApcMin/+ mice. J Clin Biochem Nutr. 2014; 54: 95-101.
  7. Komiya M, Fujii G, Takahashi M, Shimura M, Noma N, Shimizu S, Onuma W, Mutoh M. Bi-directional regulation between adiponectin and plasminogen activator-inhibitor-1 in 3T3-L1 cells. IN VIVO 2014; 28: 13-9.
  8. Hori M, Takahashi M, Hiraoka N, Yamaji T, Mutoh M, Ishigamori R, Furuta K, Okusaka T, Shimada K, Kosuge T, Kanai Y, Nakagama H. Pancreatic fatty infiltration serves as a risk factor for pancreatic cancer, independently of obesity and diabetes. Clin Transl Gastroenterol. 2014; 5: e53.
  9. Ishikawa H, Mutoh M, Suzuki S, Tokudome S, Saida Y, Abe T, Okamura S, Tajika M, Joh T, Tanaka S, Kudo S, Matsuda T, Iimuro M, Yukawa T, Takayama T, Sato Y, Lee K, Kitamura S, Mizuno M, Sano Y, Gondo N, Sugimoto K, Kusunoki M, Goto C, Matsuura N, Sakai T, Wakabayashi K. The preventive effects of low-dose enteric-coated aspirin tablets on development of colorectal tumor in Asian patients. GUT 2014; 63: 1755-9.
  10. Mutoh M, Fujii G. Potential of drug repositioning for colorectal cancer prevention: Inhibition of colorectal polyp recurrence by aspirin. BioIndustry, 2014; 31: 29-34. Japanese
  11. Terasaki M, Mutoh M, Fujii G, Takahashi M, Ishigamori R, Masuda S. Potential ability of xanthophylls to prevent obesity-associated cancer. World J Pharmacol. 2014; 3(4): 140-52.
  12. Mutoh M, Takahashi M and Wakabayashi K. "Cancer and Inflammation Mechanisms: Chemical, Biological, and Clinical Aspects", First edition. Chapter 20 ”Chemoprevention of colorectal cancer by anti-inflammatory agents”. Edited by Shosuke Kawanishi and Hiroshi Ohshima. Published 2014 by John Wiley & Sons, Inc.

2015

  1. Ishino K, Kato T, Kato M, Shibata T, Watanabe M, Wakabayashi K, Nakagama H, Totsuka Y. Comprehensive DNA adduct analysis reveals pulmonary inflammatory response contributes to genotoxic action of magnetite nanoparticles. Int J Mol Sci. 2015; 16(2): 3474-92.
  2. Yoshioka K, Atsumi Y, Nakagama H, Teraoka H. Development of cancer-initiating cells and immortalized cells with genomic instability. World J Stem Cells 2015; 7: 483-9.
  3. Fujimoto K, Fujii G, Sakurai H, Yoshitome H, Mutoh M, Wada M. Intestinal Peyer’s patches prevent tumorigenesis in ApcMin/+ mice. J Clin Biochem Nutr. 2015; 56: 43-8.
  4. Shimizu S, Ishigamori R, Fujii G, Takahashi M, Onuma W, Terasaki M, Yano T, Mutoh M. Involvement of NADPH oxidases in suppression of cyclooxygenase-2 promoter-dependent transcriptional activities by sesamol. J Clin Biochem Nutr. 2015; 56: 118-22.
  5. Mutoh M, Fujii G, Miyamoto S, Nakanishi R, Miura A, Sasazuki S. Colorectal cancer prevention by the way of drug repositioning. Ulcer Res. 2015; 42: 5-11. Japanese.
  6. 谷中昭典、武藤倫弘。低線量放射線の長期暴露がマウス大腸化学発がんに及ぼす影響。潰瘍, 42:48-50 (2015).
  7. Mutoh M, Ishikawa H, Wakabayahsi K. Colorectal cancer chemoprevention: for the broad clinical use in the future. Gan To Kagaku Ryoho. 2015; 42: 534-537. Japanese.
  8. Mutoh M, Ishikawa H. Effects of smoking on cancer prevention studies. Cancer Prev Res (Phila). 2015; 8: 760.
  9. Shimizu S, Miyamoto S, Fujii G, Nakanishi R, Onuma W, Ozaki Y, Fujimoto K, Yano T, Mutoh M. Suppression of intestinal carcinogenesis in Apc-mutant mice by limonin. J Clin Biochem Nutr. 2015; 57: 39-43.
  10. Fujimoto K, Fujii G, Taniguchi K, Yasuda K, Matsuo Y, Hashiyama A, Mutoh M, Tanaka H, Wada M, Involvement of trefoil factor family 2 in the enlargement of intestinal tumors in ApcMin/+ mice. Biochem Biophys Res Commun. 2015; 463: 859-63.
  11. Komiya M, Fujii G, Miyamoto S, Takahashi M, Ishigamori R, Onuma W, Ishino K, Totsuka Y, Fujimoto K, Mutoh M. Suppressive effects of the NADPH oxidase inhibitor apocynin on intestinal tumorigenesis in obese KK-Ay and Apc mutant Min mice. Cancer Sci. 2015; 106(11): 1499-505.
  12. Shiotani A, Ishikawa H, Mutoh M, Takeshita T, Nakamura T, Morimoto K, Sakai T, Wakabayashi K, Sakai T, Matuura N. Genetic polymorphisms in ADH1B and ALDH2 are associated with colorectal tumors in Japan. J Cancer Therapy 2015; 6(12): 1054-62.
  13. Miyamoto S, Fujii G, Komiya M, Terasaki M and Mutoh M. “Critical Dietary Factors in Cancer Chemoprevention”. First edition. Chaptor “Potential for sesame seed-derived factors to prevent colorectal cancer”, Edited by Aamir Ahmad and Mohammad Fahad Ullah Published 2015 by Springer Publishers (Basel, Switzerland).
  14. Atsumi Y, Minakawa Y, Ono M, Dobashi S, Shinohe K, Shinohara A, Takeda S, Takagi M, Takamatsu N, Nakagama H, Teraoka H, Yoshioka K. ATM and SIRT6/SNF2H mediate transient H2AX stabilization when DSBs form by blocking HUWE1 to allow efficient γH2AX foci formation. Cell Reports 2015; 13: 2728-40.

2016

  1. Hamoya T, Fujii G, Miyamoto S, Takahashi M, Totsuka Y, Wakabayashi K, Toshima J, Mutoh M. Effects of NSAIDs on the risk factors of colorectal cancer: a mini review. Genes Environ. 2016; 38: 6.
  2. Minakawa Y, Atsumi Y, Shinohara A, Murakami Y, Teraoka H, Yoshioka K. Gamma-irradiated quiescent cells repair directly induced double-strand breaks but accumulate persistent double-strand breaks during subsequent DNA replication. Genes Cells. 2016; 21: 789-97.
  3. Mimaki S, Totsuka Y, Suzuki Y, Nakai C, Goto M, Kojima M, Arakawa H, Takemura S, Tanaka S, Marubashi S, Matsuda T, Shibata T, Nakagama H, Ochiai A, Kubo S, Esumi H, a Tsuchihara K. Hypermutation and unique mutational signatures of occupational cholangiocarcinoma in printing workers exposed to haloalkanes. Carcinogenesis 2016; 37(8): 817-26.
  4. Nakamura T, Ishikawa H, Mutoh M, Wakabayashi K, Kawano A, Sakai T, Matuura N. Coffee prevents the proximal colorectal adenomas in Japanese men: A prospective cohort study. Eur J Cancer Prev. 2016; 25(5): 388-94.
  5. Ishikawa H, Mutoh M, Iwama T, Suzuki S, Abe T, Takeuchi Y, Nakamura T, Ezoe Y, Fujii G, Nakajima T, Wakabayashi K, Sakai T. Colorectal cancer prevention using endoscopic polypectomy in familial adenomatous polyposis (a retrospective study). Endoscopy 2016; 48(1): 51-5.
  6. Hori M, Mutoh M, Imai T, Nakagama H, Takahashi M. Possible involvement of pancreatic fatty infiltration in pancreatic carcinogenesis. Journal of Pancreas, in press
  7. Imaoka T, Nishimura M, Daino K, Morioka T, Nishimura Y, Uemura H, Akimoto K, Furukawa Y, Fukushi M, Wakabayashi K, Mutoh M, ShimadaY. A rat model to study the effects of diet-induced obesity on radiation-induced mammary carcinogenesis. Radiat Res. 2016; 185(5): 505-15.
  8. Onuma W, Tomono S, Shinngo M, Fujii G, Hamoya T, Fujimoto K, Miyoshi N, Fukai F, Wakabayashi K, Mutoh M. Irsogladine maleate, a gastric mucosal protectant, suppresses intestinal polyp development in Apc-mutant mice. Oncotarget. 2016; 7(8): 8640-52.
  9. 宮本真吾、石川秀樹、武藤倫弘、若林敬二、酒井敏行。低用量アスピリンによる大腸発がん予防。日本血栓止血学会誌, 27(1): 29-33（2016年2月号）.
  10. 武藤倫弘、藤井元、宮本真吾。大腸がん化学予防の現状と将来。日本消化器病学会雑誌, 113(7): 1186-90（2016年7月号）.
  11. Hori M, Onaya H, Hiraoka N, Takahashi　M, Mutoh M, Shimada　K, Nakagama H. Evaluation of the degree of pancreatic fatty infiltration by area-based assessment on CT images: comparison with histopathology-based and CT attenuation index-based assessments. Jpn J Radiol. 2016; 34(10): 667-76.
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