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Publications

2021年

  1. NEW Yoh K, Matsumoto S, Furuya N, Nishino K, Miyamoto S, Oizumi S, Okamoto N, Itani H, Kuyama S, Nakamura A, Nishi K, Fukuda I, Tsuta K, Hayashi Y, Motoi N, Ishii G, Goto K. Comprehensive assessment of PD-L1 expression, tumor mutational burden and oncogenic driver alterations in non-small cell lung cancer patients treated with immune checkpoint inhibitors. Lung Cancer. 2021 Sep;159:128-134.
  2. NEW Oiwa H, Aokage K, Suzuki A, Sato K, Kuroe T, Mimaki S, Tane K, Miyoshi T, Samejima J, Tsuchihara K, Goto K, Funai K, Tsuboi M, Nakai T, Ishii G. Clinicopathological, gene expression and genetic features of stage I lung adenocarcinoma with necrosis. Lung Cancer. 2021 Sep;159:74-83.
  3. Nakasone S, Suzuki A, Okazaki H, Onodera K, Zenkoh J, Ishii G, Suzuki Y, Tsuboi M, Tsuchihara K. Predictive markers based on transcriptome modules for vinorelbine-based adjuvant chemotherapy for lung adenocarcinoma patients. Lung Cancer. 158:115-125, 2021
  4. Tane K, Miyoshi T, Samejima J, Aokage K, Ishii G, Tsuboi M. Lymph node metastasis and predictive factors in clinical stage IA squamous cell carcinoma of the lung based on radiological findings. Gen Thorac Cardiovasc Surg. 2021 Online ahead of print.
  5. Hoshino H, Aokage K, Miyoshi T, Tane K, Kojima M, Sugano M, Kuwata T, Ochiai A, Suzuki K, Tsuboi M, Ishii G. Correlation between the number of viable tumor cells and immune cells in the tumor microenvironment in non-small cell lung cancer after induction therapy. Pathol Int. 2021 Online ahead of print.
  6. Katsumata S, Tane K, Suzuki J, Miyoshi T, Samejima J, Aokage K, Ishii G, Tsuboi M. Mediastinal lymph node dissection for the elderly with clinical stage I non-small cell lung cancer. Gen Thorac Cardiovasc Surg. 2021 Online ahead of print.
  7. Sugimoto A, Umemura S, Miyoshi T, Nakai T, Kuroe T, Nosaki K, Ikeda T, Udagawa H, Kirita K, Zenke Y, Matsumoto S, Yoh K, Niho S, Tsuboi M, Goto K, Ishii G. High proportion of tumor necrosis predicts poor survival in surgically resected high-grade neuroendocrine carcinoma of the lung. Lung Cancer. 157:1-8, 2021
  8. Komine R, Kojima M, Ishii G, Kudo M, Sugimoto M, Kobayashi S, Takahashi S, Konishi M, Kobayashi T, Akimoto T, Murakami A, Sasaki M, Tanaka M, Matsuzaki A, Ohike N, Uchida K, Sugiyama T, Hirabayashi K, Tajiri T, Ishida K, Kai K, Omori Y, Notohara K, Yamaguchi H, Matsuda Y, Naito Y, Fukumura Y, Hamada Y, Mihara Y, Masugi Y, Gotohda N, Harada K, Fukushima N, Furukawa T. Recognition and pathological features of periampullary region adenocarcinoma with an indeterminable origin. Cancer Med. 2021 Online ahead of print.
  9. Okubo S, Suzuki T, Hioki M, Shimizu Y, Toyama H, Morinaga S, Gotohda N, Uesaka K, Ishii G, Takahashi S, Kojima M. The immunological impact of preoperative chemoradiotherapy on the tumor microenvironment of pancreatic cancer. Cancer Sci. 2021 Online ahead of print.
  10. Terao T, Yuda J, Yamauchi N, Guo YM, Shimada K, Sugano M, Ishii G, Minami Y. Brentuximab vedotin maintenance after autologous stem cell transplantation for refractory gray zone lymphoma with long-term remission. Mol Clin Oncol. 14(6):125, 2021
  11. Kudo M, Kobayashi S, Kojima M, Kobayashi T, Sugimoto M, Takahashi S, Konishi M, Ishii G, Gotohda N. Impact of previous history of choledochojejunostomy on the incidence of organ/space surgical site infection after hepatectomy. Asian J Surg. 2021 Online ahead of print.
  12. Ishii T, Suzuki A, Kuwata T, Hisamitsu S, Hashimoto H, Ohara Y, Yanagihara K, Mitsunaga S, Yoshino T, Kinoshita T, Ochiai A, Shitara K, Ishii G. Drug-exposed cancer-associated fibroblasts facilitate gastric cancer cell progression following chemotherapy. Gastric Cancer. 2021 Online ahead of print.
  13. Nomura K, Aokage K, Nakai T, Sakashita S, Miyoshi T, Tane K, Samejima J, Suzuki K, Tsuboi M, Ishii G. Prognostic impact of extranodal extension in patients with pN1-N2 lung adenocarcinoma. J Cancer Res Clin Oncol. 2021 Online ahead of print.
  14. Shiraishi T, Ikeda K, Tsukada Y, Nishizawa Y, Sasaki T, Ito M, Kojima M, Ishii G, Tsumura R, Saijou S, Koga Y, Yasunaga M, Matsumura Y. High expression of TMEM180, a novel tumour marker, is associated with poor survival in stage III colorectal cancer. BMC Cancer. 21(1):302, 2021
  15. Katsumata S, Aokage K, Ishii G, Hoshino H, Suzuki J, Miyoshi T, Tane K, Samejima J, Tsuboi M. Pathological features and prognostic implications of ground-glass opacity components on computed tomography for clinical stage I lung adenocarcinoma. Surg Today. 2021 Online ahead of print.
  16. Morisue R, Kojima M, Suzuki T, Nakatsura T, Ojima H, Watanabe R, Sugimoto M, Kobayashi S, Takahashi S, Konishi M, Ishii G, Gotohda N, Fujiwara T, Ochiai A. Sarcomatoid hepatocellular carcinoma is distinct from ordinary hepatocellular carcinoma: Clinicopathologic, transcriptomic and immunologic analyses. Int J Cancer. 2021 Online ahead of print.
  17. Kuroe T, Watanabe R, Kojima M, Morisue R, Sugano M, Kuwata T, Masuda H, Kusuhara S, Matsubara N, Oda S, Ushiku T, Ishii G. Evaluation of the morphological features and unfavorable prognostic impact of dirty necrosis in renal cell carcinoma. J Cancer Res Clin Oncol. 2021 Online ahead of print.
  18. Amemiya R, Miyoshi T, Aokage K, Suzuki J, Hoshino H, Udagawa H, Tane K, Sugano M, Kojima M, Fujii S, Kuwata T, Ochiai A, Goto K, Ikeda N, Tsuboi M, Ishii G. Prognostic impact of the tumor immune microenvironment in pulmonary pleomorphic carcinoma. Lung Cancer, 153:56-65, 2021
  19. Sekihara K, Aokage K, Hiyama T, Oiwa H, Miyoshi T, Tane K, Ishii G, Tsuboi M. Prognostic impact of home oxygen therapy on patients with resected non-small-cell lung cancer with interstitial lung disease. Surg Today. 2021 Online ahead of print.
  20. Suzuki J, Aokage K, Neri S, Sakai T, Hashimoto H, Su Y, Yamazaki S, Nakamura H, Tane K, Miyoshi T, Sugano M, Kojima M, Fujii S, Kuwata T, Ochiai A, Tsuboi M, Ishii G. Relationship between podoplanin-expressing cancer-associated fibroblasts and the immune microenvironment of early lung squamous cell carcinoma. Lung Cancer. 153:1-10, 2021

2020年

  1. Mpekris F, Panagi M, Voutouri C, Martin JD, Samuel R, Takahashi S, Gotohda N, Suzuki T, Papageorgis P, Demetriou P, Pierides C, Koumas L, Costeas P, Kojima M, Ishii G, Constantinidou A, Kataoka K, Cabral H, Stylianopoulos T. Normalizing the Microenvironment Overcomes Vessel Compression and Resistance to Nano-immunotherapy in Breast Cancer Lung Metastasis. Adv Sci (Weinh). 8(3):2001917, 2020
  2. Su Y, Yamazaki S, Morisue R, Suzuki J, Yoshikawa T, Nakatsura T, Tsuboi M, Ochiai A, Ishii G. Tumor-Infiltrating T Cells Concurrently Overexpress CD200R with Immune Checkpoints PD-1, CTLA-4, and TIM-3 in Non-Small-Cell Lung Cancer. Pathobiology, 15:1-10, 2020
  3. Su Y, Yamazaki S, Morisue R, Suzuki J, Yoshikawa T, Nakatsura T, Tsuboi M, Ochiai A, Ishii G. Tumor-Infiltrating T Cells Concurrently Overexpress CD200R with Immune Checkpoints PD-1, CTLA-4, and TIM-3 in Non-Small-Cell Lung Cancer. Pathobiology, 15:1-10, 2020
  4. Kenmotsu H, Niho S, Tsuboi M, Wakabayashi M, Ishii G, Nakagawa K, Daga H, Tanaka H, Saito H, Aokage K, Takahashi T, Menju T, Kasai T, Yoshino I, Minato K, Okada M, Eba J, Asamura H, Ohe Y, Watanabe SI. Randomized Phase III Study of Irinotecan Plus Cisplatin Versus Etoposide Plus Cisplatin for Completely Resected High-Grade Neuroendocrine Carcinoma of the Lung: JCOG1205月12日06. J Clin Oncol. 38(36):4292-4301, 2020
  5. Sakai T, Udagawa H, Matsumoto S, Yoh K, Nosaki K, Ikeda T, Zenke Y, Kirita K, Niho S, Akimoto T, Goto K, Ishii G. Morphological, immune and genetic features in biopsy sample associated with the efficacy of pembrolizumab in patients with non-squamous non-small cell lung cancer. J Cancer Res Clin Oncol. 2020 Online ahead of print.
  6. Kumagai S, Togashi Y, Kamada T, Sugiyama E, Nishinakamura H, Takeuchi Y, Vitaly K, Itahashi K, Maeda Y, Matsui S, Shibahara T, Yamashita Y, Irie T, Tsuge A, Fukuoka S, Kawazoe A, Udagawa H, Kirita K, Aokage K, Ishii G, Kuwata T, Nakama K, Kawazu M, Ueno T, Yamazaki N, Goto K, Tsuboi M, Mano H, Doi T, Shitara K, Nishikawa H. The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies. Nat Immunol. 21(11):1346-1358, 2020
  7. Ishii G, Ishii T. Review of cancer-associated fibroblasts and their microenvironment in post-chemotherapy recurrence. Hum Cell, 33(4):938-945, 2020
  8. Koike Y, Aokage K, Ikeda K, Nakai T, Tane K, Miyoshi T, Sugano M, Kojima M, Fujii S, Kuwata T, Ochiai A, Tanaka T, Suzuki K, Tsuboi M, Ishii G. Machine learning-based histological classification that predicts recurrence of peripheral lung squamous cell carcinoma. Lung Cancer, 147:252-258, 2020
  9. Ishii T, Kawazoe A, Sasaki A, Mishima S, Kentaro S, Nakamura Y, Kotani D, Kuboki Y, Taniguchi H, Kojima T, Doi T, Yoshino T, Kuwata T, Ishii G, Shitara K. Clinical and molecular factors for selection of nivolumab or irinotecan as third-line treatment for advanced gastric cancer. Ther Adv Med Oncol. 12:1758835920942377, 2020
  10. Sato K, Mimaki S, Yamashita R, Togashi Y, Naito T, Udagawa H, Katsumata S,
    Nakasone S, Miyoshi T, Tane K, Aokage K, Sugano M, Kojima M, Fujii S, Kuwata T,
    Ochiai A, Goto K, Tsuboi M, Tsuchihara K, Ishii G. Association between the
    mutational smoking signature and the immune microenvironment in lung
    adenocarcinoma. Lung Cancer, 147:12-20, 2020
  11. Inaba A, Hori K, Yoda Y, Ikematsu H, Takano H, Matsuzaki H, Watanabe Y,
    Takeshita N, Tomioka T, Ishii G, Fujii S, Hayashi R, Yano T. Artificial
    intelligence system for detecting superficial laryngopharyngeal cancer with high
    efficiency of deep learning. Head Neck, 42(9):2581-2592, 2020
  12. Udagawa H, Kirita K, Naito T, Nomura S, Ishibashi M, Matsuzawa R, Hisakane K,
    Usui Y, Matsumoto S, Yoh K, Niho S, Ishii G, Goto K. Feasibility and utility of
    transbronchial cryobiopsy in precision medicine for lung cancer: Prospective
    single-arm study. Cancer Sci, 111(7):2488-2498, 2020
  13. Kudo M, Kobayashi T, Gotohda N, Konishi M, Takahashi S, Kobayashi S, Sugimoto
    M, Okubo S, Martin J, Cabral H, Ishii G, Kojima M. Clinical Utility of
    Histological and Radiological Evaluations of Tumor Necrosis for Predicting
    Prognosis in Pancreatic Cancer. Pancreas, 49(5):634-641, 2020
  14. Yamazaki S, Su Y, Maruyama A, Makinoshima H, Suzuki J, Tsuboi M, Goto K,
    Ochiai A, Ishii G. Uptake of collagen type I via macropinocytosis cause mTOR
    activation and anti-cancer drug resistance. Biochem Biophys Res Commun,
    526(1):191-198, 2020
  15. Kubota Y, Kawazoe A, Sasaki A, Mishima S, Sawada K, Nakamura Y, Kotani D,
    Kuboki Y, Taniguchi H, Kojima T, Doi T, Yoshino T, Ishii G, Kuwata T, Shitara K.
    The Impact of Molecular Subtype on Efficacy of Chemotherapy and Checkpoint
    Inhibition in Advanced Gastric Cancer. Clin Cancer Res, 26(14):3784-3790, 2020
  16. Sekihara K, Aokage K, Miyoshi T, Tane K, Ishii G, Tsuboi M. Perioperative
    pirfenidone treatment as prophylaxis against acute exacerbation of idiopathic
    pulmonary fibrosis: a single-center analysis. Surg Today, 50(8):905-911, 2020
  17. Oki T, Aokage K, Nomura S, Tane K, Miyoshi T, Shiiya N, Funai K, Tsuboi M,
    Ishii G. Optimal method for measuring invasive size that predicts survival in
    invasive mucinous adenocarcinoma of the lung. J Cancer Res Clin Oncol,
    146(5):1291-1298, 2020
  18. Miyashita T, Neri S, Hashimoto H, Akutsu A, Sugano M, Fujii S, Ochiai A,
    Ishii G. Fibroblasts-dependent invasion of podoplanin-positive cancer stem cells
    in squamous cell carcinoma. J Cell Physiol, 235(10):7251-7260, 2020
  19. Kakinuma R, Muramatsu Y, Asamura H, Watanabe SI, Kusumoto M, Tsuchida T,
    Kaneko M, Tsuta K, Maeshima AM, Ishii G, Nagai K, Yamaji T, Matsuda T, Moriyama
    N. Low-dose CT lung cancer screening in never-smokers and smokers: results of an
    eight-year observational study. Transl Lung Cancer Res, 9(1):10-22, 2020
  20. Sugiyama E, Togashi Y, Takeuchi Y, Shinya S, Tada Y, Kataoka K, Tane K, Sato
    E, Ishii G, Goto K, Shintani Y, Okumura M, Tsuboi M, Nishikawa H. Blockade of
    EGFR improves responsiveness to PD-1 blockade in <i>EGFR</i>-mutated non-small
    cell lung cancer. Sci Immunol, 5(43):eaav3937, 2020
  21. Maeda M, Takeshima H, Iida N, Hattori N, Yamashita S, Moro H, Yasukawa Y,
    Nishiyama K, Hashimoto T, Sekine S, Ishii G, Ochiai A, Fukagawa T, Katai H,
    Sakai Y, Ushijima T. Cancer cell niche factors secreted from cancer-associated
    fibroblast by loss of H3K27me3. Gut, 69(2):243-251, 2020

2019年

  1. Okubo S, Kojima M, Matsuda Y, Hioki M, Shimizu Y, Toyama H, Morinaga S,
    Gotohda N, Uesaka K, Ishii G, Mino-Kenudson M, Takahashi S. Area of residual
    tumor (ART) can predict prognosis after post neoadjuvant therapy resection for
    pancreatic ductal adenocarcinoma. Sci Rep, 9(1):17145, 2019
  2. Naito T, Udagawa H, Umemura S, Sakai T, Zenke Y, Kirita K, Matsumoto S, Yoh
    K, Niho S, Tsuboi M, Ishii G, Goto K. Non-small cell lung cancer with loss of
    expression of the SWI/SNF complex is associated with aggressive
    clinicopathological features, PD-L1-positive status, and high tumor mutation
    burden. Lung Cancer, 138:35-42, 2019
  3. Maishi N, Kikuchi H, Sato M, Nagao-Kitamoto H, Annan DA, Baba S, Hojo T,
    Yanagiya M, Ohba Y, Ishii G, Masutomi K, Shinohara N, Hida Y, Hida K.
    Development of Immortalized Human Tumor Endothelial Cells from Renal Cancer. Int
    J Mol Sci, 20(18):4595, 2019
  4. Ota T, Kirita K, Matsuzawa R, Udagawa H, Matsumoto S, Yoh K, Niho S, Ishii
    G, Goto K. Validity of using immunohistochemistry to predict treatment outcome
    in patients with non-small cell lung cancer not otherwise specified. J Cancer
    Res Clin Oncol, 145(10):2495-2506, 2019
  5. Oki T, Aokage K, Ueda T, Sugano M, Tane K, Miyoshi T, Kojima M, Fujii S,
    Kuwata T, Ochiai A, Funai K, Tsuboi M, Ishii G. Proportion of goblet cell is
    associated with malignant potential in invasive mucinous adenocarcinoma of the
    lung. Pathol Int, 69(9):526-535, 2019
  6. Hisamitsu S, Miyashita T, Hashimoto H, Neri S, Sugano M, Nakamura H,
    Yamazaki S, Ochiai A, Goto K, Tsuboi M, Ishii G. Interaction between cancer
    cells and cancer-associated fibroblasts after cisplatin treatment promotes
    cancer cell regrowth. Hum Cell, 32(4):453-464, 2019
  7. Ota T, Niho S, Kirita K, Ishii G, Tsuboi M, Goto K. Impressive response to
    nivolumab of non-small-cell lung cancer containing sarcomatoid components.
    Respirol Case Rep, 7(8):e00477, 2019
  8. Ichikawa T, Aokage K, Miyoshi T, Tane K, Suzuki K, Makinoshima H, Tsuboi M,
    Ishii G. Correlation between maximum standardized uptake values on FDG-PET and
    microenvironmental factors in patients with clinical stage IA radiologic pure-
    solid lung adenocarcinoma. Lung Cancer, 136:57-64, 2019
  9. Suzuki E, Yamazaki S, Naito T, Hashimoto H, Okubo S, Udagawa H, Goto K,
    Tsuboi M, Ochiai A, Ishii G. Secretion of high amounts of hepatocyte growth
    factor is a characteristic feature of cancer-associated fibroblasts with EGFR-
    TKI resistance-promoting phenotype: A study of 18 cases of cancer-associated
    fibroblasts. Pathol Int, 69(8):472-480, 2019
  10. Sakai T, Miyoshi T, Umemura S, Suzuki J, Nakasone S, Okada S, Tane K, Aokage
    K, Goto K, Motoi N, Ishii G, Tsuboi M. Large pulmonary sclerosing pneumocytoma
    with massive necrosis and vascular invasion: a case report. Oxf Med Case
    Reports, 2019(7):omz066, 2019
  11. Naito T, Udagawa H, Sato J, Horinouchi H, Murakami S, Goto Y, Kanda S,
    Fujiwara Y, Yamamoto N, Zenke Y, Kirita K, Matsumoto S, Yoh K, Niho S, Motoi N,
    Ohe Y, Ishii G, Goto K. A Minimum of 100 Tumor Cells in a Single Biopsy Sample
    Is Required to Assess Programmed Cell Death Ligand 1 Expression in Predicting
    Patient Response to Nivolumab Treatment in Nonsquamous Non-Small Cell Lung
    Carcinoma. J Thorac Oncol. 14(10):1818-1827, 2019
  12. Martin JD, Panagi M, Wang C, Khan TT, Martin MR, Voutouri C, Toh K,
    Papageorgis P, Mpekris F, Polydorou C, Ishii G, Takahashi S, Gotohda N, Suzuki
    T, Wilhelm ME, Melo VA, Quader S, Norimatsu J, Lanning RM, Kojima M, Stuber MD,
    Stylianopoulos T, Kataoka K, Cabral H. Dexamethasone Increases Cisplatin-Loaded
    Nanocarrier Delivery and Efficacy in Metastatic Breast Cancer by Normalizing the
    Tumor Microenvironment. ACS Nano, 13(6):6396-6408, 2019
  13. Omori T, Aokage K, Nakamura H, Katsumata S, Miyoshi T, Sugano M, Kojima M,
    Fujii S, Kuwata T, Ochiai A, Ikeda N, Tsuboi M, Ishii G. Growth patterns of
    small peripheral squamous cell carcinoma of the lung and their impacts on
    pathological and biological characteristics of tumor cells. J Cancer Res Clin
    Oncol, 145(7):1773-1783, 2019
  14. Katsumata S, Aokage K, Ishii G, Nakasone S, Sakai T, Okada S, Miyoshi T,
    Tane K, Tsuboi M. Prognostic Impact of the Number of Metastatic Lymph Nodes on
    the Eighth Edition of the TNM Classification of NSCLC. J Thorac Oncol,
    14(8):1408-1418, 2019
  15. Oki T, Hishida T, Yoshida J, Goto M, Sekihara K, Miyoshi T, Aokage K, Ishii
    G, Tsuboi M. Survival and prognostic factors after pulmonary metastasectomy of
    head and neck cancer: what are the clinically informative prognostic indicators?
    Eur J Cardiothorac Surg, 55(5):942-947, 2019
  16. Naito T, Umemura S, Nakamura H, Zenke Y, Udagawa H, Kirita K, Matsumoto S,
    Yoh K, Niho S, Motoi N, Aokage K, Tsuboi M, Ishii G, Goto K. Successful
    treatment with nivolumab for SMARCA4-deficient non-small cell lung carcinoma
    with a high tumor mutation burden: A case report. Thorac Cancer,
    10(5):1285-1288, 2019
  17. Nakamura H, Sugano M, Miyashita T, Hashimoto H, Ochiai A, Suzuki K, Tsuboi
    M, Ishii G. Organoid culture containing cancer cells and stromal cells reveals
    that podoplanin-positive cancer-associated fibroblasts enhance proliferation of
    lung cancer cells. Lung Cancer. 134:100-107, 2019
  18. Miyoshi T, Aokage K, Katsumata S, Tane K, Ishii G, Tsuboi M. Ground-Glass
    Opacity Is a Strong Prognosticator for Pathologic Stage IA Lung Adenocarcinoma.
    Ann Thorac Surg, 108(1):249-255, 2019
  19. Miyoshi T, Yoshida J, Aokage K, Tane K, Ishii G, Tsuboi M. Stapling
    cartridge lavage cytology in limited resection for pulmonary malignant tumors:
    assessment of cytological status of the surgical margin. Heliyon, 5(2):e01240, 2019
  20. Suzuki J, Kojima M, Aokage K, Sakai T, Nakamura H, Ohara Y, Tane K, Miyoshi
    T, Sugano M, Fujii S, Kuwata T, Ochiai A, Ito M, Suzuki K, Tsuboi M, Ishii G.
    Clinicopathological characteristics associated with necrosis in pulmonary
    metastases from colorectal cancer. Virchows Arch, 474(5):569-575, 2019
  21. Kadota T, Seo S, Fuse H, Ishii G, Itoh K, Yano T, Kaneko K, Tsukasaki K.
    Complications and outcomes in diffuse large B-cell lymphoma with gastric lesions
    treated with R-CHOP. Cancer Med, 8(3):982-989, 2019
  22. Oono Y, Shinmura K, Hori K, Yoda Y, Ishii G, Ikematsu H, Yano T. Endoscopic
    submucosal resection using a ligation device without injection for duodenal
    neuroendocrine tumors. Surg Endosc, 33(6):2008-2014, 2019
  23. Miyashita T, Omori T, Nakamura H, Sugano M, Neri S, Fujii S, Hashimoto H,
    Tsuboi M, Ochiai A, Ishii G. Spatiotemporal characteristics of fibroblasts-
    dependent cancer cell invasion. J Cancer Res Clin Oncol, 145(2):373-381, 2019
  24. Katsumata S, Aokage K, Nakasone S, Sakai T, Okada S, Miyoshi T, Tane K,
    Hayashi R, Ishii G, Tsuboi M. Radiologic Criteria in Predicting Pathologic Less
    Invasive Lung Cancer According to TNM 8th Edition. Clin Lung Cancer,
    20(2):e163-e170, 2019
  25. Oono Y, Kuwata T, Takashima K, Shinmura K, Hori K, Yoda Y, Ikematsu H, Shitara K, Kinoshita T, Yano T. Human epidermal growth factor receptor 2-, epidermal growth factor receptor-, and mesenchymal epithelial transition factor-positive sites of gastric cancer using surgical samples. Gastric Cancer, Mar;22(2):335-343. 2019.
  26. Kawazoe A, Shitara K, Kuboki Y, Bando H, Kojima T, Yoshino T, Ohtsu A, Ochiai A, Togashi Y, Nishikawa H, Doi T, Kuwata T. Clinicopathological features of 22C3 PD-L1 expression with mismatch repair, Epstein-Barr virus status, and cancer genome alterations in metastatic gastric cancer. Gastric Cancer. 22(1):69-76. 2019.

2018年

  1. Sakai T, Aokage K, Neri S, Nakamura H, Nomura S, Tane K, Miyoshi T, Sugano M, Kojima M, Fujii S, Kuwata T, Ochiai A, Iyoda A, Tsuboi M, Ishii G. Link between tumor-promoting fibrous microenvironment and an immunosuppressive microenvironment in stage I lung adenocarcinoma. Lung Cancer. 126:64-71. 2018.
  2. Ueda T, Aokage K, Mimaki S, Tane K, Miyoshi T, Sugano M, Kojima M, Fujii S, Kuwata T, Ochiai A, Kusumoto M, Suzuki K, Tsuchihara K, Nishikawa H, Goto K, Tsuboi M, Ishii G. Characterization of the tumor immune-microenvironment of lung adenocarcinoma associated with usual interstitial pneumonia. Lung Cancer. 126:162-169. 2018.
  3. Mishima S, Kawazoe A, Matsumoto H, Kuboki Y, Bando H, Kojima T, Doi T, OhtsuA, Yoshino T, Nonte EM, Chintharlapalli S, Nasir A, Kuwata T, Shitara K. Efficacy and safety of ramucirumab-containing chemotherapy in patients with pretreated metastatic gastric neuroendocrine carcinoma. ESMO Open. 3(7):e000443. 2018.
  4. Tada Y, Togashi Y, Kotani D, Kuwata T, Sato E, Kawazoe A, Doi T, Wada H, Nishikawa H, Shitara K. Targeting VEGFR2 with Ramucirumab strongly impacts effector/ activated regulatory T cells and CD8(+) T cells in the tumor microenvironment. J Immunother Cancer. 6(1):106. 2018.
  5. Katsumata S, Aokage K, Miyoshi T, Tane K, Nakamura H, Sugano M, Kojima M, Fujii S, Kuwata T, Ochiai A, Hayashi R, Tsuboi M, Ishii G. Differences of tumor microenvironment between stage I lepidic-positive and lepidic-negative lung adenocarcinomas. J Thorac Cardiovasc Surg. 156(4):1679-1688.e2. 2018.
  6. Miura T, Mitsunaga S, Ikeda M, Ohno I, Takahashi H, Suzuki H, Irisawa A, Kuwata T, Ochiai A. Characterization of low active ghrelin ratio in patients with advanced pancreatic cancer. Support Care Cancer. 26(11):3811-3817. 2018.
  7. Nakajo K, Oono Y, Kuwata T. Case of pyloric gland adenoma accompanied by a component of foveolar epithelial-type adenoma within the lesion. Dig Endosc. 30(5):673. 2018.
  8. Naito Y, Takahashi H, Shitara K, Okamoto W, Bando H, Kuwata T, Kuboki Y, Matsumoto S, Miki I, Yamanaka T, Watanabe A, Kojima M. Feasibility study ofcancer genome alterations identified by next generation sequencing: ABC study. Jpn J Clin Oncol. 48(6):559-564. 2018.
  9. Ichikawa T, Aokage K, Sugano M, Miyoshi T, Kojima M, Fujii S, Kuwata T, Ochiai A, Suzuki K, Tsuboi M, Ishii G. The ratio of cancer cells to stroma within the invasive area is a histologic prognostic parameter of lung adenocarcinoma.  Lung Cancer. 118:30-35. 2018.
  10. Miura T, Mitsunaga S, Ikeda M, Ohno I, Takahashi H, Kuwata T, Ochiai A.  Neural Invasion Spreads Macrophage-Related Allodynia via Neural Root in Pancreatic Cancer. Anesth Analg. 126(5):1729-1738. 2018.
  11. Nakasone S, Mimaki S, Ichikawa T, Aokage K, Miyoshi T, Sugano M, Kojima M, Fujii S, Kuwata T, Ochiai A, Tsuboi M, Goto K, Tsuchihara K, Ishii G.  Podoplanin-positive cancer-associated fibroblast recruitment within cancer stroma is associated with a higher number of single nucleotide variants in cancer cells in lung adenocarcinoma. J Cancer Res Clin Oncol. 144(5):893-900. 2018.
  12. Oono Y, Kuwata T, Takashima K, Yoda Y, Ikematsu H, Shitara K, KinoshitaT, Yano T. Clinicopathological features and endoscopic findings of HER2-positive gastric cancer. Surg Endosc. 32(9):3964-3971. 2018.
  13. Ueda T, Aokage K, Nishikawa H, Neri S, Nakamura H, Sugano M, Tane K, Miyoshi T, Kojima M, Fujii S, Kuwata T, Ochiai A, Kusumoto M, Suzuki K, Tsuboi M, Ishii G. Immunosuppressive tumor microenvironment of usual interstitial pneumonia-associated squamous cell carcinoma of the lung. J Cancer Res Clin Oncol. 144(5):835-844. 2018.
  14. Nakamura H, Ichikawa T, Nakasone S, Miyoshi T, Sugano M, Kojima M, Fujii S,  Ochiai A, Kuwata T, Aokage K, Suzuki K, Tsuboi M, Ishii G. Abundant tumor promoting stromal cells in lung adenocarcinoma with hypoxic regions. Lung Cancer.  115:56-63. 2018.
  15. Nakajo K, Oono Y, Kuwata T, Yano T. A case of a protruded lesion formed by a poorly differentiated intramucosal adenocarcinoma of the stomach: an immunohistochemical analysis. Clin J Gastroenterol. 11(2):127-132. 2018.

2017年

  1. Ichikawa T, Saruwatari K, Mimaki S, Sugano M, Aokage K, Kojima M, Hishida T, Fujii S, Yoshida J, Kuwata T, Ochiai A, Suzuki K, Tsuboi M, Goto K, Tsuchihara K, Ishii G. Immunohistochemical and genetic characteristics of lung cancer mimicking organizing pneumonia. Lung Cancer. 134-139. 2017.
  2. Shitara K, Doi T, Nagano O, Fukutani M, Hasegawa H, Nomura S, Sato A, Kuwata T, Asai K, Einaga Y, Tsuchihashi K, Suina K, Maeda Y, Saya H, Ohtsu A. Phase 1 study of sulfasalazine and cisplatin for patients with CD44v-positive gastric cancer refractory to cisplatin (EPOC1407). Gastric Cancer. 20(6):1004-1009. 2017.
  3. Neri S, Miyashita T, Hashimoto H, Suda Y, Ishibashi M, Kii H, Watanabe H, Kuwata T, Tsuboi M, Goto K, Menju T, Sonobe M, Date H, Ochiai A, Ishii G. Fibroblast-led cancer cell invasion is activated by epithelial-mesenchymal transition through platelet-derived growth factor BB secretion of lung adenocarcinoma. Cancer Lett. 395:20-30. 2017.
  4. Higaki E, Yanagi S, Gotohda N, Kinoshita T, Kuwata T, Nagino M, Ochiai A, Fujii S. Intraoperative peritoneal lavage cytology offers prognostic significance for gastric cancer patients with curative resection. Cancer Sci. 108(5):978-986. 2017.
  5. Shimizu K, Kirita K, Aokage K, Kojima M, Hishida T, Kuwata T, Fujii S, Ochiai A, Funai K, Yoshida J, Tsuboi M, Ishii G. Clinicopathological significance of caveolin-1 expression by cancer-associated fibroblasts in lung adenocarcinoma. J Cancer Res Clin Oncol. 143(2):321-328. 2017.
  6. Ikemura S, Aramaki N, Fujii S, Kirita K, Umemura S, Matsumoto S, Yoh K, Niho S, Ohmatsu H, Kuwata T, Kojima M, Ochiai A, Betsuyaku T, Tsuboi M, Goto K, Ishii G. Changes in the tumor microenvironment during lymphatic metastasis of lung squamous cell carcinoma. Cancer Sci. 108(1):136-142. 2017.
  7. Goto M, Naito M, Saruwatari K, Hisakane K, Kojima M, Fujii S, Kuwata T, Ochiai A, Nomura S, Aokage K, Hishida T, Yoshida J, Yokoi K, Tsuboi M, Ishii G. The ratio of cancer cells to stroma after induction therapy in the treatment of non-small cell lung cancer. J Cancer Res Clin Oncol. 143(2):215-223. 2017.
  8. Kawazoe A, Kuwata T, Kuboki Y, Shitara K, Nagatsuma AK, Aizawa M, Yoshino T, Doi T, Ohtsu A, Ochiai A. Clinicopathological features of programmed death ligand 1 expression with tumor-infiltrating lymphocyte, mismatch repair, and Epstein-Barr virus status in a large cohort of gastric cancer patients. Gastric Cancer. 20(3):407-415. 2017.
  9. Shitara K, Doi T, Nagano O, Imamura CK, Ozeki T, Ishii Y, Tsuchihashi K,Takahashi S, Nakajima TE, Hironaka S, Fukutani M, Hasegawa H, Nomura S, Sato A, Einaga Y, Kuwata T, Saya H, Ohtsu A. Dose-escalation study for the targeting of CD44v(+) cancer stem cells by sulfasalazine in patients with advanced gastric cancer (EPOC1205). Gastric Cancer. 20(2):341-349. 2017.