Masayuki Yamaguchi, MD, PhDMasayuki Yamaguchi, MD, PhD

 

We are intensively studying MR imaging techniques to visualize the morphological changes of cancer lesions by using various animal models and a 9.4 tesla ultra-high field MR scanner. The MR scanner can acquire very high-resolution MR images (approximately 70 micron in pixel size), thereby detecting tiny changes in cancer lesions. Moreover, MR imaging is definitely non-invasive technique, so you can actually observe the interior of experimental cancer lesions non-destructively and longitudinally during a long period.

Official title

• Section Head, Division of Functional Imaging

Area of research

• Diagnostic Radiology, Magnetic Resonance Imaging & Spectroscopy

Keywords

• MRI (Magnetic Resonance Imaging)
• Artificial Intelligence

Current main research theme

• In vivo MRI and MRS of cancer animal models by using a 9.4 tesla Bruker scanner
• MR imaging of the seminiferous tubules

Collaborative research themes

• Scientists who are interested in MR imaging and spectroscopy

Email 

masyamag●east.ncc.go.jp（● repalce to @）

略歴 

Education

• 1996  University of Tsukuba, School of Medicine (Medical Doctor)
• 2006  University of Tsukuba, Graduate School of Comprehensive Human Sciences (PhD, Medical Science)

Supervisors; Dr. Mitsumori (National Institute for Environmental Studies, Tsukuba, Japan), Professors Itai and Minami (Dept. of Radiology, University of Tsukuba)

Dissertation (in Japanese): In vivo assessment of spermatogenesis by using magnetic resonance imaging and spectroscopy.

Work history

• National Cancer Center, Kashiwa, Japan
  2007-Present: Section head, Division of Functional Imaging
• Tsukuba Gakuen Hospital, Tsukuba, Japan
  2006-2007, Department of Clinical Radiology
• University of Tsukuba Hospital, Tsukuba, Japan
  1996-2002, Department of Radiology (Residency)

Major affiliated societies

• Japanese Society for Magnetic Resonance in Medicine (JSMRM)
• Japan Radiological Society (JRS)
• International Society for Magnetic Resonance in Medicine (ISMRM)

Publications

1. Nagai M, Yamaguchi M, Mori K, Furuta T, Ashino H, Kurosawa H, Kasahara H, Minami M, Fujii H Magnetic resonance-based visualization of thermal ablative margins around hepatic tumors by means of systemic ferucarbotran administration before radiofrequency ablation: animal study to reveal the connection between excess iron deposition and T2*-weighted hypointensity in ablative margins. Invest Radiol. 2015 Jun;50(6):376-83.
2. Yamaguchi M, Mitsuda M, Ezawa K, Nakagami R, Furuta T, Sekine N, Niitsu M, Fujii H. Artifact-reduced simultaneous MRI of multiple rats with liver cancer using PROPELLER. J Magn Reson Imaging, 2013 Jul;38(1):225-30
3. Kutsuna N, Higaki T, Matsunaga S, Otsuki T, Yamaguchi M, Fujii H, Hasezawa S. Active learning framework with iterative clustering for bioimage classification. Nat Commun, 3:1032, 2012
4. Yamaguchi M, Mitsumori F, Watanabe H, Takaya N, Minami M. Visualization of seminiferous tubules in rat testes in normal and diseased conditions by high-resolution MRI. Magn Reson Med. 62:637-644, 2009
5. Yamaguchi M, Mitsumori F, Watanabe H, Takaya N, Minami M. In vivo localized 1H MR spectroscopy of rat testes: stimulated echo acquisition mode (STEAM) combined with short TI inversion recovery (STIR) improves the detection of metabolite signals. Magn Reson Med. 55: 749-754, 2006

Visit PubMed for a listing of publications.